A system that determines one or more sleep phenotyping parameters of a subject. In one embodiment, the system comprises a sleep sensor, a stimulus generator, and a processor. The sleep sensor generates signals that convey information related to the physiological functions that indicate the sleep stage of the subject. The stimulus generator provides a stimulus to the subject that enables information related to the sleep phenotyping parameters to be determined. The processor receives the signals generated by the sleep sensor and is in operative communication with the stimulus generator. The processor (i) determines, based on the signals received from the sleep sensor, whether a trigger condition related to the current sleep stage of the subject is satisfied, (ii) controls the stimulus generator to provide the stimulus to the subject if the trigger condition is satisfied, and (iii) quantifies the response of the subject to the stimulus.

Provided are methods and system for assessing a human subject's neurological and/or psychological status. The methods entail displaying visual tests to a human subject, wherein each of the visual tests includes a visual target signal, optionally with visual cue signals, for eliciting visual and, optionally, body part, movements by the subject. Following the display, the movements are then detected. The latency and/or correctness of such movements can then be used to assess the subject's neurological and/or psychological status. Also provided are methods and systems for assessing performance validity.

The present disclosure relates to methods and tools for enhancing cognition and improving well being in an individual. The methods involve presenting to an individual a task to be performed, presenting to the individual an interference, and receiving inputs from the individual. Where the interference is a distraction, the individual is to ignore the interference. Where the interference is an interrupter, the individual is instructed to respond to the interrupter as a secondary task and is said to be multi-tasking. Inputs are then also received from the individual pertaining to this secondary task. The methods encompass iterations of these presentating steps and receiving of the input, and generation of analysis and/or feedback to the individual. The methods can further include conducting an analysis and/or generating feedback to the individual. The analysis can include a comparison of the performances with or without each type of interference.

Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including a head mounted display to monitor one or more physiologic signals from the face or head of the subject is disclosed. A method for analyzing an ocular parameter of the subject to determine a sympathetic and a parasympathetic outflow thereto is disclosed.

A controller-based apparatus for diagnosis and treatment of a subject with acquired brain injury and dysfunction. Various embodiments of the invention described herein recognize that different body postures affect the autonomic nervous system differently, and therefore various external stimuli may have different therapeutic efficacies when a patient or subject is in each body posture. Postures, such as walking, sitting, standing, prone and supine, have different effects on the autonomic nervous system, and therefore some stimuli have different physiological efficacies while a patient or subject is in a given body posture. Disclosed embodiments of the present invention leverage this relationship to provide a controller-based apparatus that determines a combination of posture and stimulus that has optimal therapeutic effect, while minimizing health practitioner involvement. The controller based apparatus provides a treatment that stimulates the nervous system through a combination of noninvasive therapies that stimulate brain cells to increase their efficiency—this promotes the formation of pathways that help transfer information throughout the brain in such a way that in the end, the affected area of the brain and overall brain function are improved without medication or surgery.

A smart mirror can show live or recorded streaming video of an instructor performing a workout in a package that is attractive and unobtrusive enough to hang in a living room. The smart mirror includes a mirror surface with a fully reflecting section and a partially reflecting section. A display behind the partially reflecting section shows the video when the smart mirror is on and is almost invisible when the smart mirror is off. The smart mirror also has a speaker, a microphone, and a camera to enable a user to view the video content and interact with the instructor. The smart mirror may connect to the user's smart phone, a peripheral device (e.g., a Bluetooth speaker) to augment user experience, a biometric sensor to provide biometric data to assess user performance, and/or a network router to connect the smart mirror to a content provider, an instructor, and/or other users.

A relationship relating a load of exercise and a user's aerobic capacity may be determined as follows. A processor circuit of a device may retrieve, from a memory, a prior probability distribution of the load of exercise and a prior probability distribution of the user's aerobic capacity. The processor circuit may compute a joint prior probability of the load of exercise and the user's aerobic capacity. The processor circuit may compute a joint likelihood of the load of exercise and the user's aerobic capacity based on data indicative of a measured time-stamped work rate and a measured time-stamped heart rate. The processor circuit may combine the joint prior probability and the joint likelihood to produce a joint posterior probability. The processor circuit may use the joint posterior probability to determine a relationship relating the load of exercise and the user's aerobic capacity and output a calorie calculation.

The invention is measurement of two categories of medical attributes that proceed the causes previously measured to cause lower musculoskeletal (MSK) injuries including stress fractures. The innovation is the measurement of increase in the risk for lower musculoskeletal (MSK) injuries, including stress fractures, due to genetic factors that cause disease (pre-cursors of the disease) as an independent cause for an increase in the risk of MSK injuries, and the diseased states themselves as a cause of increased risk for lower MSK injuries. The method to be used for this measurement will be through statistical and quasi-experimental design. The innovation of measuring the genetic pre-cursor of diseases and these diseases themselves includes them as antecedents for the previously measured causes of stress fractures; such as biomechanical and anatomical factors; muscle power; muscle, ligament and tendon flexibility; equipment used; nutritional; bone mineral density; smoking; amenorrhea; estrogen, among others.

Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin of a patient or the surface of a structure such as a building or a bridge.

A biological information analysis device including: an indicator extraction unit that is configured to extract, from time-series data regarding blood pressure waveforms consecutively measured by a sensor that is configured to be worn on a body part of a user and to be capable of non-invasively measuring a blood pressure waveform for each heartbeat, data regarding blood pressure waveforms corresponding to a period of time in which a change in blood pressure occurs, and extract an indicator that is related to the functionality of respiratory organs of the user, based on characteristics of the blood pressure waveforms corresponding to the period of time; and a processing unit that performs processing that is based on the indicator thus extracted.