Patent classifications
C12Q1/6827
Gene controlling fruit color phenotype in palm
- Rajinder Singh ,
- Leslie Ooi Cheng Li ,
- Leslie Low Eng Ti ,
- Rahimah Abdul Rahman ,
- Meilina Ong Abdullah ,
- Jayanthi Nagappan ,
- Rozana Rosli ,
- Mohd Amin Ab Halim ,
- Rajanaidu Nookiah ,
- Chan Kuang Lim ,
- Norazah Azizi ,
- Ravigadevi Sambanthamurthi ,
- Rob Martienssen ,
- Steven W. Smith ,
- Nathan D. Lakey ,
- Andrew Van Brunt ,
- Jared Ordway ,
- Michael Hogan ,
- Chunyan Wang
Methods, compositions, and kits for predicting and controlling fruit color in palm.
Application of epigenetic chromosomal interactions in cancer diagnostics
The invention provides a method of determining the epigenetic chromosome interactions which are relevant to a prognostic companion epigenetic test for cancer.
Application of epigenetic chromosomal interactions in cancer diagnostics
The invention provides a method of determining the epigenetic chromosome interactions which are relevant to a prognostic companion epigenetic test for cancer.
Application of epigenetic chromosomal interactions in cancer diagnostics
The invention provides a method of determining the epigenetic chromosome interactions which are relevant to a prognostic companion epigenetic test for cancer.
Detection of nucleotide variation on target nucleic acid sequence
The present invention relates to the detection of a nucleotide variation on a target nucleic acid sequence using an amplification blocker and a VD-PTOCE (Variation Detection by PTO Cleavage and Extension) assay. The present invention is significantly effective in the detection of a minority mutation in an excess of wild-type DNA.
Detection of nucleotide variation on target nucleic acid sequence
The present invention relates to the detection of a nucleotide variation on a target nucleic acid sequence using an amplification blocker and a VD-PTOCE (Variation Detection by PTO Cleavage and Extension) assay. The present invention is significantly effective in the detection of a minority mutation in an excess of wild-type DNA.
Detection of nucleotide variation on target nucleic acid sequence
The present invention relates to the detection of a nucleotide variation on a target nucleic acid sequence using an amplification blocker and a VD-PTOCE (Variation Detection by PTO Cleavage and Extension) assay. The present invention is significantly effective in the detection of a minority mutation in an excess of wild-type DNA.
Compositions and methods of treating and reducing risk of conditions associated with elevated 4-ethylphenyl sulfate in canines and identifying canines at risk of such conditions
Methods of identifying canine subjects having an increased likelihood of developing elevated levels of 4-ethylphenyl sulfate, canine stress, canine anxiety and/or an inhibition of growth of beneficial microbes and promotion of growth of harmful microbes are disclosed. Methods comprise analyzing a biological sample obtained from the canine subject for the presence of two copies of a minor allele of the single nucleotide polymorphism BICF2P1175095 in a canine subject. Methods of treating the identified canine subjects by administering an effective amount of tomato pomace are also disclosed. Methods of treating canine subjects for elevated 4-EPS levels, canine anxiety or canine stress are disclosed. Canine food compositions that comprises tomato pomace are disclosed.
Compositions and methods of treating and reducing risk of conditions associated with elevated 4-ethylphenyl sulfate in canines and identifying canines at risk of such conditions
Methods of identifying canine subjects having an increased likelihood of developing elevated levels of 4-ethylphenyl sulfate, canine stress, canine anxiety and/or an inhibition of growth of beneficial microbes and promotion of growth of harmful microbes are disclosed. Methods comprise analyzing a biological sample obtained from the canine subject for the presence of two copies of a minor allele of the single nucleotide polymorphism BICF2P1175095 in a canine subject. Methods of treating the identified canine subjects by administering an effective amount of tomato pomace are also disclosed. Methods of treating canine subjects for elevated 4-EPS levels, canine anxiety or canine stress are disclosed. Canine food compositions that comprises tomato pomace are disclosed.
Method for detecting gene mutation
An object of the present invention is to provide a novel method for designing a primer ensuring reactivity and discriminatory power in a method for detecting a single base substitution based on an ASP-PCR method and to provide a method for easily detecting multiple point mutations within overlapping amplicons, particularly, two adjacent single base substitutions. The single base substitutions can easily be detected by using a mutant primer in which the base of the third nucleotide from the 3′ end corresponds to the base of a mutant nucleotide of a single base substitution contained in a nucleic acid sample, in which the base of the second nucleotide from the 3′ end is not complementary to the base of the corresponding nucleotide of the nucleic acid, and in which the bases of the other nucleotides are complementary to the bases of the corresponding nucleotides of the nucleic acid.