Provided are methods and system for assessing a human subject's neurological and/or psychological status. The methods entail displaying visual tests to a human subject, wherein each of the visual tests includes a visual target signal, optionally with visual cue signals, for eliciting visual and, optionally, body part, movements by the subject. Following the display, the movements are then detected. The latency and/or correctness of such movements can then be used to assess the subject's neurological and/or psychological status. Also provided are methods and systems for assessing performance validity.

The disclosed systems and methods include displaying disease trigger icons within a disease trigger map in a GUI, where the disease trigger map corresponds to a particular disease symptom, and where the position and size of a particular trigger icon within the trigger map based one or more of (i) the degree or strength of a statistical association between the trigger icon's corresponding disease trigger and the disease symptom, and (ii) a cumulative frequency and/or amount of exposure to the trigger icon's corresponding disease trigger. Some embodiments also include displaying a patient population disease trigger map one or more relationships between (i) one or more disease triggers and (ii) one or more patients of the patient population. Some embodiments may further include facilitating communication and/or disease trigger information sharing among patients.

A controller-based apparatus for diagnosis and treatment of a subject with acquired brain injury and dysfunction. Various embodiments of the invention described herein recognize that different body postures affect the autonomic nervous system differently, and therefore various external stimuli may have different therapeutic efficacies when a patient or subject is in each body posture. Postures, such as walking, sitting, standing, prone and supine, have different effects on the autonomic nervous system, and therefore some stimuli have different physiological efficacies while a patient or subject is in a given body posture. Disclosed embodiments of the present invention leverage this relationship to provide a controller-based apparatus that determines a combination of posture and stimulus that has optimal therapeutic effect, while minimizing health practitioner involvement. The controller based apparatus provides a treatment that stimulates the nervous system through a combination of noninvasive therapies that stimulate brain cells to increase their efficiency—this promotes the formation of pathways that help transfer information throughout the brain in such a way that in the end, the affected area of the brain and overall brain function are improved without medication or surgery.

A system for controlling a body part includes a number of sensing devices that sense signals from a hemisphere of a brain. A signal translating unit translates the signals into a command signal for controlling the body part, which is on a same side of the body as the hemisphere of the brain. A prosthetic device receives the command signal from the signal translating unit and manipulates the body part in response to the command signal.

A video oculography (VOG) system for calculation and display of Corrective Secondary Saccades Analysis is disclosed and utilized in a method for Objective Diagnostics of Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy and Glissades. The method comprises the steps of using a VOG system to calculate corrective saccades. The VOG based system is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion and collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy are calculated.

One aspect of the present disclosure relates to a system that can identify a focal area of abnormal brain interactions in a subject. Time series data can be received that corresponds to recordings from a plurality of regions in a brain of the subject during a resting period. Based on the time series data, an information inflow associated with each of the plurality of regions can be determined. The focal area of the abnormal brain interactions can be identified as one of the plurality of regions having a maximum information inflow.

A stroke detection apparatus comprises a data processing device comprising a processor and at least one wearable sensor configured to generate movement data of at least a portion of the user's body. The data processing device is configured to process first movement data for a first movement and second movement data for a second movement received from the at least one wearable sensor. Wherein the data processing device is configured to determine asymmetry of user's movement based on the first and second movement data and generate a stroke detection signal in dependence on the determined asymmetry.

A method and system for detecting a possible stroke in a person through the analysis of voice data and image data regarding the gate of the user, facial features and routines, and corroborating any anomalies in one set of data against anomalies in another set of data for a related time frame.

Audio of a user speaking is gathered while spatial data of the face of the user is gathered. Positions of elements of the face of are identified, wherein relative positions of the elements cause a plurality of qualities of the user voice. A subset of positions of the elements are identified to have caused a detected first quality of the user voice during the period of time. Alternate positions of the one or more elements are identified that are determined to cause the user voice to have a second quality rather than the first quality. A graphical representation of the face that depicts one or more adjustments from the subset of the positions to the alternate positions is provided to the user.

The present invention provides systems and methods for detection and diagnosis of concussion and/or acute neurologic injury comprising a portable headwear-based electrode array and computerized control system to automatically and accurately detect cortical spreading depression and acute neurological injury-based peri-infarct depolarization (CSD/PID). The portable headwear-based electrode system is applied to a patient or athlete, and is capable of performing an assessment automatically and with minimal user input. The user display indicates the presence of CSD/PID, gauges its severity and location, and stores the information for future use by medical professionals. The systems and methods of the invention use an instrumented DC-coupled electrode/amplifier array which performs real-time data analysis using unique algorithms to produce a voltage intensity-map revealing the temporally propagating wave depressed voltage across the scalp that originates from a CSD/PID on the brain surface.