A tissue property sensing system includes a sensing assembly that is movable along a drive screw and includes an outer shaft, an anvil, a center drive, a piston, and a tension spring. The piston includes a distal arm having a distal portion and a head that extends from the distal portion. The piston is movable within the outer shaft to move the head in relation to the anvil between an open configuration and a closed configuration, wherein in the closed configuration, the head of the piston and the anvil are positioned to clamp and occlude flow of blood within tissue. The tension spring is coupled to the center drive and to the piston to urge the piston towards the center drive and to urge the head of the piston towards the anvil.

At least partial function of a human limb is restored by surgically removing at least a portion of an injured or diseased human limb from a surgical site of an individual and transplanting a selected muscle into the remaining biological body of the individual, followed by contacting the transplanted selected muscle, or an associated nerve, with an electrode, to thereby control a device, such as a prosthetic limb, linked to the electrode. Simulating proprioceptive sensory feedback from a device includes mechanically linking at least one pair of agonist and antagonist muscles, wherein a nerve innervates each muscle, and supporting each pair with a support, whereby contraction of the agonist muscle of each pair will cause extension of the paired antagonist muscle. An electrode is implanted in a muscle of each pair and electrically connected to a motor controller of the device, thereby simulating proprioceptive sensory feedback from the device.

A medical device system is configured to guide implantation of a pacing electrode for left bundle branch pacing. The system includes a medical device having a processor configured to receive at least one cardiac electrical signal, determine a feature of the cardiac electrical signal, compare the feature to left bundle branch signal criteria, and determine a left bundle branch signal in response to the feature meeting the left bundle branch signal criteria. The system includes a display unit configured to generate a user feedback signal indicating advancement of a pacing electrode into a left portion of a ventricular septum in response to the processor determining the left bundle branch signal.

A medical device system is configured to guide implantation of a pacing electrode for left bundle branch pacing. The system includes a medical device having a processor configured to receive at least one cardiac electrical signal, determine a feature of the cardiac electrical signal, compare the feature to left bundle branch signal criteria, and determine a left bundle branch signal in response to the feature meeting the left bundle branch signal criteria. The system includes a display unit configured to generate a user feedback signal indicating advancement of a pacing electrode into a left portion of a ventricular septum in response to the processor determining the left bundle branch signal.

Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.

Various methods and systems are provided for a fabric cover including a plurality of integrated electrodes for measuring an electrocardiogram signal of a patient in direct contact with at least a subset of the plurality of integrate electrodes. As one example, a fabric cover for an infant incubator or warmer includes a plurality of electrodes spaced apart from one another within a measurement area of a surface of the fabric cover adapted to have direct contact with a patient, the plurality of electrodes including a topmost electrode extending across an entire width of the measurement area, a bottommost electrode extending across the entire width of the measurement area, and a set of electrodes arranged between the topmost electrode and bottommost electrode, in a direction perpendicular to the width, within the measurement area.

A system, a method and a computer program product for automated detection and recognition of adverse events for monitoring the state of health of an individual

Systems and methods for monitoring patients with respiratory diseases are described. A system may include a sensor circuit to sense a respiration signal and at least one hemodynamic signal. The system may detect a specified respiratory phase from the respiration signal, and generate from the hemodynamic signal one or more signal metrics that are correlative to at least one of a systolic blood pressure, a blood volume, or a cardiac dimension. The system may detect a restrictive or obstructive respiratory condition when the hemodynamic signal metric indicates hemodynamic deterioration during a specified respiratory phase. The system may additionally classify the detected restrictive or obstructive respiratory condition into one of two or more categories, and deliver a therapy based on the detection or the classification.

The invention includes conductive polymeric coatings, medical device, coating solutions and methods of making the same. A coating solution for forming a conductive polymer layer can include a conductive monomer, at least one photoreactive component comprising an anionic photoreactive cross-linking agent or an anionic photoreactive hydrophilic polymer, and a solvent. A medical device can include an electrode and an electrically conductive coating disposed over the electrode. The electrically conductive coating can include a reaction product of the conductive monomer and the at least one photoreactive component. Other aspects are included herein.

A device to emit ultrasounds to wireless recharge an electronic device, wherein the emitting device includes at least one ultrasonic transducer and an electronic circuit to control the ultrasonic transducer, wherein the control electronic circuit is configured to: apply to the transducer an excitation electric signal in order to induce the emission of an ultrasonic wave towards the electronic device; and read a feedback electric signal generated by the transducer under the action of a part of the ultrasonic wave reflected by the electronic device, wherein the control electronic circuit comprises a feedback loop configured to adjust the frequency of said ultrasonic wave, so that the energy of said reflected part of the ultrasonic wave tends to a minimum value.