A system includes ultrasound transducers configured to generate and direct ultrasound beams at a region within a portion of a subject's brain, sensors configured to measure a response from the portion of the subject's brain in response to one or more ultrasound beams, and an electronic controller in communication with the ultrasound transducers configured to generate, based on a measured response from the portion of the subject's brain in response to two or more ultrasound beams generated from two or more different angles, a model of the portion of the subject's brain, wherein the model has a higher resolution than a maximum resolution of a single ultrasound beam, and generate, based on the model of the portion of the subject's brain, stimulation parameters for the ultrasound transducers to generate and direct a stimulation ultrasound beam at the region within the portion of the subject's brain.

Disclosed herein are systems and methods for interactive graphical user interfaces (GUIs) that users (e.g., medical professionals) can use to interact with modelled versions of brains and easily and intuitively analyze deep and/or lateral structures in the brain. A user can, for example, selectively view structures and their connectivity data (e.g., nodes and edges) relative to other structures and connectivity data over a representation of a particular patient's brain. Emphasis can be minimized for certain foreground nodes and edges (e.g., lateral structures) to make it easier for the user to focus on and analyze deeper structures that otherwise can be challenging to visualize and understand. A method can include overlaying deep and non-deep nodes on a representation of a brain, displaying the representation of the brain in a GUI, receiving user input indicating interest in focusing on one or more deep nodes, and taking an action based on the input.

A method and apparatus used to prevent brain death by use of rapid and safe cooling of the brain is disclosed. The cisterna magna is accessed through a patient's neck and cooled artificial cerebrospinal fluid (aCSF) is circulated about spaces within the brain and in a subarachnoid space surrounding the brain by entering the cisterna magna with an entry through the neck of the patient with a specially designed needle/cannula which allows the flow of cooled aCSF about the brain. aCSF exits from an opening in the skull where a temperature/pressure sensor is placed. Data is sent to a computer-controlled motorized system that pumps cooled aCSF to the needle/cannula placed in the cisterna magna. The pumping of aCSF is controlled to maintain a predetermined temperature and/or pressure of the exiting aCSF.

According to various embodiments, there is provided a device including a processor configured to control a robotic system to autonomously position a transducer at a plurality of locations adjacent a subject's skull and to autonomously locate a window on the subject's skull within which an artery can be located, from which artery a signal can be returned to the transducer, the signal having an energy level exceeding a predefined threshold.

Arrangements described herein relate to systems, apparatuses, and methods for a disposable kit containing medical items configured for a medical device including a head cradle to support a head of a subject, the disposable kit includes a container that encloses a head cradle pad configured to be affixed to the head cradle, at least one fiducial marker configured to be disposed on a location at the head of the subject, and at least one enclosure configured to cover a portion of the medical device.

During acquisition of an ultrasound image feed, ultrasound control data frames are acquired that may be interspersed amongst the ultrasound data frames. The control data frames may use consistent reference scan parameters, irrespective of the scanner settings, and may not need to be converted to image frames. The control data frames can be passed to an artificial intelligence model, which predicts the suitable settings for scanning the anatomy that is being scanned. The artificial intelligence model can be trained with a dataset containing different classes of ultrasound control data frames for different settings, where substantially all the ultrasound control data frames in the dataset are consistently acquired using the reference scan parameters.

An illuminating ring assembly is disclosed. The illuminating ring configured to be used with a surgical access element. The illuminating ring assembly comprises a housing defined by a cover and a wall member extending from the cover, wherein the cover and wall member cooperate to define a cavity therein, a light element configured to be disposed with the cavity, and an attachment mechanism configured to selectively attach the housing to a surgical access element. Wherein the cover and the light element both include an opening therethrough.

A high-low intensity focused ultrasound treatment apparatus according to the present disclosure includes a plurality of ultrasound sources, and a controller to control a center frequency and intensity of focused ultrasound outputted from the ultrasound sources, wherein each of the ultrasound sources includes a first ultrasound transducer to output low-intensity focused ultrasound to detect a lesion, and a second ultrasound transducer to output high-intensity focused ultrasound to ablate or remove the detected lesion. The low-intensity focused ultrasound outputted from the first transducer may be used to detect a lesion in a patient's brain by applying a stimulus to the brain, and at the same time, investigating a response, and the high-intensity focused ultrasound outputted from the second transducer may be used to ablate or remove the detected lesion by applying a thermal or mechanical stimulus to the lesion.

A device is provided for diagnostic measurement by simultaneous multimodal analysis of a subject's head wherein the cerebral blood flow variations as well as the concentration level of oxygenation in the subject's blood are used to determine the presence and the pathophysiology of neurocognitive disorders, including the neurodegenerative disease referred to as Alzheimer's disease.

Arrangements described herein relate to systems, apparatuses, and methods for a headset system that includes a transducer configured to collect physiological data of a subject, a device housing configured to support the transducer, an insert portion disposed on the device housing, a support structure comprising a baseplate and a receiving portion, and a head cradle supported by the baseplate. The receiving portion extends in a direction that is oblique with respect to the baseplate. The insert portion is sized and shaped to engage the receiving portion to removably attach the device housing to the baseplate.