Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.

A method for administering an exposure treatment of a cognitive behavioral therapy (CBT) uses a mobile app and a server application. A user state of a patient undergoing a first step of the CBT based on the patient's condition during the first step is detected by sensors of the patient's smartphone. A situational state of the patient's surroundings during the first step is detected by the smartphone sensors. The mobile app determines whether the patient has made progress performing the first step. A user prompt is generated based on the user state and situational state. A next step of the CBT is configured based on the user state and situational state. The characteristics of the user prompt are generated using machine learning based on past task completions by the patient and other users so as to increase the likelihood that the patient will complete the next step of the CBT.

The present invention relates to a digital content-based method for providing therapeutics information, the method comprising: a first step of performing stimulation on a brain of a user to obtain fNIRS (functional near-infrared spectroscopy) data of the user; a second step of extracting a first brain activation area from a plurality of brain areas of the user using the obtained fNIRS data; a third step of determining a first brain state of the user, based on the first brain activation area; a fourth step of providing the user with a content determined corresponding to the first brain state determined in the third step under an XR (Extended Reality) environment; a fifth step in which the user performs a mission corresponding to the content; a sixth step of extracting a second brain activation area from the plurality of brain areas with reference to the fNIRS data of the user following performing the mission; and a seventh step of determining a second brain state of the user, based on the second brain activation area; an eighth step of determining information related to amelioration of the brain state of the user.

The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow, have improved energy storage requirements, enable improved LES function while concurrently delivering additional health benefits, and enable improved LES function post stimulation termination.

An exercise machine adjustable resistance system and method for efficiently varying the workout resistance for an exercise machine. The exercise machine generally includes a carriage movably positioned with respect to the at least one rail, a plurality of springs selectively connectable to the carriage to provide a resistance level to the carriage, a plurality of electrically actuated mechanical devices adapted to latch a corresponding one of the plurality of springs to the carriage when in the latch state and unlatch a corresponding one of the plurality of springs to the carriage when in the unlatch state and a control unit in communication with the plurality of electrically actuated mechanical devices to selectively control the state of each of the plurality of electrically actuated mechanical devices to be within the latch state or the unlatch state.

A system for modulating bladder function is disclosed. A system for evaluating the electrophysiological function of a bladder is disclosed. Methods for performing a controlled surgical procedure on a bladder are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. An implantable device for monitoring and/or performing a neuromodulation procedure on a bladder is disclosed.

A wearable health and lifestyle device including at least a measurement module configured to be worn by a user in at least a first wearing position, the measurement module comprising a 3-axis accelerometer unit configured to provide acceleration data and inclination data, a temperature measurement unit configured to provide temperature data, a light radiation measurement unit configured to provide light radiation data, said light radiation measurement unit comprising at least one multi-spectral sensor configured to measure wavelength bands over the range 290 nm to 1150 nm, a storage module configured to receive and store said acceleration data, said inclination data, said temperature data and said light radiation data, and an analysis module configured to analyze a data set comprising acceleration data, inclination data, temperature data and light radiation data.

The present disclose generally relates to systems and methods for active titration of one or more cranial or peripheral nerve stimulators to treat obstructive sleep apnea. The active titration can be accomplished in an automated fashion by a closed-loop process. The closed-loop process can be executed by a computing device that includes a non-transitory memory storing instructions and a processor to execute the instructions to perform operations. The operations can include defining initial parameters for the one or more cranial or peripheral nerve stimulators for a patient; receiving sensor data from sensors associated with the patient based on a stimulation with the one or more cranial or peripheral stimulators programmed according to the initial parameters; and adjusting the initial parameters based on the sensor data.

A method includes assigning, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively. Some of the locations are on an endocardial surface of the tissue, and others of the locations are on an epicardial surface of the tissue. The method further includes assigning respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values. Other embodiments are also described.

A state assessment system, a diagnosis and treatment system and a method for operating the diagnosis and treatment system are disclosed. An oscillator model converts a physiological signal of a subject into a defined feature image. A classification model analyzes state information of the subject based on the feature image. An analysis model outputs a treatment suggestion for the subject based on the state information of the subject. An AR projection device projects acupoint positions of a human body onto the subject, for the subject to be treated based on the treatment suggestion.