A processor searches for a first similar case from among a plurality of reference cases, each of the plurality of reference cases including at least one diagnosed image and a diagnosis log, the diagnosis log describing a treatment method performed on a diagnosed patient for whom the diagnosed image is acquired and a treatment result obtained by the treatment method, the first similar case having a similar feature to a target image obtained by imaging a treatment target patient who is to be treated, the first similar case including, as the diagnosed image, a post-treatment image obtained through imaging after treatment. The processor further searches for a second similar case from among the plurality of reference cases, the second similar case having a similar feature to the post-treatment image included in the first similar case. Further, the processor presents the treatment method and the treatment result described in a search diagnosis log that is the diagnosis log included in each of the first similar case and the second similar case.

The present disclosure relates to establishing bidirectional communication between a brain wave processing device and a vehicle to control at least one vehicle component of the vehicle. For this purpose, a brain-computer communication channel is provided between the brain wave processing device and the respective vehicle component. Subsequently, a control signal is determined as a function of a brain wave of the operator of the brain wave processing device and transmitted via the brain-computer communication channel to adapt at least one operating parameter of the respective vehicle component. This causes a change in the operating state of the respective vehicle component. Depending on this, an output signal is generated and is assigned to the change in the operating state of the vehicle component. This output signal is transmitted back to the brain wave processing device via the brain-computer communication channel and is output to the operator by means of an output unit of the brain wave processing device.

A system includes a processor circuit configured to receive an endovascular flow measurement obtained by an endovascular flow measurement positioned within a blood vessel of a patient. The system controls a nerve stimulation device to stimulate a nerve of the patient and receives an additional endovascular flow measurement while the nerve is stimulated. The processor circuit then performs a comparison of the two flow measurements received and provides an output based on the comparison.

Pharmaceutical compositions containing tetrathiomolybdate (TTM) are disclosed. Pharmaceutical compositions and formulations that contain TTM along with other co-drugs, such as diethylcarbamazine (DEC) and astaxanthin (ATX), are also disclosed. Formulations include a delayed release oral form that releases the TTM in the gastrointestinal tract after the oral form passes the stomach, and an enteric oral form that is not a delayed release form are disclosed. Methods of treating cancer, treating cancer patients as an adjuvant therapy, and treating pulmonary arterial hypertension by administering the pharmaceutical compositions are further disclosed.

A method and system is provided for determining a discrimination index in a subject that may be suffering from or at risk for a stress-induced psychiatric disorder. The discrimination index may be equal to a ratio of a subject's cued fear response and non-cued fear response measured during a fear-potentiated startle (FPS) paradigm. Such a value may allow a physician or researcher to quantify how well a subject discriminates between signaled (cued) fear and un-signaled (non-cued) fear, which may be a biomarker for psychiatric disorders like post-traumatic stress disorder, panic disorder, phobias, and/or generalized anxiety disorder. The determined discrimination index may provide a standardized way of diagnosing and evaluating mental illnesses, more uniform treatment of patients, and/or more precise monitoring and evaluation of treatment efficacy.

A virtual or augmented reality system is disclosed which is capable of both (i) evaluating prospective implantable neurostimulator patient candidates, and (ii) determining optimal stimulation settings for already-implanted neurostimulation patients. Physiological sensors are included with the system to provide objective measurements relevant to a patient's symptoms, such as pain in a Spinal Cord Stimulation (SCS) system. Such objective measurements are determined during the presentation of various virtual or augmented environments, and can be useful to determining which patients are suitable candidates to consider for implantation. Stimulation settings for already-implanted patients may be adjusted while presenting a virtual or augmented environment to the patient, with objective measurements being determined for each stimulation setting. Such objective measurements can then be used to determine optimal stimulation settings for the patient.

Embodiments herein relate to systems, devices and methods for managing pharmacological therapeutics and aspects of the same. In an embodiment, a hearing assistance device can include a control circuit, an electroacoustic transducer for generating sound in electrical communication with the control circuit, a power supply circuit in electrical communication with the control circuit, and a sensor package in electrical communication with the control circuit. The control circuit can be configured to evaluate a signal from at least one of the sensors of the sensor package to detect administration of a therapy or receive data indicating that administration of a therapy has taken place. The control circuit can also be configured to record an instance of a detected medication administration event along with a timestamp. Other embodiments are also included herein.

A measurement device for a vehicle seat includes a memory; a processor coupled to the memory; a headrest body of a headrest; a first side section of the headrest that is swingable toward a seat front side so as to support the neck of the vehicle occupant; a second side section of the headrest that is swingable toward the seat front side so as to support the neck of the vehicle occupant; a first electrode provided at the first side section and contacting the neck in a state in which the first side section is supporting the neck; and a second electrode provided at the second side section and contacting the neck in a state in which the second side section is supporting the neck. The processor is configured to acquire a waveform of a potential difference based on the potential difference between the first electrode and the second electrode over time.

A lead body is operable to be implanted proximate a target nerve tissue of a patient. A sensing electrode is configured to sense biopotentials over a first partial circumference of the lead body. A stimulation electrode is configured to deliver stimulation energy over a second partial circumference of the lead body. A signal generator is electrically coupled to the stimulation electrode and a sensing circuit is coupled to the sensing electrode. A processor is operable to apply a stimulation signal to the stimulation electrode via the signal generator and, via the sensing circuit, sense an evoked response to the stimulation signal that propagates along a neural pathway.

An artificial tongue is provided. The artificial tongue includes tongue tissue formed by a bioprinting process, an antenna embedded within the tongue tissue and configured to wirelessly receive power from an external device, a processor embedded within the tongue tissue and operatively coupled to the antenna, and a piezoelectric element embedded within the tongue tissue and operatively coupled to the processor. The piezoelectric element is configured to deform in response to an applied electric bias, and the processor is configured to cause the electric bias to be applied to the piezoelectric element based on the power received by the antenna.