Patent classifications
A61B5/0515
Apparatus and method for nano magnetic particle imaging
Disclosed herein is a nano-magnetic-particle-imaging apparatus, including a measurement head including excitation and detection coils and accommodating a sample bed for a sample including nano magnetic particles; a gradient magnetic field generation unit for generating a magnetic field having a strength equal to or greater than that of the saturation magnetic field of the nano magnetic particles in a spacing area between identical magnetic poles facing each other and forming a field-free region in a portion thereof; a first driving unit for linearly moving the sample bed; a second driving unit for rotating the gradient magnetic field generation unit in a plane; a third driving unit for linearly reciprocating the gradient magnetic field generation unit; and a control unit for applying a signal to the excitation coil, controlling the driving units, and imaging 3D distribution of the nano magnetic particles based on a detection signal output from the detection coil.
Apparatus and method for nano magnetic particle imaging
Disclosed herein is a nano-magnetic-particle-imaging apparatus, including a measurement head including excitation and detection coils and accommodating a sample bed for a sample including nano magnetic particles; a gradient magnetic field generation unit for generating a magnetic field having a strength equal to or greater than that of the saturation magnetic field of the nano magnetic particles in a spacing area between identical magnetic poles facing each other and forming a field-free region in a portion thereof; a first driving unit for linearly moving the sample bed; a second driving unit for rotating the gradient magnetic field generation unit in a plane; a third driving unit for linearly reciprocating the gradient magnetic field generation unit; and a control unit for applying a signal to the excitation coil, controlling the driving units, and imaging 3D distribution of the nano magnetic particles based on a detection signal output from the detection coil.
DETERMINING SUBTYPES OF SCHIZOPHRENIA IN A SUBJECT, TREATMENT OF SCHIZOPHRENIA, MEDICAMENT FOR TREATING SCHIZOPHRENIA AND DETERMINING THE EFFICACY OF SUCH MEDICATION
Methods of categorisation of schizophrenia sufferers into subtypes based on changes in brain morphology, together with associated blood biomarkers are provided. The methods allow for more accurate treatment and diagnosis of schizophrenia.
DETERMINING SUBTYPES OF SCHIZOPHRENIA IN A SUBJECT, TREATMENT OF SCHIZOPHRENIA, MEDICAMENT FOR TREATING SCHIZOPHRENIA AND DETERMINING THE EFFICACY OF SUCH MEDICATION
Methods of categorisation of schizophrenia sufferers into subtypes based on changes in brain morphology, together with associated blood biomarkers are provided. The methods allow for more accurate treatment and diagnosis of schizophrenia.
Physiological measurement using wearable device
A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.
Physiological measurement using wearable device
A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.
Systems and methods for magnetic material imaging
Magnetic material imaging (MMI) system including first and second sets of field-generating coils. Each of the field-generating coils of the first and second sets has an elongated segment that extends along an imaging axis of the medical imaging system. The imaging axis extends through a region-of-interest (ROI) of an object. The elongated segments of the first set of field-generating coils are positioned opposite the elongated segments of the second set of field-generating coils and the ROI is located between the first and second sets of field-generating coils. The MMI system also includes a coil-control module configured to control a flow of current through the first and second sets of field-generating coils to generate a selection field and to generate a drive field. The selection and drive fields combine to form a movable 1D field free region (FFR) that extends through the ROI.
CABLING ARRANGMENT, COIL APPARATUS AND APPARATUS FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES
The present invention relates to a cabling arrangement and a coil apparatus for use in an MPI apparatus to increase the sensitivity of the apparatus. The cabling arrangement comprises a first AC terminal (320), a second AC terminal (330), wherein said first and second AC terminals are configured for coupling an AC voltage between them, a first internal terminal (301), a second internal terminal (302), wherein said first and second internal terminals are configured for coupling a DC voltage between them, a first subset of one or more first conductors (401) coupled between the first internal terminal and the second AC terminal, and a second subset of one or more second conductors (402) coupled between the second internal terminal and the second AC terminal, wherein said first and second conductors are arranged to form a coil (125, 126, 127; 601, 602, 603, 604) to generate a magnetic field in a zone of interest.
Precision Delivery of Angularly Separate Beams of Energy Utilizing Holographic Energy Teleportation (HET) with Time-Correlated Standing-Wave Interference and Coherent Intensity Amplification
By producing the proper wave interference using superimposed angularly separate waves that overlap with the proper time-phase relationship (called “Time-Correlated Standing-wave Interference”), wave energy is amplified (by “Coherent Intensity Amplification”) and teleported to precise locations. For instance, in one application, energy is teleported to one or more areas within a living body for such therapeutic applications as destroying cancer cells or plaques within arteries. A system implementing this technique creates amplified constructive interference at one or more selected disease locations, while producing destructive interference at surrounding locations. In this application example, the technique allows energy to be “teleported” to tumor cells, plaques, or other diseased cells, for instance, to destroy them, while surrounding healthy cells receive virtually no energy, obviating collateral damage from the treatment. The same method can be used to diagnose disease by detecting energy teleported to different locations.
MAGNETIC PARTICLE IMAGING DEVICE
A static magnetic field generator generates a non-magnetic field region. An AC magnetic field application instrument applies an AC magnetic field to the non-magnetic field region. A detection coil has an axis parallel to a direction of the AC magnetic field in order to detect a magnetization signal. A measuring instrument is connected to the detection coil. A resonance frequency variable device includes a capacitor connected in parallel to the detection coil in order to adjust a resonance frequency of the detection coil and the measuring instrument. A capacity of the capacitor is adjusted such that a resonance frequency of a closed circuit including the detection coil, the measuring instrument, and the resonance frequency variable device including the capacitor coincides with a frequency of a harmonic signal.