A process and a device determine an indicator of an intrinsic end-expiratory pressure in the lungs of a patient. Embodiments are based on the device, ventilator with the device, and the process using the device that includes an interface arrangement configured for an exchange of information with a ventilation device and a control unit that determines first information on a first breathing pressure generated by muscles of the patient, at a first time, at which an inhalation attempt of the patient is present and determines second information on a second breathing pressure generated by the muscles of the patient, at a second time, at which breathing gas flow towards the patient starts. The control unit further determines the indicator of the intrinsic end-expiratory pressure based on the first information and based on the second information.

A system for assessing extubation includes a respiratory assistance device, an artificial intelligence platform, and a hospital information system. The respiratory assistance device is adapted to communicate with a trachea of a patient. The artificial intelligence platform includes a prediction module. A method for assessing extubation includes the following steps. Measured values of respiratory parameters of the patient are recorded by the respiratory assistance device. The recorded times and the measured values of the respiratory parameters corresponding to each of the recording times are transmitted to the artificial intelligence platform. The prediction module analyzes the measured values of respiratory parameters within a predetermined time period according to a prediction model to generate a prediction result. The prediction result is transmitted to the hospital information system and is recorded into a medical record of the patient. With such design, a reference for extubation assessment that is more accurate is provided.

The present invention provides a method and apparatus for treating a subject suffering from obstructive sleep apnea (OSA). In one embodiment, the method of the present invention is configured to deliver negative airway pressure to a subject's airway to strengthen the airway muscle tone.

A method of treating a human subject which is effected by inhalation of gaseous nitric oxide, the method comprising a first treatment period comprising administering gNO by inhalation over a period of about at least 5 days, wherein the first treatment period is followed by a second treatment period comprising administering gNO by inhalation over a period of at least 3 months. The method can be utilized for treating a human subject suffering from, or prone to suffer from, a disease or disorder that is manifested in the respiratory tract, or from a disease or disorder that can be treated via the respiratory tract.

This disclosure concerns an exhaled breath collection device (1000) comprising a sensor unit (100) configured to measure a biomarker in exhaled breath, a cooling device configured to reduce a temperature of exhaled breath, a mouthpiece (300) configured to direct exhaled breath towards the cooling device, and a temperature control unit. In the exhaled breath collection device of the present disclosure, the temperature control unit is configured to control the cooling device to reach a target temperature which is set appropriately to correspond with the biomarker to be analysed.

This disclosure concerns an exhaled breath collection device (1000) comprising a sensor unit (100) configured to measure a biomarker in exhaled breath, a cooling device configured to reduce a temperature of exhaled breath, a mouthpiece (300) configured to direct exhaled breath towards the cooling device, and a temperature control unit. In the exhaled breath collection device of the present disclosure, the temperature control unit is configured to control the cooling device to reach a target temperature which is set appropriately to correspond with the biomarker to be analysed.

An electronic vaporizer system includes an anesthetic sump containing anesthetic agent, a vaporizer unit that vaporizes the anesthetic agent from the sump and delivers the vaporized agent to a patient breathing circuit, and a gas sensor configured to measure end tidal concentration of the anesthetic agent and exhalation gasses from the patient. A control system is configured to receive the measured end tidal concentration of anesthetic agent and compare the measured end tidal concentration to a desired end tidal concentration to be maintained for the patient. The vaporizer unit is then automatically controlled to deliver an amount of vaporized agent to the patient based on the comparison.

A device for measuring a concentration of a component in a target sample includes a flow chamber with a first channel that receives a reference sample having a known concentration of the component. The flow chamber also includes a second channel that receives the target sample having an unknown concentration of the component. A pump operates to pump the reference sample and the target sample at a same volume flow rate through the first and second channels, respectively. A thermal mass flow meter measures a thermal conductivity of the reference sample, a thermal conductivity of the target sample, or both.

A device for measuring a concentration of a component in a target sample includes a flow chamber with a first channel that receives a reference sample having a known concentration of the component. The flow chamber also includes a second channel that receives the target sample having an unknown concentration of the component. A pump operates to pump the reference sample and the target sample at a same volume flow rate through the first and second channels, respectively. A thermal mass flow meter measures a thermal conductivity of the reference sample, a thermal conductivity of the target sample, or both.

A detection device for detecting characteristics of a mixed fluid containing different types of substances with different thermal properties within a prescribed range, includes: one or a plurality of heaters for heating the mixed fluid; a plurality of temperature detectors for detecting the temperature of the mixed fluid heated; a flow rate calculation unit for calculating the flow rate of the mixed fluid using the output from at least a portion of the plurality of temperature detectors; a correspondence relation storage unit that stores the correspondence relation between the output from the temperature detectors for a prescribed flow rate and the mixture ratio of the substances in the mixed fluid; and a mixture ratio calculation unit for calculating the mixture ratio of the substances in the mixed fluid on the basis of the output from the temperature detectors and the correspondence relation.