Systems, devices, and methods for remote monitoring and managing of patients with chronic pain are discussed. A remote monitoring system comprises a cloud-computing device and a remote device. The cloud-computing device receives patient data including physiological or functional information sensed by sensors, and provides on-demand cloud-based services including establishing a correspondence between one or more physiological or functional states and one or more pain levels, detecting patient physiological or functional state, predicting a pain level, detecting a patient behavior, generating a recommendation for adjusting sensor operations based on the patient behavior, and storing patient data and other information in a cloud storage. The remote device can access the cloud storage and the cloud-based services, provide the stored information to an authorized user or the patient, control an implantable device to initiate or adjust a neuromodulation therapy, or adjust sensor operations.

A diagnostic method for determining if a patient is viable candidate for a surgical procedure to permanently eliminate migraine headache pain. The method includes determining if a patient's pain is a migraine pain condition or pain from another medical condition and determining an anatomical location of the determined migraine pain condition. Once the anatomical location is determined, the method correlates the determined anatomical location of the migraine pain condition to a root cause nasal/sinus location and determines a root cause nasal/sinus condition that is causing the patient's migraine pain. Once these diagnostic procedures are complete, the patient may be scheduled for surgery to eliminate the root cause nasal/sinus condition, and thus, permanently eliminate the migraine headache pain.

A pain estimation apparatus includes: an information acquisition unit configured to perform a process for acquiring, in an endoscopic examination, examination state information for estimation including insertion state information for estimation including at least one of insertion shape information for estimation about an insertion shape of an insertion section of an endoscope inserted inside a body of a subject or operation force amount information for estimation about an amount of force applied to the insertion section, and information different from either of the insertion shape information for estimation and the operation force amount information for estimation; and a pain estimation processing means configured to generate pain information about pain of the subject based on the examination state information for estimation including the information different from either of the insertion shape information for estimation and the operation force amount information for estimation, and the insertion state information for estimation.

Methods for treating and managing pain in a patient with therapeutic neuromodulation and associated systems and methods are disclosed herein. Chronic or debilitating pain can be associated, for example, with a disease or condition of the abdominal or reproductive viscera. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a target blood vessel of a diseased or damaged organ of a patient experiencing pain. Targeted sympathetic nerve activity can be modulated at least along afferent pathways which can improve a measurable parameter associated with the pain of the patient The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the target sympathetic nerve.

Systems and methods for identifying a condition of a user. A treatment apparatus is configured to be manipulated by the user for performing an exercise, and an interface is communicably coupled to the treatment apparatus. One or more sensors are configured to sense one or more characteristics of an anatomical structure of the user. A processing device and a memory is communicatively coupled to the processing device. The memory includes computer readable instructions, that when executed by the processing device, cause the processing device to: receive, from the sensors, one or more sensor inputs representative of the one or more of characteristics of the anatomical structures; calculate an infection probability of a disease based on the one or more characteristics of the anatomical structures; and output, to the interface, a representation of the infection probability.

Methods for treating and managing pain in a patient with therapeutic neuromodulation and associated systems and methods are disclosed herein. Chronic or debilitating pain can be associated, for example, with a disease or condition of the abdominal or reproductive viscera. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a target blood vessel of a diseased or damaged organ of a patient experiencing pain. Targeted sympathetic nerve activity can be modulated at least along afferent pathways which can improve a measurable parameter associated with the pain of the patient The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the target sympathetic nerve.

A nerve stimulation system including a stimulation probe including a handle and a stimulation head at an end of the handle; a reference electrode; and a control system in communication with the stimulation probe and the reference electrode, the control system configured to generate an electrical stimulation signal that, when delivered to a skin surface of a patient using the stimulation probe, induces an activation potential in a plurality of nociceptors while remaining below a threshold that induces a muscle contractile response.

An endoscopic examination supporting apparatus includes at least one processor including hardware. The processor acquires insertion shape information indicating an insertion shape of an insertion section of an endoscope inserted into a subject, evaluates, based on the insertion shape information, a procedure including inserting operation for the insertion section performed by a user who operates the endoscope during an endoscopic examination, and generates procedure evaluation information.

Novel tools and techniques are provided for implementing intelligent assistance (“IA”) or extended intelligence (“EI”) ecosystem to placement procedures for cardiac implantable electronic device (“CIED”). In various embodiments, a computing system might analyze received one or more first layer input data (i.e., room content-based data) and received one or more second layer input data (i.e., patient and/or tool-based data), and might generate one or more recommendations for guiding a medical professional in performing a CIED placement procedure in a heart of the patient, based at least in part on the analysis, the generated one or more recommendations comprising 3D or 4D mapped guides toward, in, and around the heart of the patient. The computing system might then generate one or more XR images, based at least in part on the generated one or more recommendations, and might present the generated one or more XR images using a UX device.

A pain measurement and diagnostic system (PMD) for bioanalytical analysis of pain matrix activity and the autonomic nervous system to diagnose and validate patient treatments, health status and outcomes to diagnose and validate patient treatments and outcomes. The PMD is implemented using medical devices for measuring and reporting objective measurements of pain through patient monitoring and analyzing related biological, psychological, social, environmental, and demographic factors that may contribute to and effect physiological outcomes for patients and through the analysis, improve diagnosis of pain, the evaluation of related disease states, and treatment options.