Devices and methods for sealing staples in tissue using a plurality of adjunct segments are described herein. In one embodiment, an end effector for a surgical instrument is described that can include first and second jaws, where the first jaw has a cartridge body removably attached thereto and the cartridge body has a plurality of staple cavities configured to seat staples therein. The second jaw can have an anvil with a plurality of staple forming openings formed therein, and at least one of the first and second jaws can be movable relative to the other jaw. The end effector can also include a plurality of sealing adjunct segments coupled to one another and at least one of the first and second jaws such that a staple ejected from the cartridge body passes through one of the plurality of sealing adjunct segments and tissue disposed between the first and second jaws.

The present disclosure provides a system for injecting a drug eluting construct in a patient. The construct includes multiple cellular based microcaspules, wherein the multiple cellular based microcapsules create at least one of a plurality of layers or sections of microcapsules joined together to comprise an implant. There is a medicinal agent within the microcapsules. A syringe and needle inject the implant constructed of microcapsules into the patient at least one of during and after a surgical procedure. The medicinal agent controllably releases into the patient both immediately and at a delayed time.

The present disclosure relates generally to apparatus, devices, and methods for increasing force distribution at a suture-tissue interface. In some embodiments, a tissue suturing device may include a deployment device and a plurality of tissue supports deployable from the deployment device towards a target tissue. The plurality of tissue supports may each include a central opening for receiving a suture during deployment.

The present disclosure provides medical products and methods including an applicator tip for connection to a syringe. The applicator tip is advantageous when dispensing viscous fluids, such as adhesives and/or sealants.

The present disclosure provides a method of positioning an implant in a patient. The method includes inserting a deflated biodegradable balloon into a joint of the patient, wherein the biodegradable balloon is wedged between at least one of bone and soft tissue in the joint of the patient. The biodegradable balloon is inflated by injecting a warmed sterile liquid from a syringe through an inlet valve and the inflated biodegradable balloon is at least one of sized and shaped to fit within the surgical field. The expanded biodegradable balloon is a joint spacer, changing the spatial relationship between the bones and soft tissue in the joint of the patient.

Devices and methods for applying sealants to surgical instruments. In one embodiment, a surgical device is described that can include at least one nozzle formed at a proximal end of the device that is configured to receive a sealant, as well as an applicator formed at a distal end of the device that is configured to deliver the sealant received by the at least one nozzle. The applicator can be configured to interface with at least one of a first and second jaw of a surgical stapler such that the sealant delivered from the applicator can be deposited into a plurality of openings formed in the surgical stapler.

Devices and methods for forming an anastomosis between two body lumens are described herein. In one embodiment, an anastomosis can be formed by transecting a body lumen using a linear surgical stapler that delivers a plurality of sealing adjuncts in combination with a plurality of surgical staples along a staple line, where the plurality of sealing adjuncts are coupled to one another by a suture. A circular surgical stapler can be used to create an anastomosis with a second body lumen across the staple line. Before actuating the circular stapler, the proximal and distal ends of the staple line can be drawn into a central lumen of the circular stapler using the suture extending between the plurality of sealing adjuncts such that the staple line is resected when the circular stapler is actuated.

The present disclosure provides a system for injecting a drug eluting construct in a patient. The construct includes multiple cellular based microcaspules, wherein the multiple cellular based microcapsules create at least one of a plurality of layers or sections of microcapsules joined together to comprise an implant. There is a medicinal agent within the microcapsules. A syringe and needle inject the implant constructed of microcapsules into the patient at least one of during and after a surgical procedure. The medicinal agent controllably releases into the patient both immediately and at a delayed time.

The present disclosure provides a method of positioning a medical device in a patient. The method includes coating a balloon with a substance, wherein the coating substance comprises at least one layer comprised at least partially of a medicinal agent and a polymer, inserting the deflated balloon into a cardiac system of the patient, placing the balloon in the proper location in the cardiac system of the patient, and inflating the balloon by injecting a sterile liquid from a syringe into the balloon. The method also includes positioning the substance proximate the tissue of the cardiac system of the patient, wherein the cardiovascular drug medicinal agent comprising the substance is drug eluting.

Apparatus and methods are described, including apparatus for treating a cavity in a human body, the apparatus including a delivery tube. A bather device has a collapsed configuration and an expanded configuration, the barrier device moving from the collapsed configuration to the expanded configuration upon being deployed from the delivery tube. A pushing element, slidably disposed within a lumen of the delivery tube, is configured to deploy the barrier device from the delivery tube by pushing the bather device. One or more bather-deployment elements are coupled to the barrier device and to the pushing element, the bather-deployment elements being configured to conformingly contact the barrier device with tissue surrounding the cavity. Other applications are also described.