A signal indicative of sound detected by at least one sensor at an audio device is received. The audio device may at least partially covers a pinna and the detected sound may interact with at least a torso of a human body, but can also interact with the head and shoulder. The signal is modulated with a non-linear transfer function to generate a modulated signal indicative of one or more audio cues for spatializing the detected sound while the audio device at least partially covers a pinna. Sound is output by the audio device based on the modulated signal.

A system for predicting a likelihood of an occurrence of hallucinations in a subject including a master device configured to be at least one of moved, moved on, and manipulated by a subject, a slave device operably connected with the master device and adapted so that the subject is directly or indirectly touched by the slave device according with the master device's movement, a computer device operably connected to both the master and the slave device, the computer device configured to modulate at least one of a time, space, and force activation of the slave device in response to an activation of the master device, record data regarding a difference in at least one of time, space and force activation, compare the recorded data with reference data, and graphically or numerically showing the result of the comparison on a display device, as an indicator of the likelihood of the occurrence of hallucinations in a subject.

A method for assessing a cognition and movement disease or disorder in a subject suspected to suffer therefrom. A cognition and/or fine motoric activity parameter is determined from a dataset of activity measurements obtained from the subject using a mobile device. The determined activity parameter is compared to a reference, and the cognition and movement disease or disorder is assessed. Also disclosed is a method for identifying whether a subject will benefit from a therapy for a cognition and movement disease or disorder. The steps just described are performed along with the step of identifying the subject as one who benefits from the therapy if the cognition and movement disease or disorder is assessed. Also disclosed is a mobile device comprising a processor, at least one sensor, a database and software which is tangibly embedded in said device and, when running on said device, carries out the disclosed methods.

An example system for mitigating motion sickness within a vehicle is provided. The system includes a motion sickness mitigation device (MSMD) integrated into the vehicle and configured to generate electrical stimulation pulses upon actuation. The system also includes a controller operatively connected to the MSMD. The controller is configured to: obtain signals indicative of a potential motion sickness condition; determine whether a motion sickness conditions exists based on the signals; and, in response to determining that a motion sickness condition exists, actuate the MSMD.

A device for providing tactile stimulation of a subject via a pulse of compressible fluid, typically for medical diagnostic and therapeutic applications. The device preferably includes a high pressure fluid source and a low pressure fluid source. A pressure valve selectively connects the pressure sources to an outlet conduit. The outlet conduit includes an applicator for directing pulses against the skin of a subject. The pulses may be applied via one applicator or a plurality of applicators, and may be applied in one pattern or several patterns at various application sites. A method of providing tactile stimulation is also disclosed.

An image sensor in a first earcup captures an image of a pinna. First sound is output by a transducer in a second earcup located at the pinna and respective second sound is detected by each of one or more microphones in the second earcup located at the pinna. Based on the captured image and the respective second audio sound from each of the one or more microphones, a non-linear transfer function is determined which characterizes how sound is transformed by the pinna. A signal is generated indicative of one or more audio cues for spatializing third sound based on the determined non-linear transfer function.

The present invention provides a system for real-time pain detection, which comprises a means for acquiring biomedical signals relating to pain in a subject in need thereof, a computing means for transforming the acquired biomedical signals during a given period of time into the signal data for measurement of pain, analyzing the data to divide into two or more models, including at least a pain model which is defined by the data showing a peak-shaped profile and a non-pain model which is defined by the data showing a flat profile, whereby the pain status of the subject is measured based on the results of the analysis, a process means for generating an index of pain using the results of the analysis depending on the subject's demands or sensation, and a display showing the pain status of the subject.

A method for inducing the feeling of a presence (FoP) in a subject by using a master-slave robotic system, the method including the steps of altering a visual perception of a surrounding environment of the subject, connecting the subject with a robotic master device so that the subject can move, move on or manipulate the robotic master device, connecting the subject with a robotic slave device, making the subject move, move on or manipulate the robotic master device so that the subject is directly or indirectly touched by the robotic slave device according to a movement of the robotic master device, wherein the robotic master device and the robotic slave device are operatively connected so that the subject receives at least one of spatially and temporally conflicting sensorimotor stimulation.

A magnetic resonance imaging apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to specify a search start position of a matrix representing inter-regional connectivity between a plurality of regions in a brain based on a result of an analysis on an image of a subject and an attention degree set to each of the regions. The processing circuitry is configured to search the matrix using the search start position.

A device for providing tactile stimulation of a subject via a pulse of compressible fluid, typically for medical diagnostic and therapeutic applications. The device preferably includes a high pressure fluid source and a low pressure fluid source. A pressure valve selectively connects the pressure sources to an outlet conduit. The outlet conduit includes an applicator for directing pulses against the skin of a subject. The pulses may be applied via one applicator or a plurality of applicators, and may be applied in one pattern or several patterns at various application sites. A method of providing tactile stimulation is also disclosed.