Methods, systems, and computer readable media for utilizing a therapeutic ultrasound device to perform mitral valve decalcification are disclosed. One method includes acquiring, via an ultrasound imaging component, imaging data of a mitral valve in real-time, defining a therapeutic region of interest corresponding to the mitral valve, and utilizing, by a system controller engine, imaging data from the ultrasound imaging component to determine an interval period of minimal mitral annular movement. The method further includes defining a sequence of therapeutic targets within the region of interest of the mitral valve, utilizing the imaging data acquired in real-time by the ultrasound imaging component to provide a therapeutic ultrasound transducer array with a location and depth of an intra-annular focal zone within the mitral valve, and emitting a high intensity focused ultrasound (HIFU) pulse wave from the therapeutic ultrasound transducer array to each of the therapeutic targets of the mitral valve during the determined interval period and in accordance with the defined sequence.

A medical system includes an ultrasound probe configured for insertion into an organ of a body, and a processor. The probe includes a two-dimensional (2D) ultrasound transducer array, and a sensor configured to output signals indicative of a position, direction and orientation of the 2D ultrasound transducer array inside the organ. The processor is configured to (a) using the signals output by the sensor, register multiple ultrasound images of a tissue region, acquired over a given time duration by the 2D ultrasound transducer array, with one another, (b) estimate, based on the ultrasound images acquired over the given time duration, three-dimensional displacements as a function of time for one or more locations in the tissue region, (c) estimate respective mechanical strains of the one or more locations in the tissue region, based on the three-dimensional displacements, and (d) present a time-dependent rendering of the mechanical strains to a user.

A medical system includes an ultrasound probe for insertion into an organ of a body and a processor. The ultrasound probe includes (i) a two-dimensional (2D) ultrasound transducer array, and (ii) a sensor configured to output signals indicative of a position, direction and orientation of the 2D ultrasound transducer array inside the organ. The processor is configured to (a) using the signals output by the sensor, register multiple ultrasound images of a tissue region, acquired over a given time duration by the 2D ultrasound transducer array, with one another, and (b) generate a map of the tissue region indicative of respective amounts of motion of tissue locations in the tissue region.

A medical system includes an ultrasound probe and a processor. The ultrasound probe is configured for insertion into an organ of a body and includes (i) a two-dimensional (2D) ultrasound transducer array, and (ii) a sensor configured to output signals indicative of a position and orientation of the 2D ultrasound transducer array inside the organ. The processor is configured to (a) using the signals output by the sensor, register multiple ultrasound image sections, acquired by the 2D ultrasound transducer array, with one another, (b) produce a union of the multiple registered ultrasound image sections, to form a rendering of at least a portion of the organ, and (c) present the rendering to a user.

A transducer device may include an active layer having a proximal surface and a backing layer having a distal side and a proximal side, the distal side being adjacent to the proximal surface. The proximal side may include (1) at least one first reflective surface approximately parallel to the proximal surface and positioned a first distance from the proximal surface, and (2) at least one second reflective surface approximately parallel to the proximal surface and positioned a second distance from the proximal surface, the second distance being different than the first distance.

A handle apparatus comprising detachable hardware and void regions or attachment devices that accommodate the shape of surgical devices and imaging units such that the device is held securely and mechanically fixed to the imaging unit within the handle assembly.

A method of constructing a replacement valve for repairing a heart having an annulus separating upstream and downstream regions. The method includes obtaining a representative perimetrical length of the annulus and fabricating a frame having a hub and legs extending outward from the hub to anchors axially offset from the hub. The method includes fabricating an annular band having a circumferential length corresponding to the representative length and attaching the band to the legs. The method includes forming a flexible component having a convex face having a margin and an axially offset region. And a concave face and connecting the offset region to the hub and portions of the margin to the band and/or a portion of the frame. The valve component moves to an open position when upstream pressure is greater than downstream pressure and to a closed position when downstream pressure is greater than upstream pressure.

An ultrasonic detection method and ultrasonic imaging system for a fetal heart. Since after three-dimensional volume data is obtained, at least one point within a fetal heart in the three-dimensional volume data is identified, the spatial position where a fetal heart cross-section is located in the three-dimensional volume data is identified according to the point, and the fetal heart cross-section is then extracted from the three-dimensional volume data according to the identified spatial position, the fetal heart cross-section can be quickly acquired from the three-dimensional volume data. The present invention is simple and easy to use, and is convenient for a doctor to make a diagnosis.

For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. The machine-learnt multi-task generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. The machine-learnt multi-task generator is trained to output both the 3D segmentation and a complete volume. The 3D segmentation may be used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.

Aspects of the technology described herein related to monitoring fetal heartbeat and uterine contraction signals. An ultrasound system may be configured to sweep a volume to collect ultrasound data, detect a fetal heartbeat and/or uterine contraction signal in the ultrasound data, and automatically steer an ultrasound beam to monitor the fetal heartbeat and/or uterine contraction signal. The ultrasound system may be further configured to determine a location where the fetal heartbeat and/or uterine contraction signal is detectable or detectable at a highest quality. The ultrasound system may include a wearable ultrasound device, such as an ultrasound patch coupled to a subject. The wearable ultrasound device may have a two-dimensional array of ultrasonic transducers capable of steering ultrasound beams in three dimensions.