An object is illuminated from at least one illuminating direction. For each illuminating direction, an intensity image of the object is captured during the illumination. On the basis of the at least one intensity image, a phase contrast image of the object is generated.

Disclosed is a way to provide a medical image processing device that may include a hardware processor that calculates at least one of trabecular connectivity, trabecular width, trabecular number, mineralization degree, osteoid volume, cortical width, and cortical porosity as a bone characteristic indicator of a subject from reconstructed image data generated from moiré image data acquired by photographing the subject.

Apparatus and methods are described including an endoluminal device configured to move along a portion of a lumen of a subject's body, an extraluminal imaging device, and at least one computer processor. While the endoluminal device moves along the portion of the lumen, a display displays an extraluminal image of the lumen in which a first indication of a location of the lumen is shown. The extraluminal imaging device acquires a sequence of extraluminal images of the endoluminal device moving along the portion of the lumen. The indication of the location of the lumen that is displayed is updated based upon the acquired sequence of extraluminal images, and the acquired sequence of images is displayed with the updated indication of the location of the lumen overlaid upon the images. Other applications are also described.

A switchable grating for phase contrast imaging comprising a reservoir with a medium and x-ray absorbing particles acoustically connected to a first ultrasound generator and a second ultrasound generator arranged along a side of the reservoir orthogonal to the first side. The ultrasound generators are each, individually or together, configured to generate a soundwave with a frequency and phase such that a standing wave is formed within the medium causing the x-ray absorbing particles to organize along pressure nodes of the standing waves.

An improved X-ray imaging system. The system comprises an X-Ray radiation source configured to emit an X-ray beam towards an object to be imaged and an X- ray detector configured to detect X-rays which have passed through the object. It further comprises a reconstruction processing means configured to reconstruct an image of the object based on the detected X-rays, wherein the reconstruction processing means is further configured to determining presence of at least one foreign object located in the object or located between a surface of the object and the X-Ray radiation source and/or the X-ray detector, obtaining a three-dimensional profile of the determined foreign object from a server-based foreign object database, and reconstructing an image of the object by acquiring a plurality of projection images of the object from the X-ray detector and reducing impact on image quality of an artefact that can be caused by the foreign object in the image of the object based on at least the obtained three-dimensional profile of the foreign object.

The present disclosure relates to a multi-spectrum X-ray grating-based imaging system and imaging method. The multi-spectrum X-ray grating-based imaging system according to the present disclosure comprises an incoherent X-ray source for emitting X-rays to irradiate an object to be detected, a grating module comprising a first absorption grating and a second absorption grating which are disposed in parallel to each other and are sequentially arranged in an X-ray propagation direction, and an energy-resolved detecting device for receiving the X-rays that have passed through the first absorption grating and the second absorption grating. One of the first absorption grating and the second absorption grating performs phase stepping actions within at least one period; during each phase stepping action, the incoherent X-ray source emits X-rays to irradiate the object to be detected; the energy-resolved detecting device receives the X-rays and performs spectrum identification of the X-rays; and after a series of phase stepping actions and data acquisitions over a period, at each pixel on the energy-resolved detecting device, X-ray intensities in each energy range are represented as an intensity curve.

A phantom material may be irradiated with varying energy x-rays to determine its phase shift properties. A determination of the difference between those phase shift properties and the phase shift properties of another material of interest can be represented and stored in terms of a polynomial function. The stored function can then be used in combination with a surrogate phantom shaped in the form of another object to obtain the phase shift properties of that other object as if it were made from the material of interest.

An accurate non-destructive inspection of a moving subject is conducted using a radiation source unit that irradiates radioactive rays toward gratings. Each grating includes a plurality of grating members. A radioactive ray detector unit detects the radioactive rays diffracted by the plurality of grating members. The plurality of grating members are arranged with a predetermined phase difference such that moiré pattern images respectively formed by the radioactive rays transmitted through first to third partial areas have a phase difference between the moiré pattern images.

The invention relates to a system and a method for active grating position tracking in X-ray differential phase contrast imaging and dark-field imaging. The alignment of at least one grating positioned in an X-ray imaging device is measured by illuminating a reflection area located on the grating with a light beam, and detecting a reflection pattern of the light beam reflected by the reflection area. The reflection pattern is compared with a reference pattern corresponding to an alignment optimized for X-ray differential phase contrast imaging, and the X-ray imaging device is controlled upon the comparison of the reflection pattern and the reference pattern.

An x-ray phase contrast imaging apparatus and method of operating the same. The apparatus passes x-rays generated by an x-ray source through, in succession, a source grating, an object of interest, a phase grating, and an analyzer grating. The x-ray source, the source grating, the phase grating, and the analyzer grating move as a single entity relative to an object of interest. The phase grating and the analyzer grating remain in fixed relative location and fixed relative orientation with respect to one another. The detected x-rays are converted to a time sequence of electrical signals. In some cases, the apparatus is controlled, and the electrical signals are analyzed by, by a general purpose programmable computer provided with instructions recorded on a machine readable medium. One or more x-ray phase contrast images of the object of interest are generated, and can be recorded or displayed.