Devices, systems, and methods for visualizing a reference location of an electrophysiology device in an anatomical image are provided. According to one embodiment, an electrophysiological mapping and guidance system includes a processor circuit in communication with a catheter carrying a plurality of electrodes. The processor circuit controls the plurality of electrodes to obtain electrical measurements (e.g., voltage measurements) of an electrical field induced within an anatomical cavity. The processor circuit computes a reference location of the plurality of electrodes based on distortions in the electromagnetic field detected at a first time, computes a current location of the plurality of electrodes based on distortions in the electromagnetic field detected at a later second time, and outputs a signal to cause simultaneous display of a first visualization of the reference location and a second visualization of the current location.

A device may be configured with a housing having a reservoir and an outlet separated by a heat rupturable membrane. The membrane may serve to separate a material held within the reservoir from the outlet until the membrane is ruptured. The membrane may include a heater configured to selectively rupture the membrane when actuated. The heater may be physically removed and/or thermally insulated from at least one of an environment surrounding the device and the reservoir.

An intravenous therapy system may include a hollow needle comprising a distal end and a proximal end, the distal end comprising a sharp tip for insertion into a vein; an infrared (IR) camera placed within a hollow portion of the hollow needle, including: an IR detector; a first light source to emit a first wavelength of IR light; and a second light source to emit a second wavelength of IR light; a comparator to, upon execution of a processor communicatively coupled to the comparator, compare an amount of reflected light received at the IR detector during activation of the first light and second light and provide an indication of light absorption within a vein.

A cytology sampling system includes a catheter tube and a cytology tool. The catheter tube has open proximal and distal ends. The cytology tool is insertable through the catheter tube and includes a flexible shaft, a brush, and a position sensor. The flexible shaft defines proximal and distal ends thereof. The brush is coupled to the distal end of the flexible shaft. The brush includes a plurality of brush shafts. Each brush shaft has bristles disposed along a portion of a length thereof. The bristles are coupled to and extend radially away from an outer surface of each of the brush shafts. The bristles are configured to collect cell samples from targeted tissue of a patient. The position sensor provides an indication of the location of the position sensor within a luminal structure. The system may include a positioning assembly for placing the distal end of the catheter tube adjacent the target tissue.

According to one embodiment, a tissue penetrating device includes an elongate shaft having a proximal end, a distal end, and a lumen extending there between. A first needle is disposed within the lumen of the elongate shaft and is extendable therefrom between a first configuration and a second configuration. In the first configuration, the first needle is disposed within the elongate shaft's lumen and is substantially aligned with an axis of the lumen. In the second configuration, the first needle extends distally of the elongate shaft's distal end and bends away from the lumen's axis. A second needle is disposed within a lumen of the first needle and is extendable therefrom when the first needle is positioned in the first configuration and when the first needle is positioned in the second configuration. The second needle may be extended from the first needle to penetrate tissue of a patient.

Systems and methods for planning and performing image free implant revision surgery are discussed. For example, a method for generating a revision plan can include collecting pre-defined parameters characterizing a target bone, generating a 3D model, collecting a plurality of surface points, and generating a reshaped 3D model. Generating the 3D model of the target bone can be based on a first portion of the pre-defined parameters. Generating the reshaped 3D model can be done based on the plurality of surface points collected from a portion of the surface of the target bone.

Techniques for segmenting a percutaneous medical procedure based on one or more determinable phases. The techniques may include obtaining a first set of features over a first time period. The first set of features may be derived from instrument telemetry data corresponding to an endoluminal scope instrument. The technique may also include obtaining a second set of features over the first time period. The second set of features may be derived from instrument telemetry data corresponding to a percutaneous needle instrument. Based on the first set of features and the second set of features, the techniques may classify at least a portion of the first time period as a first phase of the percutaneous medical procedure.

Methods and systems for autonomous cardiac mapping are disclosed. An example system for autonomous cardiac mapping of a heart chamber includes a processor being configured to acquire a representative geometric shell of the heart chamber, control a robotic device to autonomously navigate a mapping probe to a plurality of locations within the heart chamber based at least in part on the representative geometric shell, and generate a three-dimensional electroanatomical map of the heart chamber based on electrical data collected by the probe at the plurality of locations.

Disclosed catheter insertion systems enable the user to identify the location of the needle based on the electrical properties of subcutaneous tissue relative the electrical properties of other fluids such as blood or air. Disclosed systems can include one or more of the following features: 1) the catheter assembly is modular (e.g., the catheter can be connected and disconnected from the detection unit at will); 2) the detection unit employs an electrical circuit that allows for the discernment between subcutaneous tissue and blood; 3) the system assists the end user with catheter advancement. Some embodiments can be used to insert catheters into a spaces where the needle passes first through subcutaneous fat and muscle before entering fluid or air.

A magnetometer-based metal detection device and methods of use are described. The device includes a proximal portion, a central body and a distal portion, and at least one magnetometer positioned within or on the distal portion. The at least one magnetometer includes at least one sensor capable of sensing a magnetic field in three orthogonal axes. Also described is a method of calibrating the device to achieve rotational invariance, and a method of determining a directionality or directional line along which a target metal object lies.