Multi-state engagement with continuous glucose monitoring (CGM) systems is described. Given the number of people that wear CGM systems and because CGM systems produce measurements continuously, a platform that provides a CGM system may have an enormous amount of data. This amount of data is practically, if not actually, impossible for humans to process. In implementations, a CGM platform includes a data analytics platform that obtains packages of glucose measurements provided by a CGM system and also obtains additional data associated with a user. The data analytics platform generates state information for the user by processing these CGM packages and the additional data, at least in part, by using one or more models. Based on this state information, the data analytics platform controls communication with the user, which may include generating intervention strategies to prevent users from transitioning to a negative state such as discontinuing use of the CGM system.

Apparatus and methods are described including identifying that a subject suffers from sleep apnea. Positive airway pressure (PAP) is applied to the subject via a mask placed on a face of the subject. A respiratory-related parameter of the subject is sensed, while the mask is on the face of the subject, and a need of the subject for respiratory support is assessed, responsively to the respiratory-related parameter. In accordance with the assessed need, the mask is configured to regulate the PAP provided to the subject's face. Other applications are also described.

A method for determining an efficacy of medication treatment for a patient includes determining, by one or more processors, based on a local field potential (LFP) activity of the patient, when the patient takes medication and/or a duration of when the medication is effective. The method further includes outputting, by the one or more processors, an indication of when the patient takes the medication and/or the duration of when the medication is effective to facilitate a treatment for the patient.

An apparatus that includes a partial power source including a first material and a second material, the partial power source configured to generate, upon contact with a conducting medium, a potential difference between the first material and the second material to provide power to a control device, and generate, using the first material and the second material, a current flow within the conducting medium, the current flow including information encoded based on a variable conductance between the first material and the second material.

A portable system is provided for measuring an analyte, such as acetone, in the breath or other bodily fluid of a user. The system includes a portable measurement device that analyzes fluid samples and generates corresponding measurements. The portable measurement device communicates with an application which runs on a smartphone or other mobile device of the user, and the application reports measurement data to a remote system.

A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment, including either suspending or adjusting turn schedule based on various types of patient movement. Compliance with Head-of-Bed protocols can also be performed based on actual patient position instead of being inferred from bed elevation angle. The sensor can include bi-axial or tri-axial accelerometers, as well as resistive, inductive, capacitive, magnetic and other sensing devices, depending on whether the sensor is located on the patient or the support surface, and for what purpose.

An oral appliance includes an upper arch and a seal. The upper arch may be positioned proximate a maxillary dentition of a user. The upper arch includes a first tab and a second tab positioned on opposite sides of a plane substantially bisecting the upper arch. The seal defines a first receptacle and a second receptacle that may receive the first and second tabs to couple the seal to the upper arch and to inhibit breathing through a mouth of the user.

The present invention relates generally to systems, devices, and methods for tracking compliance of orthodontic appliance usage, and more specifically to systems, devices, and methods for tracking compliance of orthodontic appliance usage using a compliance device and/or a light therapy apparatus. The invention provides compliances device that can be configured to be disposed within a patient's mouth. In some embodiments, the compliance device can comprise a sensor configured to detect an input associated with whether an orthodontic appliance is at least partially disposed within the patient's mouth at a first time and at a second time, with the second time being subsequent to the first time.

The present invention has an object to manage the manual ingestion (and failure of manual ingestion) of an ingestible object without making the user feel bothered. The present invention includes: a collating unit configured to collate the biological data acquired by a biosensor and the temporal changes of biological data that occur after a medicine is taken and after a medicine is not taken at a medicine-taking timing; and a warning output unit configured to output, on the basis of a result of the collation, information on whether or not a living body has taken the medicine.

Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.