A non-toxic vehicle for hormone therapy. The non-toxic vehicle includes a cationic lipid or a neutral lipid and polyethylene glycol.

A hormone modulator for causing cellular apoptosis in triple-negative breast cancer cells. The hormone modulator includes at least one of 5-androsten-3,17-diol and 5-androsten-3,7,17-triol and estradiol.

A method of modulating an immune response. The method includes administering a treatment comprising delta 5-androsten-3B, 17B-diol, delta 5-androsten-3B, 7B, 17B-triol, or both.

A method of preparing a wound model. The method includes simulating a non-healing wound edge, simulating eschar, simulating a fibrin layer, simulating biofilm, and simulating foreign debris.

A device includes an annular, elastic band having a rectangular cross section. A foil band is affixed to a surface of the elastic band. A contiguous fabric sheath is configured to encase the elastic band and foil band.

A training simulator for intraoperative neuromonitoring (IONM) systems includes channels where at least one of the channels is identified as an active stimulation channel and a subset of the rest of the channels is identified as reference or pick up sites. Channels of the subset having signal data that exceed a predefined threshold are retained for further processing, while channels with signal data that do not exceed the threshold are eliminated from further reporting. Response data for the remaining channels are generated in advance of a future time when the response would occur. The generated data is time stamped and stored for display at a time window when requested by the system.

Embodiments of the present invention provide markers, phantoms, and associated methods of calibration which are suitable for use in both magnetic resonance imaging and radiographic imaging systems. A marker includes a first marker component having a first hydrogen proton density and a first mass density; and a second marker component having a second hydrogen proton density different than the first hydrogen proton density, and a second mass density different than the first mass density. The first marker component and the second marker component are non-magnetic.

A phantom to determine navigational error in a surgical navigation system that tracks the location of an elongate tool having a tip and a shaft based on a plurality of fiducials attached to the elongate tool. The phantom includes a base portion that models a lower portion of a mammalian head and having a top surface with a plurality of touch points, each of the touch points being a respective indentation, and a frame detachably securable to the base portion and having an upper portion spaced apart from the top surface, the upper portion having defined therein a plurality of apertures. A tip of the elongate tool is to be inserted through said one of the apertures and in one of the touch points, and the surgical navigation system determines positional and angular error.

An apparatus for evaluating performance of an ultrasonic transducer includes a transducer assembly having an ultrasonic transducer and an acoustic medium and configured to transmit and receive an ultrasonic wave, a storage unit configured to store a reference signal value which represents the performance of the ultrasonic transducer, and a processing unit configured to control the transducer assembly to emit ultrasonic wave and receive a response (echo) signal thereto to measure a magnitude or energy amount of the response signal, the processing unit comparing a measured value with the reference signal value stored in the storage unit to evaluate the performance of the ultrasonic transducer.

A simulation device and method for using same are provided for simulating a position of a replica human spine due to different pathologies and different surgical positions. The simulation device includes a carrier portion rotatably attached to a base portion. The carrier portion supports a first adjuster, a second adjuster, and a third adjuster for supporting various portions of the replica human spine. The carrier portion and the first, second, third supports affording adjustment of the position of the replica human spine.