The present disclosure provides a female reproductive system sample collector, including a sampling device and an elution preservation device, where the elution preservation device is filled with an elution preservation solution, after sampling is completed, the sampling device is submerged in the elution preservation solution of the elution preservation device and sealed for preservation; the sampling device includes a sampling rod and a sheath; the sampling rod includes an operating rod, a straight rod brush and a ball head brush, an opening and closing cover corresponding to the ball head is disposed at a front end of the sheath, and the opening and closing cover includes four oscillating rods that are hinged with a front port of the sheath and the oscillating rods are connected through thin films. The present disclosure can collect cells or nucleic acids of uterus and ovaries in a uterine cavity, a sampling rod can deform in a shape along an outline of the uterine cavity. The sampling rod can avoid sample falling when finishing sampling and recovering; an elution preservation device can prevent liquid from overflowing and leaking or polluting a sealing cap. The present disclosure provides a quick, convenient, widely applicable and less discomfort sample collection channel and a sample protection method for early detection of the ovarian cancer, the endometrial cancer and the cervical cancer.

The current invention concerns a sample vial for receiving a liquid cell sample, to be used in conjunction with a digital holographic microscope (DHM), said sample vial comprises at least two compartments in fluid connection with one another, said compartments comprising at least one pair of screening surfaces, said screening surfaces are essentially flat; and characterized in that the distance between the pair of screening surfaces of the second compartment is smaller than the distance between the pair of screening surfaces of the first compartment. In a second and third aspect, the current invention pertains to a method and system for analyzing a liquid cell sample by DHM, employing the sample vial of the current invention.

The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same.

The present invention includes a method of obtaining a biological sample from the nose, nasal cavities, nasal pharynx, oral mucosa, or saliva of a subject to be used for detection of a virus (e.g., a SARS-Co V-2 virus), and kits for performing the method.

The collection kit 1 according to the present invention comprises a collection tool 10 for collecting saliva, a container body for housing the collection tool 10 and a preservation solution for saliva, and a cap for closing the container body. The collection tool 10 comprises a saliva absorbent 12 for collecting saliva, a housing body 14 for housing the saliva absorbent 12, and a pressing body 16 for pressing a collection body 12 and forming a suction space S that is for sucking the saliva and the preservation solution from the outside of the container body 22.

A method for treating tissue through a branched luminal network of a patient is provided. A pathway to a point of interest in branched luminal network of a patient is generated. An extended working channel is advanced transorally into the branched luminal network and along the pathway to the point of interest. The extended working channel may be positioned in a substantially fixed orientation at the point interest. A tool is advanced though the extended working channel to the point of interest. Tissue at the point of interest is treated.

A protective guide for protecting a cell extraction device used during a Pap smear. An access tunnel receives the cell extraction device and allows for access and movement of the cell extraction device. A protective chamber covers and protects the head of the cell extraction device as the cell extraction device is being removed and inserted from the patient's vagina. A protective guide connector attaches the protective guide to an imaging transducer. After inserted into the patient's vagina, the location of the patient's cervix is determined by utilization of the imaging transducer. Once the cervix is located the cell extraction device is pushed outward from the protective chamber so that the cell extraction device head contacts the cervix and then removes cells from the cervix. The cell extraction device head is then pulled back into the protective chamber and the protective guide is removed from the patient's vagina.

Provided herein are kits, devices and methods for rapid analysis of biological samples. In particular, kits, devices and methods described herein can be applied to rapid nucleic acid analysis of solid tissue samples.

Described is a swab comprising a rod having a longitudinal axis and a tip. The tip includes a proximal region at a distal end of the rod, a distal region opposite the proximal region, and a plurality of straight blades extending from the proximal region to the distal region, parallel to the longitudinal axis.

A swab for taking biological samples which has a support rod having an end portion coated with a layer of fibres is provided. Each of the fibres extends in length orthogonally to a surface of the support rod with a respective free end portion. The layer of fibres has hydrophilic properties to allow absorption of biological samples. Each of the fibres is mechanically anchored at a bottom portion thereof to a textile substrate fixed to a surface of the end portion of the support rod.