Patent classifications
C08G73/0253
POLYMER AND TRIAZINE COMPOUND
A polymer having a high refractive index and providing a molded product that has excellent solvent resistance; a triazine compound; a method for producing the triazine compound; a method for producing the polymer using the triazine compound; a non-photosensitive liquid composition including the polymer; a method for producing a molded product using the composition; a molded product of the composition; a film formed from the molded product; a microlens formed from the molded product; and an optical element including the microlens. A polymer including a unit having a specific structure in which an aromatic group having a hydroxy group protected with a tert-butoxycarbonyloxy group, a tert-butoxycarbonylamino group, or an acetal protecting group is linked to a triazine ring through a specific linking group.
Nanoparticles functionalized with sulfur-containing polymers
A functionalized nanomaterial, such as a nanoparticle, can include a polythioaminal functionalized surface. The polythioaminal linked to the surface of the nanomaterial can be bonded to a compound such as therapeutic and/or diagnostic materials. The thiol-based linkages can be used to bond the polythioaminal to both the nanomaterial and the therapeutic and/or diagnostic materials. Polythioaminals can be prepared via reactions of triazine and dithiols. Polythioaminals thus prepared can be further modified to provide linkages to the nanomaterial and other compounds such as medicinal compound, peptides, and dyes. Nanomaterials including such compounds linked thereto via the polythioaminal can be supplied for therapeutic and/or diagnostic purposes to biological target regions.
Sulfone-resin containing gas-barrier adhesive
The invention relates to a composition comprising a sulfone-group containing resin obtainable by reaction of a polyamine containing at least one sulfone-group with a polyepoxide and optionally a hardener, as well as adhesives and coating compositions comprising said compositions having gas-barrier properties, methods for bonding substrates using said adhesives and the thus obtained articles as well as the use of the compositions described herein as adhesive or coatings having gas-barrier properties.
Amphoteric polymers and use in inkjet ink compositions
Disclosed herein are inkjet ink compositions comprising a polymer comprising the repeat units (A), (B), and (C), wherein: (A) is selected from N.sup.+(R.sub.1)(R.sub.2) and N(R.sub.1); (B) is selected from C.sub.1-C.sub.10 alkylene; C.sub.3-C.sub.20 cycloalkylene; C.sub.3-C.sub.20 heterocycloalkylene; arylene; heteroarylene; C.sub.2-C.sub.20 ether; C.sub.2-C.sub.20 thioether; C.sub.2-C.sub.20 ester; C.sub.2-C.sub.20 acetal; C.sub.2-C.sub.20 amide; bisphenols; and oligomer and polymer moieties selected from polyether, polyester, polyamines, polycarbonate, polyacetal, polythioether, polyester amide, polyurethane, polyacrylate, polyolefin, and polyalkylsiloxane, and (C) comprises at least one group selected from: (i) C(R.sub.3) (R.sub.4)C(R.sub.5)(OH)(C(R.sub.6)(R.sub.7))m-, (ii) C(R.sub.3)(R.sub.4)C(R.sub.5)(H)C(O), and (iii) C(R.sub.3)(R.sub.4)C(R.sub.5)(H)S(O)(O); and (A) is bonded to the C(R.sub.3)(R.sub.4) group of (C), and (B) is bonded to (C).
POLYMERIZABLE COMPOSITION
The polymerizable composition of the present application may exhibit a wide process window to have excellent workability, and may form a phthalonitrile resin having excellent heat resistance or a prepolymer thereof.
Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery
Degradable polymers were synthesized that self-assemble with nucleic acids, proteins, hydrophobic drugs, and other small molecules to form particles that are effective for delivery into a cell, tissue and/or organism either in vitro or in vivo. The presently disclosed polymers demonstrate differential cell-type specificity, an ability to promote endosomal escape to protect the cargos from degradation and enhance delivery to the cytoplasm, and/or bioreducibility, which enables triggered intracellular drug release to be tuned to promote optimal delivery to the target cell type. The presently disclosed materials may be used to treat a wide variety of conditions or diseases, such as cancer, cardiovascular diseases, infectious diseases, and ophthalmic diseases.
BIODEGRADABLE CATIONIC POLYMERS AND USES THEREOF
Disclosed herein are poly(hydroxylalkyleneimine disulfide)polymers, which have both desirable transfection properties and reduced toxicity.
CATECHOLAMINE-BASED MEMBRANE, PROCESS FOR ITS PREPARATION AND USES THEREOF
The present invention provides a process for preparing a self-standing catecholamine-based membrane, the process comprising the steps of: (a) cross-linking a catechol derivative with an amine selected from the group consisting of: a known aliphatic amine hydrocarbon of formula (II); and an aromatic amine of formula (IIbis), in a liquid medium, wherein both the catechol and the amine are soluble, at a pH comprised from 6.5 to 10, and under appropriate agitation to create a catecholamine membrane in the air/liquid interface in the absence of any support; and b) isolating the membrane resulting from step (a) from the air/liquid interface. The resulting self-standing catecholamine-based membrane was robust, easy to handle and manipulate, highly flexible and adaptable to any kind of surface without breaking, and adhesive. In addition, the free-standing membrane of the invention shows a Janus character, with an unexpected nanopatterning in the water-contact side which endows the membranes of the invention with a higher roughness surface, something of value to promote cell adhesion.
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A POLYMERIC CARRIER FOR DELIVERY OF A PAYLOAD TO A CELL
A polymeric carrier for delivery of a payload to a cell that can include poly(ethylenimine) and a biodegradable core molecule having disulfide bonds. The carrier can be used to introduce a therapeutic material for gene therapy or other therapeutic purposes.
FUNCTIONALIZED NANOMATERIALS
A functionalized nanomaterial, such as a nanoparticle, can include a polythioaminal functionalized surface. The polythioaminal linked to the surface of the nanomaterial can be bonded to a compound such as therapeutic and/or diagnostic materials. The thiol-based linkages can be used to bond the polythioaminal to both the nanomaterial and the therapeutic and/or diagnostic materials. Polythioaminals can be prepared via reactions of triazine and dithiols. Polythioaminals thus prepared can be further modified to provide linkages to the nanomaterial and other compounds such as medicinal compound, peptides, and dyes. Nanomaterials including such compounds linked thereto via the polythioaminal can be supplied for therapeutic and/or diagnostic purposes to biological target regions.