A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

A medical dispensing device which includes a catheter, an applicator tip at a distal end of the catheter, the catheter and the applicator tip defining a lumen having a longitudinal axis and a distal opening, a plunger in the lumen and movable along the longitudinal axis, and a plurality of elements in the lumen proximal to the distal opening and distal to the plunger, the plurality of elements stacked along the longitudinal axis for dispersement of one element at a time through the distal opening via a force applied by the plunger.

A laparoscopic stapler for stapling tissue is proved. The laparoscopic stapler comprises a flippable anvil assembly and a flippable staple housing assembly which can be moved with respect to the flippable anvil assembly, wherein the anvil assembly and the staple housing assembly are respectively configured to be operable in a first configuration and a second configuration, wherein in the first configuration, the anvil assembly and the staple housing assembly both have a low profile so that the anvil assembly and the staple housing assembly can be delivered separately through a 12 mm trocar, and in the second configuration, the anvil assembly and the staple housing assembly has a high profile for performing tissue stapling.

Several embodiments are set forth of devices, systems and methods for modifying an atrial appendage such as a left atrial appendage (LAA). In one embodiment, a medical device includes a frame member and a tissue growth member. The frame member includes a unitary, seamless central portion having a plurality of struts defining a multi-cellular structure and an anchoring system, the plurality of struts extending between and configured to self-expand and directly bias the anchor system to anchor the frame member at least partially within the LAA. With this arrangement, the tissue growth member is attached to the frame member to occlude the LAA.

Devices and methods for occluding the left atrial appendage (LAA) to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. A foam implant encapsulated with a tough thromboresistent membrane is placed via transvascular means into the LAA and anchored with adhesives and/or mechanical anchors. Tissue over- and in-growth are optimized to anchor the implant in place and provide a permanent occlusion.

An applicator is provided for a flowable media, particularly an adhesive contained in a container and the applicator includes an elongate body member having an internal cavity that holds the container. The cavity has a distal end with a breaking means that is actuated by an axial force. Various embodiments of the actuator are shown to apply the force, including a wire cracker and a molded integral handle member with a lever linkage that bears against a ram which holds the ampoule and having a spring arm that rides within the cavity to oppose a pivoting force on the handle. These embodiments also enable single handed use.

Disclosed are devices and methods suitable for application of a curable fluid composition to a bodily organ, such as to a lower portion of a bodily organ. The device comprises a monolithic piece of material having a lower surface, two spaced-apart sides, and two spaced-apart walls connecting the two spaced-apart sides. A receptacle for containing the curable fluid composition is defined by the lower surface, the two sides, and the two walls. At least a portion of the height of the two walls is less than the height of at least a portion of the two sides. The device is deployable underneath the bodily organ such that a lower portion of the bodily organ is supported by at least a portion of each of the two walls.

An occlusion device with particular utility in occlusion of left atrial appendages is described. The occlusion device embodiments utilize an inflatable balloon or expandable element used to occlude the treatment site.

A device for applying a tissue healing agent includes an insertion member extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, a delivery element including a first surface and a second surface opposing one another, the delivery element movable between a closed configuration, in which the delivery element is compressed to be received within the channel, and an open configuration, in which the delivery element is substantially planar, and a first tissue healing agent formed in a sheet configuration and disposed on the first surface of the delivery element.

A method of performing bariatric surgery using a robotic surgical system includes positioning a gastrectomy device in a selected location in a stomach; applying an adherent material to the stomach along a desired transection line; and cutting the stomach along the desired transection line delineated by the adherent material.