Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.

Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member.

A functional device is disclosed that can collect and process data/information/parameter values from one or more sensors and compares the same with one or more predefined/threshold value to suggest one or more actions and/or generate alerts/messages/suggestions to be performed by one or a combination of remote system, wearer, home automation network, healthcare provider, doctor, caretaker, among other stakeholders. Communication between the functional device, home automation server and a computational server that stores the data is also disclosed.

The invention provides a method of determining turbidity and concentration simultaneously a sample by irradiating the sample with a single incident wavelength and simultaneously measuring wavelength shifted (IE) and unshifted (EE) light emitted. A relative volume of light emitted from two phases may be determined, wherein the two phases comprise a first Rayleigh and Mie scattering and fluorescent phase associated with suspended particles, and a second, non-scattering but fluorescent phase associated with suspending solution. Volumes of the phases and/or concentrations of specific fluorophores or Raman active species are calculated from the volume of light emitted by the first phase relative to the total volume of light emitted from the first and second phases.

A technology for a wearable medical device for monitoring medical parameters. Medical measurement data can be received at the wearable medical device from a medical measurement sensor attached to the wearable medical device or a medical measurement sensor in communication with the wearable medical device. A calibration coefficient can be determined for calibrating the wearable medical device based on the medical measurement data. The wearable medical device can be calibrated based on the calibration coefficient.

an object information acquiring apparatus comprises a light emission unit configured to emit light beams from a plurality of emission positions; a conversion unit configured to convert acoustic waves generated when an object is irradiated with the light beams emitted by the light emission unit into electric signals; a beam profile acquisition unit configured to acquire information relating to beam profiles of the light beams emitted by the light emission unit, the beam profiles corresponding respectively to the plurality of emission positions; and a characteristic information acquisition unit configured to acquire characteristic information of the object on the basis of the information relating to the beam profiles corresponding to the plurality of emission positions and the electric signals.

A mobile device, methods and systems provide the invention mobile Personal Health Records (PHR) management platform solution. The platform enables secure PHR data management, measuring user's medical parameters, managing PHR secured depository containing user's health data on the user's invention combined phone & add-on sleeve device, while blocking none legitimate users access to the invention devices secured storage content. The invention device user's authentication is based on the combined weighted fusion of at least two different human biological sensors within the device and their weighted output analysis. The multi-sensors ensure bio-authentication secured memory entry only for the legitimate device user. In case of authentication success it activates various types of applications on the user PHR data depository content stored in device. The system supports the user's PHR remote health management, remotely monitoring the user's measured medical parameters, updating & managing user's health medical history depository in the user's electronic sleeve.