An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain a drug, a temporary seal closing the opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release a drug within the reservoir through the opening of the housing.

An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system monitors respiration based on oxygen saturation readings from a fingertip pulse oximeter in communication with a smart mobile device and sends opioid monitoring information from the smart mobile device to an opioid overdose monitoring service. The opioid overdose monitoring service notifies a first set of contacts when the opioid monitoring information.

Systems and methods to determine if an individual is impaired. The system includes a display and a stimulus on the display. The system include a controller that is programmed to move the stimulus about the display and one or more sensors that track eye movements and pupil size of a user due to movement of the stimulus or light conditions. The system includes a processor programmed to analyze the eye movements and pupil data size. The method includes using a testing apparatus and collecting data from the testing apparatus. The method includes storing the collected data. The method includes processing the data with an automated impairment decision engine to determine whether a test subject is impaired. The method may include using machine learning models or statistical analysis to determine whether a test subject is impaired. The automated impairment decision engine may be trained using machine learning and/or statistical analysis.

A vehicle includes a processing device that detects an authentication device approaching the vehicle, determines a user's impaired state based on user condition information acquired using at least one device mounted on the vehicle, and performs a safe driving assistance service. The safe driving assistance service can prevent an impaired user from operating the vehicle.

A system and method of deploying an ignition interlock system. The method comprises identifying a wearable transdermal device in response to initiating wireless communication between a controller device of a vehicle system and the wearable transdermal device; receiving a transdermal alcohol measurement transmitted from the wearable transdermal device; and generating, in accordance with the transdermal alcohol measurement being above a predetermined intoxication threshold, a vehicle ignition lockout state of the vehicle system.

The present invention provides a novel, comprehensive approach for the effective, safe and compassionate management of pain and opioid dependency, both in inpatient and outpatient settings, through the various stages of patient contact with the current healthcare system (e.g. initial encounter, treatment initiation, inpatient care, discharge, and post-discharge/chronic management) via innovative methods and treatment algorithms that provide consistent, repeatable and material advances in potential and high-risk, opioid-dependent patient management.

A method and system for monitoring a user's intoxication including receiving a set of signals, derived from a set of samples collected from the user at a set of time points; providing a sobriety task to the user proximal to a time point of the set of time points; generating a performance dataset characterizing performance of the sobriety task by the user; receiving a supplementary dataset characterizing a demographic profile of the user and/or a physiological state of the user; determining a set of values of an intoxication metric, derived from the set of signals; generating a predicted temporal profile of the intoxication metric for the user based upon the set of values, the set of time points, and the supplementary dataset; generating an analysis of the user's sobriety based upon the performance dataset and the predicted temporal profile; and providing a notification to the user based upon the analysis.

An electrochemical sensor arrangement (10) for a breath alcohol measuring device (100), to a corresponding breath alcohol measuring device (100) as well as to a process for determining a vitality of electrodes of an electrochemical sensor. The electrochemical sensor arrangement comprises an electrochemical sensor with at least two electrodes (12, 14). The electrochemical sensor arrangement further comprises a heat source (16). The heat source is arranged such that it, upon activation, selectively heats one of the electrodes (12) of the electrochemical sensor.

A drug overdose detection apparatus that is configured to measure the blood oxygen level of a user and upon detection in a drop thereof provide administration of a substance to counteract the drug overdose. The present invention includes a housing that is configured to be worn by a user has an interior volume. Disposed in the interior volume of the housing is a substance administration assembly wherein the substance administration assembly includes a syringe member, a plunger member and a plunger driver. A motor is operably coupled to the plunger driver and facilitates movement thereof. A spring needle assembly is operably coupled to the substance administration assembly and includes a spring biased needle that is operable to inject into a patient so as to inject the substance. The present invention further includes an audio alarm and transceiver configured to provide alerts and transmit signals.

In an example, a method of detecting cyanide exposure of an individual includes: measuring a thiocyanate level of the individual which includes placing saliva of the individual in contact with a chemical indicator to measure the thiocyanate level and measuring thiocyanate (SCN.sup.−) catalyzed by enzyme rhodanese of the individual; comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of cyanide poisoning for which a medical procedure is recommended to manage health effects of the exposure; and performing the medical procedure if the measured thiocyanate level is above the preset thiocyanate threshold and not performing the medical procedure if the measured thiocyanate level is not above the preset thiocyanate threshold.