The present disclosure relates to methods for predicting time-to-delivery in pregnant women. The methods include predicting that a pregnant woman will deliver within a predetermined time frame if PAMG-1 is determined to be present at a level above a predetermined detection threshold in a vaginal fluid sample obtained from the pregnant woman. Also provided are methods for determining a patient's risk of preterm labor and/or spontaneous rupture of the chorioamniotic membrane.

A sexual assault evidence collection kit that may be used by the victim or other non-professionals. The kit may be simplified compared to kits for professional use, and may be usable with no specialized training. Victims may therefore be able to collect evidence themselves after an assault, instead of searching for a facility with personnel trained in forensic evidence collection, and enduring a long, intrusive examination. Embodiments may include a package (for example a clear bag) and the following components inside the package: gloves, swabs, swab containers, water, evidence collection bags, evidence bag sealing tape, evidence collection tape, a permanent marker, and instructions on how to identify, collect, seal, document, and store evidence.

Efficient harvesting of cells, cell fragments, free nuclei, and DNA material from female reproductive system is made possible by processing gelatinous part of cervical mucus. Rinsing may be used to separate the gelatinous part of cervical mucus from the remainder of the cervical mucus sample.

A urine specimen collection apparatus configured to collect a urine specimen from a human user or from an animal is described. The apparatus includes a planar component affixed between a handle portion and a collection portion. The collection portion comprises an outer periphery and an inner periphery, where the inner periphery is defined by an opening. The opening extends through a width of the collection portion and is configured to receive a urine specimen container therein. The handle portion is configured to be gripped by a user during use.

Disclosed herein a female hygienic device for diagnosing and/or monitoring cancer, comprising at least one absorption zone for accumulating vaginal discharge; and at least one indication zone comprising at least one agent for visually reacting with a physiological marker, the physiologic marker is indicative of a cancerous condition.

A personal hygiene device may have a main body with an absorbent material configured to absorb a fluid, a sensor disposed within the main body, and a controller configured to communicate with the sensor. The sensor has a conductor and an insulator containing at least a portion of the conductor, and the sensor is configured to detect a first electrical value and a second electrical value that is different from the first electrical value. The sensor is also configured to transmit a signal to the controller upon detection of the second electrical value.

Provided herein are methods for detecting a menstrual cycle disorder. Menstrual cycle disorders is detected through analysis of a property of a collected menstrual fluid sample, such as gene expression, flow rate, protein content, nucleic acid content, biomarkers, or other properties.

A universal single-handed device for self-collection of a biological sample is described herein. The single-handed device may comprise a sheath comprising a distal end for insertion into a portion of a user's body, a shaft at least partially within the sheath, having a collection head for collecting the biological sample positioned at the distal end thereof, and an actuator coupled to the shaft to transition the distal end between an open configuration and a closed configuration. The collection head is covered by the distal end in the closed configuration and is exposed when the distal end is in the open configuration.

A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification.

The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.