Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Systems, devices and methods are provided for the integration of an analyte data reader and a medication delivery device. The integrated device can include a medication delivery portion, wireless communications circuitry configured to receive data indicative of an analyte level, and electronics. The integrated device can also include one or more near-field communication (NFC) antennas. Example embodiments of adverse condition protection features of the integrated device are also provided.

A system includes a controller that is in communication with a medication delivery device and that includes control logic. The control logic is operative to: calculate a meal bolus; calculate a meal bolus correction that is based, at least in part, on a glucose level and also whether the glucose level is above or below a threshold; and calculate a corrected meal bolus based, at least in part, on the meal bolus and the meal bolus correction.

Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.

A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.

An electronic device, a method to be executed by an electronic device, and a non-transitory memory storing a program for causing an electronic device to execute processes include acquiring a pulse wave of a subject, and estimating a blood glucose level and/or a lipid level of the subject based on a displacement ratio in the pulse wave. The displacement ratio comprises a ratio between a displacement of the pulse wave at a peak of the pulse wave and a displacement of the pulse wave at a predetermined time after the peak of the pulse wave, and the predetermined time is a fixed value.

A method of preparing a working electrode on a sensor substrate is disclosed. A sensor substrate is provided and has a first side with at least one conductive trace. A layer of sensing material is applied onto the first side and covers at least a portion of the at least one conductive trace. The sensing material is irradiated with a laser beam to partially remove the layer of the sensing material while preserving a portion of the sensing material covering the at least one conductive trace, resulting in a working electrode on the sensor substrate. A membrane layer is applied that at least partially covers the working electrode. The membrane layer includes a cross-linker that cross-links at least a part of the sensing material. A diffusion step is performed during which the cross-linker in the membrane layer at least partially diffuses into the sensing material.

Provided is a blood measurement device capable of accurately estimating the amount of a component contained in blood by passing light beams for calculating the amount of the component contained in blood along the same optical axis. A blood measurement device 10 of the present invention includes a light emitting part 11 having a first light emitting part 111 and a second light emitting part 112, a light receiving part 19, an actuator 16, and a computation and control part 17 that estimates a glucose level and controls operation of the actuator 16. When applicating a first light beam from the first light emitting part 111 to a measurement site, the computation and control part 17 causes the actuator 16 to move a light emission point of the first light emitting part 111 onto an optical axis 22 defined to penetrate through the measurement site, and when applicating a second light beam from the second light emitting part 112 to the measurement site, the computation and control part 17 causes the actuator 16 to move a light emission point of the second light emitting part 112 onto the optical axis 22.