An adherent device to monitor a patient for an extended period comprises a breathable tape. The breathable tape comprises a porous material with an adhesive coating to adhere the breathable tape to a skin of the patient. At least one electrode is affixed to the breathable tape and capable of electrically coupling to a skin of the patient. A printed circuit board is connected to the breathable tape to support the printed circuit board with the breathable tape when the tape is adhered to the patient. Electronic components electrically are connected to the printed circuit board and coupled to the at least one electrode to measure physiologic signals of the patient. A breathable cover and/or an electronics housing is disposed over the circuit board and electronic components and connected to at least one of the electronics components, the printed circuit board or the breathable tape.

Disclosed is a bioimpedance measurement system: A stabilized high frequency current generator is connected to PadSet electrodes via a Patient Cable. Electrodes are connected to an adaptive circuit that conditions the resulting voltage signal and converts it to digital form. Firmware performs signal acquisition and relays data to the device.

Disordered breathing events may be classified as central, obstructive or a combination of central an obstructive in origin based on patient motion associated with respiratory effort. Central disordered breathing is associated with disrupted respiration with reduced respiratory effort. Obstructive disordered breathing is associated with disrupted respiration accompanied by respiratory effort. A disordered breathing classification system includes a disordered breathing detector and a respiratory effort motion sensor. Components of the disordered breathing classification system may be fully or partially implantable.

An apparatus may include a sensing circuit and a processor. The sensing circuit is configured to generate a sensed physiological signal, wherein the physiological signal includes respiration information of a subject. The processor includes an end expiratory volume (EEV) module configured to determine a value of EEV of the subject using the sensed physiological signal, and a lung hyperinflation detection module configured to generate an indication of lung hyperinflation of the subject according to the value of EEV and provide the indication to at least one of a user or process.

A system may include a port, at least one sensing circuit, and at least one processor. The port is configured to receive an indication of dosing of medication to treat a pulmonary condition of a heart failure (HF) subject and the at least one sensing circuit configured to sense at least one physiological signal, wherein the physiological signal includes physiological information of the HF subject. The at least one processor includes a parameter module configured to extract values of at least one physiological parameter indicative of health status of the HF subject, and a trending module configured to trend extracted values of the at least one physiological parameter and detect an effect of the dosing of the medication on the HF subject using the trending of the extracted values of the at least one physiological parameter.

A bio impedance measurement apparatus includes a current applicator configured to provide, to terminals contacting a body, a current based on a first control signal, and a modulator configured to modulate a voltage generated as the current flows through the body, based on a second control signal. The apparatus further includes an amplifier configured to amplify the modulated voltage, and a demodulator configured to demodulate the amplified voltage based on a third control signal.

An apparatus of processing a signal or a biosignal, and a method of processing a signal or a biosignal are provided. The method of processing signal involves receiving a first reference signal having a frequency component of a measurement signal to be applied to a subject, receiving a second reference signal having a frequency component within a frequency bandwidth of an amplifier, and converting a first signal measured from the subject to a second signal within the frequency bandwidth of the amplifier, based on the first reference signal and the second reference signal.

Embodiments of the disclosure include systems and methods for reducing false positives in detection of pauses. For example, embodiments include a sensing component configured to obtain values of a first physiological parameter and determine a cardiac pause based on the values of the first physiological parameter. Furthermore, embodiments include performing a validation check of the determined cardiac pause using at least one of: the values of the first physiological parameter or values of a second physiological parameter.

A wearable sensor and method for providing a wearable sensor are disclosed. In a first aspect, the wearable sensor comprises a first module, wherein the first module comprises a top layer, a printed circuit board (PCB) layer, and a bottom layer. The bottom layer comprises a double adhesive layer that adheres to both the PCB layer and the user. The bottom layer includes at least two openings to house at least two electrodes for monitoring of a user. The wearable sensor further comprises a second module coupled to the first module, wherein the first module is disposable and the second module is reusable. In a second aspect, the method comprises providing the aforementioned wearable sensor.

A medical device for measuring an impedance of a patient or mammal when a current is applied by electrodes. The medical device includes an output transmits a drive signal to a set of drive electrodes coupled to a patient and an input receives a sense signal generated by a set of sensing electrodes coupled to the patient. A processor determines the impedance of the patient based on the drive signal transmitted to the set of drive electrodes and the sense signal received by the set of sensing electrodes.