In certain embodiments, a method includes accessing, in response to a first user input and via a storage system, digital animal records that include animal data (including inventory and health data) for animals; and generating, according to the inventory data, an inventory user interface (UI) that includes identifying information of a first portion of the animals. The method includes accessing, in response to a second user input and via the storage system, the health data and generating, according to the health data, a health records UI for managing the health records and that includes medical records of a second portion of the animals. The method includes receiving, via the inventory UI, inventory update data and, in response, transmitting an inventory update to the storage system. The method includes receiving, via the health records UI, health records update data and, in response, transmitting a health records update to the storage system.

Methods and apparatus for the application of reinforcement learning to animal medical diagnostics. In one embodiment, a system is disclosed that utilizes two (2) RL agents that are arranged sequentially and that are optimized independently from one another. The first RL agent is an assessment RL agent which takes as input from one or more of: outputs from classification artificial intelligence (AI) engines; outputs from subjective biological data storage devices, and outputs from objective biological data storage devices. Using these input(s), the assessment RL agent outputs a set of assessments which evaluate a set of conditions associated with an animal. This set of assessments is then provided as input to a second RL agent known-as a plan RL agent which determines a set of treatment recommendations and diagnostics based off this determined set of assessments. Methods and computer-readable media are also disclosed.

A musculoskeletal stabilization system adapted to stabilize spine and SI joint structures. The musculoskeletal stabilization system includes a spine structure stabilization sub-system and a pelvic structure stabilization sub-system. The pelvic structure stabilization sub-system comprising two multi-function prostheses that are adapted to be delivered to and inserted into SI joints of a subject via a posterior trajectory. The multi-function joint prostheses are further adapted to stabilize respective SI joints and cooperate with the spine stabilization sub-system to also stabilize the subject's spine jointly.

The invention provides methods for diagnosing coronary heart disease in a subject in need thereof comprising administering an admixture comprising CO2 to a subject to reach a predetermined PaCO2 in the subject to induce hyperemia, monitoring vascular reactivity in the subject and diagnosing the presence or absence of coronary heart disease in the subject, wherein decreased vascular reactivity in the subject compared to a control subject is indicative of coronary heart disease. The invention also provides methods for increasing sensitivity and specificity of BOLD MRI.

An imaging system that is configured to automatically obtain and provide two and three-dimensional digital images of various types of objects (e.g., tissue specimens, animals, electrical devices, etc.) for use in analysis thereof in a manner free of manual repositioning of the objects between images and free of movement of an electromagnetic radiation source and detector within or relative to a cabinet housing of the system.

An x-ray imaging apparatus for producing an x-ray image of an object, includes a support frame to which an x-ray source and an x-ray detector are connected. The x-ray source and the x-ray detector define between them an object space for the object to be examined. The x-ray source is configured to emit from a focal spot an x-ray beam with a main direction into the object space. The x-ray detector includes an array of pixels sensitive to the x-ray radiation. The x-ray imaging apparatus further includes a collimator arranged in proximity to the x-ray source and in the path of the x-ray beam between the x-ray source and the object to be examined. The collimator includes one or more collimator bodies defining a plurality of passages of the collimator, the passages having respective central directions defining a common focal point of the collimator on the side of the x-ray source, preferably a 2D array of passages seen in a plane perpendicular to the main direction of the x-ray beam.

A stationary in-vivo grating-enabled micro-CT (computed tomography) architecture (SIGMA) system includes CT scanner control circuitry and a number of imaging chains. Each imaging chain includes an x-ray source array, a phase grating, an analyzer grating and a detector array. Each imaging chain is stationary and each x-ray source array includes a plurality of x-ray source elements. Each imaging chain has a centerline, the centerlines of the number of imaging chains intersect at a center point and a first angle between the centerlines of a first adjacent pair of imaging chains equals a second angle between the centerlines of a second adjacent pair of imaging chains. A plurality of selected x-ray source elements of a first x-ray source array is configured to emit a plurality of x-ray beams in a multiplexing fashion.

Methods are described for conducting minimally invasive medical interventions utilizing instruments and assemblies thereof to stabilize and/or fixate a dysfunctional sacroiliac (SI) joint. In one embodiment, a drill assembly is advanced from a posterior approach into the SI joint to create a pilot SI joint opening; portions of which being disposed in the sacrum and ilium bone structures. After the pilot SI joint opening is created, a SI joint prosthesis is inserted into the pilot SI joint opening, wherein the SI joint prosthesis is positioned in the dysfunctional SI joint at a distance of at least 3.0 mm away from the SI joint dorsal recess.

Systems are described for conducting minimally invasive medical interventions utilizing instruments and assemblies thereof to stabilize and/or fixate a dysfunctional sacroiliac (SI) joint. The systems include a drill guide adapted to create a pilot SI joint opening in the dysfunctional SI joint through an incision comprising a length no greater than 3.0 cm; portions of the pilot SI joint opening being disposed in the sacrum and ilium bone structures. The drill guide includes a tri-mode fixation system adapted to position and stabilize the drill guide during creation of the pilot SI joint opening in the dysfunctional SI joint and delivery of the SI joint prosthesis therein. The systems also include a SI joint prosthesis configured to be inserted into the pilot SI joint opening of the dysfunctional SI joint, and a prosthesis deployment assembly configured to engage the SI joint prosthesis and advance the SI joint prosthesis into the dysfunctional SI joint.

Systems are described for conducting minimally invasive medical interventions utilizing instruments and assemblies thereof to stabilize and/or fixate a dysfunctional sacroiliac (SI) joint. The systems include a drill guide adapted to create a pilot SI joint opening in the dysfunctional SI joint through an incision comprising a length no greater than 3.0 cm; portions of the pilot SI joint opening being disposed in the sacrum and ilium bone structures. The drill guide includes a tri-mode fixation system adapted to position and stabilize the drill guide during creation of the pilot SI joint opening in the dysfunctional SI joint and delivery of the SI joint prosthesis therein. The systems also include a SI joint prosthesis configured to be inserted into the pilot SI joint opening of the dysfunctional SI joint, and a prosthesis deployment assembly configured to engage the SI joint prosthesis and advance the SI joint prosthesis into the dysfunctional SI joint.