Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patient is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding of the patient or implementing assessment, prediction, or estimation of a probability of bleeding of the patient following injury, in some instances, in real-time before, during, and after fluid resuscitation. According to some embodiments, one or more sensors might monitor physiological data of the patient before, during, and after resuscitation following injury. A computer system might receive and analyze the physiological data, and might estimate a probability that the patient is bleeding, based at least in part on the analyzed physiological data. An indication of at least one of an assessment, prediction, or estimate of a probability that the patient is bleeding may then be displayed on a display device.

Wireless intracranial monitors are provided. The wireless intracranial monitors comprise a main body, a wireless transceiver, a processing module, and a sensing module, in which the sensing module contains a catheter. On the catheter, a pressure sensor is configured to detect deformation of the catheter or a diaphragm connected to the pressure sensor. The detected deformation is then transmitted to the processing module through an in-catheter wire.

The device for non-invasive monitoring of intracranial pressure (1) includes a measuring mat (2), processor unit (3), device for recording electrical activity of the heart (4), device for invasive measurement of arterial blood pressure (5), imaging device 6 and network connector (7). The measuring mat includes the processor unit (3) and sensors, at least one sensor (8) monitoring mechanical movement caused by the bloodstream dynamics. The ICP calculation methods use the Windkessel model and the relation between the start of the R-wave and the time delay of the mechanical movement of the head, which is related to the reflection of the pulse wave in the head.

Methods, systems, and devices are provided for monitoring and displaying medical parameters for a patient. In one embodiment, a display can be configured to show a display screen that includes information related to a physiological parameter being measured from a patient. The information can include trends of values of the physiological parameter gathered from the patient over a period of time. The display screen can also show assessment information regarding one or more diagnostic parameters for the patient and notification information regarding one or more medically-related events that occurred as related to the patient. The trends information, the assessment information, and the notification information can be shown on the display screen alone or in any combination.

Fully-passive sensor systems that receive an input electromagnetic signal and return an output electromagnetic signal are described. The sensor systems can be used to measure pressure in biological or non-biological systems.

A novel method to noninvasively measure intracranial pressure (ICP) and more generally brain elasticity is disclosed. ICP is determined using an algorithm coupled on a simulated artificial neural network (SANN) that calculates ICP based on a determination of a set of interacted ultrasound signals (IUSs) generated from multiple ultrasound pulses. The methods and systems of the present invention are capable of rapidly determining ICP without manual review of EPG waves by a technician.

A cerebral spinal fluid shunt plug includes a shunt plug housing having a shunt valve recess formed therein and a window recess with an access hole. The cerebral spinal fluid shunt plug also includes a shunt valve shaped and dimensioned for positioning within the shunt valve recess of the shunt plug housing and a lucent disk shaped and dimensioned for the passage through the central access hole of the shunt plug housing. In another embodiment, a cerebral spinal fluid shunt plug includes a shunt plug housing having a shunt valve recess formed therein and an intracranial monitoring device recess with an access hole. A shunt valve is positioned within the shunt valve recess of the shunt plug housing and an intracranial monitoring device is passed through the central access hole of the shunt plug housing.

The disclosure provides neck collar devices and systems for the mitigation and prevention of traumatic brain injury, including concussion. Specifically disclosed are adjustable collars and systems, and collars having certain pressure sensing devices.

In one aspect, the disclosure provides a pressure sensor that wirelessly provides force/pressure data to a wireless receiver. The pressure sensor includes a first fluid-responsive membrane configured to be exposed to a region, such as a body fluid, whose pressure is being monitored. A force transducer for measuring this pressure is movable toward and away from the flexible membrane and may be oscillated, either out-of-contact with the first fluid-responsive membrane or in-contact therewith, for static/dynamic pressure sensor calibration. An actuator for displacing/oscillating the force transducer is located within the internal housing. Specific pressure transducers, fluid drainage systems, implantable devices and (at least partially) external sensing devices are disclosed. Calibration techniques, including recalibration to adjust for device drift and to clear biofouling are disclosed.

The object of providing a cerebrospinal fluid drainage system 1 which reacts precisely to changes in pressure in the cerebrospinal fluid, with ease of operation, is achieved by the present invention in that a pump 5 is used for draining the cerebrospinal fluid (liquor), wherein operating measured values supplied by sensors act as controlled variable for the operation of the pump. The pressure in the liquor line currently measured by a pressure sensor 10, the liquor pressure in the intracranial cavity being treated, measured intracorporeally by a pressure sensor, and/or the volume of liquor already pumped out, as operating measured value, can, for example, serve as the basis for operational control of the pump of the liquor drainage system. The liquor drainage system according to the invention has the advantage that the liquor is drained not only simply on the basis of the excess pressure in the intracranial cavity being treated, but is actively pumped out of the intracranial cavity in a controlled manner, in particular with constant measurement of the liquor pressure. In this way the pumping capacity can be regulated depending on requirement and the drainage pressure or the liquor pressure kept reliably within a specific pressure range.