A photoplethysmogram (PPG) sensor includes a pixel array that collects light, a pixel sampler that converts the light collected through the pixel array into a plurality of pixel data, an effective area determiner that determines an effective area and a non-effective area of the pixel array based on the pixel data, a power controller that is operable to cut off power to the non-effective area of the pixel array, and a PPG data generator that generates PPG data from pixel data corresponding to the effective area among the pixel data.

Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can re-programme immune cells in the spleen, modulate pro- and anti-inflammatory molecules levels, and induce disease-resolution pathways system-ically thereby reducing inflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

A method of detecting changes in blood flow in a head of a subject includes measuring a value of a parameter of a cardiac bioelectrical signal at a scalp area of the subject relative to a reference cardiac bioelectrical signal. The method also includes comparing the value of the measured parameter with a predetermined value of the parameter to determine any change in blood flow in the head of the subject. The determined change can be used to detect changes in perfusion in the brain of a subject for example, as a result of anti-coagulation medication used to dissolve a clot in a blood vessel of the brain of a subject who has experienced ischaemic stroke.

A method of detecting changes in blood flow in a head of a subject includes measuring a value of a parameter of a cardiac bioelectrical signal at a scalp area of the subject relative to a reference cardiac bioelectrical signal. The method also includes comparing the value of the measured parameter with a predetermined value of the parameter to determine any change in blood flow in the head of the subject. The determined change can be used to detect changes in perfusion in the brain of a subject for example, as a result of anti-coagulation medication used to dissolve a clot in a blood vessel of the brain of a subject who has experienced ischaemic stroke.

Provided herein are systems, methods, and media capable of determining estimated force applied on a target tissue region to enable tactile feedback during interaction with said target tissue region.

Provided herein are systems, methods, and media capable of determining estimated force applied on a target tissue region to enable tactile feedback during interaction with said target tissue region.

An optical measuring apparatus includes first and second light-emitting elements that emit light and a controller. Upon detection of the presence of a body by light emitted from the first light-emitting element, the controller performs control so that the second light-emitting element will emit light with an amount for measuring the body.

A measurement apparatus includes a light source, a sensor including light detection cells including a first light detection cell and a second light detection cell, and an electronic circuit. The circuit causes the light source to emit a light pulse, causes the first light detection cell to detect a reflected light pulse from a target in an exposure period including at least part of a period from when an intensity of the reflected light pulse starts increasing to when it starts falling and generate a first signal, causes the second light detection cell to detect the reflected light pulse in an exposure period including at least part of a trailing period from when the intensity of the reflected light pulse starts falling to when it stops falling and generate a second signal. The circuit generates, based on the first and second signals, data representing states of the target.

Provided are a leukocyte detection method, a system, an electronic device and a computer readable medium. The method comprises: acquiring a microcirculation image (S1); determining a location of an intra-tubular space of a capillary vessel from the microcirculation image (S2); and determining a leukocyte index based on image information of the intra-tubular space of the capillary vessel (S3).

Techniques are described for integrating blood pressure measurement (BPM) into a portable electronic device. For example, an input interface of the device includes an integrated force sensor. Human-discernable feedback is output to the user, while using the force sensor to monitor fingertip pressure being applied by the user on the input interface, to guide the user into a first condition in which capillary fingertip blood flow (CFBF) is occluded. The human-discernable feedback is then output to the user, while continuing to use the force sensor to monitor the fingertip pressure, to guide the user into one or more subsequent conditions that allow non-occluded CFBF signals to be sensed by one or more sensors (e.g., the force sensor, an optical fingerprint sensor, etc.). The sensed non-occluded CFBF signals can be used to generate one or more CFBF-based BPM readings for the user (e.g., which can be calibrated to arterial BPM).