Disclosed is a delivery device, kit, system, method, etc. for localized fusion of leaflets of a tissue valve, for example, a native heart valve, using an adhesive. The delivery device can have one or more capture features for capturing separate leaflets, for example, the anterior and posterior mitral leaflets. An applicator can be configured to apply a biocompatible adhesive between the captured leaflets, and one or more curing elements can be configured to cure the applied biocompatible adhesive. The kit can have the aforementioned delivery device, and the biocompatible adhesive used therewith. The method can include positioning the aforementioned delivery device adjacent the anterior and posterior mitral leaflets, capturing the mitral leaflets between the paddles of the delivery device, applying a biocompatible adhesive between the captured mitral leaflets via the applicator, and curing the applied biocompatible adhesive via the energy elements to locally fuse the mitral leaflets.

A thin, flexible patch for decompressing a hollow structure, such as an ovarian cyst is applied to the hollow structure during a surgical procedure. The patch is adhered to the structure by an adhesive layer to form a fluid-tight seal with the structure. During the surgical procedure, such as a laparoscopic procedure, an aspiration needle is inserted through the patch and into the hollow structure with the patch forming a fluid-tight seal around the needle. Fluid is withdrawn by the aspiration needle, causing the structure to decompress and to be reduced in size. Once the structure is reduced in size it can be removed, for example, through a minimally invasive surgical port. The patch includes handles that facilitate grasping and manipulating the structure using laparoscopic instruments. The patch may also be formed by applying a curable material to the hollow structure and curing the material in situ so that it forms a patch that is adhered to the structure.

The present invention relates to an aqueous composition comprising an aqueous solution, -TCP, a silicate compound and a phosphorylated amino acid. The composition has improved mechanical strength and is easily applied and may be used as a tissue adhesive, implant or a filler.

A surgical instrument is provided including a handle portion and a body portion extending distally from the handle portion and defining a longitudinal axis. The surgical instrument also includes a grasper disposed at a distal end of the body portion, the grasper including an ultraviolet (UV) light mechanism for performing UV tacking of an implant. The implant is positioned between the first and second jaw members of the grasper: (i) to be placed at a surgical site and (ii) to be exposed by a UV light emitted from the UV light mechanism such that the UV tacking of the implant to the surgical site is performed.

An intracranial stent includes a proximal end, a distal end, and a tubular sidewall extending there between and a patch covering at least a portion of the sidewall; wherein the patch is capable of diverting blood flow past the neck of an intracranial aneurysm. The patch may be made of a photon-activatable material or a tightly woven metal material with a density greater than a density of the sidewall itself.

A composition for the adhesion of biological tissues to one another, for the adhesion of a material to a biological tissue, for the adhesion of an adhesive or of a substance to the surface of a biological tissue, for blocking an orifice in a biological tissue, for reinforcing a biological tissue and/or for fixing and stabilising a biological tissue, characterized in that it comprises a monomer that is polymerisable under the effect of ultraviolet (UV) or near visible radiation and in that the viscosity of said composition is less than 40 mPa.Math.s at 20 C.

The present invention relates to an aqueous composition comprising an aqueous solution, a-TCP, a silicate compound and a phosphorylated amino acid. The composition has improved mechanical strength and is easily applied and may be used as a tissue adhesive, implant or a filler.

Medical systems, devices, and related methods for delivery of treatment agent(s) are described. The medical device includes a container. The container includes a chamber and a distal cap. The distal cap of the container includes one or more holes therethrough. The chamber includes a balloon or a pouch, and a fluid cavity. The balloon or pouch radially surrounds the fluid cavity. Transitioning the balloon or pouch from a deflated configuration to an inflated configuration or from the inflated configuration to the deflated configuration urges a fluid within the fluid cavity through one or more holes of the distal cap.

The invention primarily relates to fastening and stabilizing tissues, implants, and/or bondable materials, such as the fastening of a tissue and/or implant to a bondable material, the fastening of an implant to tissue, and/or the fastening of an implant to another implant. This may involve using an energy source to bond and/or mechanically to stabilize a tissue, an implant, a bondable material, and/or other biocompatible material. The invention may also relate to the use of an energy source to remove and/or install an implant and/or bondable material or to facilitate solidification and/or polymerization of bondable material.

Disclosed is a delivery device, kit, system, method, etc. for localized fusion of leaflets of a tissue valve, for example, a native heart valve, using an adhesive. The delivery device can have one or more capture features for capturing separate leaflets, for example, the anterior and posterior mitral leaflets. An applicator can be configured to apply a biocompatible adhesive between the captured leaflets, and one or more curing elements can be configured to cure the applied biocompatible adhesive. The kit can have the aforementioned delivery device, and the biocompatible adhesive used therewith. The method can include positioning the aforementioned delivery device adjacent the anterior and posterior mitral leaflets, capturing the mitral leaflets between the paddles of the delivery device, applying a biocompatible adhesive between the captured mitral leaflets via the applicator, and curing the applied biocompatible adhesive via the energy elements to locally fuse the mitral leaflets.