A method for forming an enzymatic biosensor includes preparing an aqueous solution including an enzyme and photocurable components, depositing the aqueous solution on a surface of a working electrode of a substrate, illuminating the working electrode with ultraviolet (UV) light to cure the aqueous solution, and crosslinking the enzyme deposited on the working electrode with solution phase or vapor phase crosslinking after curing the aqueous solution.

A device for determining the amount or concentration of an analyte in a fluid sample and a flow rate of the fluid sample in a channel is provided. The device includes a chamber including a channel and an opening the channel in fluid communication with the opening. The device further includes a wicking component positioned adjacent to the opening configured to receive an amount of fluid from the channel. The device may further include an analyte sensor positioned on the wicking component, the analyte sensor configured to detect an analyte in fluid in contact with the analyte sensor, wherein the wicking component is configured to contact the amount of fluid with the analyte sensor. Alternatively the device may include at least one pair of electrodes configured to determine a flow rate of the fluid in the channel.

An electrochemical sensor including a working electrode having an arrangement of pillars defining channels between the pillars. The channels increase confinement of a byproduct produced in an electrochemical reaction used during sensing of an analyte, so as to increase interaction of the byproduct with the working electrode. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

An electrochemical sensor including a working electrode having an arrangement of pillars defining channels between the pillars. The channels increase confinement of a byproduct produced in an electrochemical reaction used during sensing of an analyte, so as to increase interaction of the byproduct with the working electrode. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

An analyte sensor and methods and systems related thereto, where at least one or more of a lower portion of a sensor tail substrate, at least one electrode, a sensing element, a membrane, and an optional non-electrochemical functional layer comprise an antimicrobial quality. Asymmetric, double-sided adhesive binders suitable for adhering the analyte sensor to a skin surface comprising a non-woven scrim, a first pressure-sensitive adhesive layer, a second pressure-sensitive adhesive layer. Overbandages comprising a vapor-permeable backing, an aperture to circumferentially surround a sensor housing, a contact adhesive layer, first and second peelable release liners, and a third peelable release liner disposed upon an anchoring adhesive strip of the contact adhesive layer.

An analyte sensor and methods and systems related thereto, where at least one or more of a lower portion of a sensor tail substrate, at least one electrode, a sensing element, a membrane, and an optional non-electrochemical functional layer comprise an antimicrobial quality. Asymmetric, double-sided adhesive binders suitable for adhering the analyte sensor to a skin surface comprising a non-woven scrim, a first pressure-sensitive adhesive layer, a second pressure-sensitive adhesive layer. Overbandages comprising a vapor-permeable backing, an aperture to circumferentially surround a sensor housing, a contact adhesive layer, first and second peelable release liners, and a third peelable release liner disposed upon an anchoring adhesive strip of the contact adhesive layer.

Methods and analyte sensors including at least a first working electrode having a first active area thereon, and performing a dip coating operation to deposit a bilayer membrane upon the first working electrode and the first active area. The bilayer may include an inner layer having a first membrane polymer and an outer layer having a second membrane polymer, the first membrane polymer and the second membrane polymer differing from one another. The dip coating operation may comprise one or more first dips in a first membrane formulation to form the inner layer of the bilayer membrane and one or more second dips in a second membrane formulation to form the outer layer of the bilayer membrane upon the inner layer.

A stretch-deforming electrode includes a stretching portion. The stretching portion has a first stretching range and a second stretching range, in which the stretching portion has a first length variation and a first resistance variation in the first stretching range and a second length variation and a second resistance variation in the second stretching range. The first resistance variation remains substantially unchanged when the first length variation changes, the second resistance variation changes when the second length variation changes. The second resistance variation is represented by R2, the second length variation is represented by L2, and R2=A×L2, in which A is a positive number between 0.05 and 2.

A medical device capable of transmitting a radiofrequency signal to and/or receiving a radiofrequency signal from an external device is provided. The medical device comprises at least one component that contains a polymer composition that exhibits a dielectric constant of greater than about 6 at a frequency of 2 GHz, wherein the polymer composition includes a liquid crystalline polymer.

A medical device capable of transmitting a radiofrequency signal to and/or receiving a radiofrequency signal from an external device is provided. The medical device comprises at least one component that contains a polymer composition that exhibits a dielectric constant of greater than about 6 at a frequency of 2 GHz, wherein the polymer composition includes a liquid crystalline polymer.