Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the devices include a membrane that has an interference domain designed to reduce the permeation of one or more interferents.

A method for processing a neural measurement obtained in the presence of artifact, in order to detect whether a neural response is present in the neural measurement. A neural measurement is obtained from one or more sense electrodes. The neural measurement is correlated against a filter template, the filter template comprising at least three half cycles of an alternating waveform, amplitude modulated by a window. From an output of the correlating, it is determined whether a neural response is present in the neural measurement.

A device for retarding birth including an upper ring for surrounding a cervix, an anchoring component for anchoring the device, and an elastic component for attaching the upper ring to the anchoring component, wherein the elastic component pushes the upper ring and the anchoring component apart. A device for retarding birth including a sleeve for surrounding a cervix along a greater portion of a length of the cervix, a support strip on the sleeve directed along an axis of the sleeve, and a ring at least partially around the sleeve, in which when a top of the sleeve is pushed to expand radially, the support strip pivots on the ring, such that an end of the support strip near the top of the sleeve moves radially outward, and an end of the support strip near the bottom of the sleeve moves radially inward. Related apparatus and methods are also described.

A surgical device for providing haptic feedback includes a housing having a cavity defined therein configured to receive a finger of a user and an elongated shaft configured to extend through the housing and into the cavity and configured to support a spring thereon and a pressure contact. A fluid-filled sensor is included that has a plurality of tubes configured to extend from the cavity, each tube includes a fluid-filled bladder at both ends thereof joined by a fluid channel therebetween. Each tube is configured to contain a fluid therein such that when a user's finger is engaged between the fluid-filled bladder at the proximal end of the tubes and the pressure contact, changes in pressure in the fluid-filled bladders at a distal end of the tubes is correspondingly registered in the fluid-filled bladders at the proximal end of the tubes providing haptic feedback to the user.

A cover for covering an oral device that includes a first sheet member made of a first resin, and a second sheet member made of a second resin and facing the first sheet member, wherein when a first direction is a direction along a surface of the first sheet member and a second direction is a direction along the surface of the first sheet member and orthogonal to the first direction, the first sheet member and the second sheet member are joined to each other in a bag shape so as to define an opening at a first side in the first direction. A protruding portion protrudes from the second sheet member and past an outer edge of the first sheet member at the opening in the first direction.

The disclosure provides an optical probe comprising an optical waveguide attached to a molecular switch that produces an altered optical signal upon binding a target molecule. The disclosure also provides an optical sensor system comprising an optical probe, a light source configured to emit the excitation light to be coupled into the optical waveguide of the optical probe; and a detector.

Embodiments provide a sensor insertion tool (SIT) that provides a motive force for insertion of an analyte sensor into/through skin. A SIT may be releasably locked to one or more components of a sensor insertion system, such that components of the sensor insertion system remain securely coupled during sensor insertion. A SIT may include a release member that unlocks or uncouples the SIT and the other components after sensor insertion. In various embodiments, a SIT may be a component of a sensor insertion system configured for assembly by an end user, a health care professional, and/or a caretaker prior to sensor insertion, and may act in cooperation with other sensor insertion system components. Additional components and methods of assembly and use are also provided herein.

Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

A personal wearable EEG monitor comprising an implantable electrode part with at least two electrodes (2,3) for measuring an EEG signal of a person. The electrode part comprises an electronic circuit arranged in a housing (1) with each electrode arranged external to the housing. The electrode part comprises a testing circuit for testing functionality of the electrode part. The testing circuit comprises a capacitor (9) coupled in serial connection to at least one of the electrodes, and a test signal generator for providing a test signal. The EEG monitor is adapted for analyzing the signal resulting from the signal generator for identification of faults in the electrode part. The invention further provides a method for detecting a leak current in an implanted EEG monitor part.

A method for measuring a neural response to a stimulus. Measurement circuitry is settled prior to a stimulus, by connecting a sense electrode to the measurement circuitry to allow the measurement circuitry to settle towards a bio-electrically defined steady state. Charge is recovered on stimulus electrodes by short circuiting the stimulus electrodes to each other. An electrical stimulus is then applied from the stimulus electrodes to neural tissue, while keeping the sense electrode disconnected from the measurement circuitry. After the stimulus, a delay is imposed during which the stimulus electrodes are open circuited and the sense electrode is disconnected from the measurement circuitry and from the stimulus electrodes. After the delay, a neural response signal present at the sense electrode is measured by connecting the sense electrode to the measurement circuitry.