A novel medical device that utilizes, for diagnosis and other medical uses, the detection of emitted radiofrequency (RF) signals experimentally shown as spontaneously emitted by a non-equilibrium population of spin polarized electrons in chiral media during their relaxation to equilibrium. The emitted RF signals correspond to the Zeeman spin-flip energy of electrons under the influence of a magnetic field (MF), which in the absence of an external MF are too difficult to detect. Using a larger MF shifts the low energy, low frequency RF emission of spin polarized electrons to a higher RF power emission wave characterized by a fixed resonant frequency. The detection of these higher RF power emissions is relatively easy using conventional MF magnet sources and antenna receiver technology.

A phase compensation circuit includes a phase difference voltage detection module configured to process an inputted detection signal and an inputted reference signal, calculate a magnitude ratio or a phase difference of the processed detection signal and reference signal, and then output a first phase difference voltage signal according to the amplitude ratio or the phase difference. A compensation voltage adjustment module is configured to collect an ambient temperature parameter, determine a first compensation voltage corresponding to the ambient temperature parameter according to a corresponding relationship between a preset temperature parameter and a compensation voltage, perform voltage division on a voltage value inputted from a voltage input terminal according to the first compensation voltage, and output a compensation voltage signal; and a A compensation module is configured to compensate for the first phase difference voltage signal according to the compensation voltage signal and output a second phase difference voltage signal.

A phase compensation circuit includes a phase difference voltage detection module configured to process an inputted detection signal and an inputted reference signal, calculate a magnitude ratio or a phase difference of the processed detection signal and reference signal, and then output a first phase difference voltage signal according to the amplitude ratio or the phase difference. A compensation voltage adjustment module is configured to collect an ambient temperature parameter, determine a first compensation voltage corresponding to the ambient temperature parameter according to a corresponding relationship between a preset temperature parameter and a compensation voltage, perform voltage division on a voltage value inputted from a voltage input terminal according to the first compensation voltage, and output a compensation voltage signal; and a A compensation module is configured to compensate for the first phase difference voltage signal according to the compensation voltage signal and output a second phase difference voltage signal.

Systems and methods for performing and assessing neuromodulation therapy are disclosed herein. One method for assessing the efficacy of neuromodulation therapy includes positioning a neuromodulation catheter at a target site within a renal blood vessel of a human patient and delivering neuromodulation energy at the target site with the neuromodulation catheter. The method can further include obtaining a measurement related to a dimension of the renal blood vessel via a sensing element of the neuromodulation catheter. The measurement can be compared to a baseline measurement related to the dimension of the renal blood vessel to assess the efficacy of the neuromodulation therapy. In some embodiments, the baseline measurement is obtained via the sensing element of the neuromodulation catheter prior to delivering the neuromodulation energy.

Embodiments of tissue monitoring and therapy systems and methods are disclosed. In some embodiments, a monitoring and therapy system comprises collecting video images of a tissue site, amplifying said video images via Eulerian Video Magnification, and determining a treatment parameter from the amplified video images detectable by Eulerian Video Magnification. If the treatment parameter differs from a threshold, an alert may be generated.

Embodiments of tissue monitoring and therapy systems and methods are disclosed. In some embodiments, a monitoring and therapy system comprises collecting video images of a tissue site, amplifying said video images via Eulerian Video Magnification, and determining a treatment parameter from the amplified video images detectable by Eulerian Video Magnification. If the treatment parameter differs from a threshold, an alert may be generated.

There is provided a phase-domain detection apparatus for MIT application. The phase-domain detection apparatus includes a phase-locked loop unit configured to generate a plurality of reference clock signals having different phases and a phase-domain detection unit. The phase-domain detection unit is configured to receive the reference clock signals from the phase-locked loop unit, receive a response clock signal that is a phase-shifted reference clock signal of a reference clock signal inputted and passed through to a target object among the reference clock signals, and detect a phase difference between the reference clock signal inputted to the target object and the response clock signal.

A physiological parameter inductive sensing system has a loop resonator which inductively couples with electromagnetic signals emitted from the body. The loop resonator forms part of an oscillator circuit, and negative feedback control is used to control the oscillator circuit, based on a measured oscillation amplitude. Within the feedback control loop, an analog to digital converter is used with a first number of bits (or trits), and successive outputs of the analog to digital converter are combined to derive an output value with a resolution of a second number of bits, greater than the first number of bits (or trits). The feedback control of the amplitude of the oscillator circuit is achieved using the output value.

A physiological parameter inductive sensing system has a loop resonator which inductively couples with electromagnetic signals emitted from the body. The loop resonator forms part of an oscillator circuit, and negative feedback control is used to control the oscillator circuit, based on a measured oscillation amplitude. Within the feedback control loop, an analog to digital converter is used with a first number of bits (or trits), and successive outputs of the analog to digital converter are combined to derive an output value with a resolution of a second number of bits, greater than the first number of bits (or trits). The feedback control of the amplitude of the oscillator circuit is achieved using the output value.

A magnetically shielded room, that is capable of suppressing positional deviation of a measuring tool in an internal space, has an upper shielding body, a side periphery shielding body, and a lower shielding body, which form a magnetically shielded internal space of the magnetically shielded room. A pedestal has a higher rigidity than the lower shielding body, and is located on an under surface of the lower shielding body. First and second supporting members are located on and stand erect from the pedestal. The first and second supporting members penetrate the lower shielding body and extend into the internal space.