Patent classifications
C12Q1/6865
OLIGONUCLEOTIDES FOR USE IN DETERMINING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE
Methods for use in multiplex amplification and or detection of Trichomonas vaginalis. The multiphase amplification provides fast, quantitative, sensitive detection with lower variability at low analyte concentrations. Described are detection probes, capture probes, amplification oligonucleotides, nucleic acid compositions, probe mixes, methods, and kits useful for amplifying and determining the presence of Trichomonas vaginalis in a test sample.
OLIGONUCLEOTIDES FOR USE IN DETERMINING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE
Methods for use in multiplex amplification and or detection of Trichomonas vaginalis. The multiphase amplification provides fast, quantitative, sensitive detection with lower variability at low analyte concentrations. Described are detection probes, capture probes, amplification oligonucleotides, nucleic acid compositions, probe mixes, methods, and kits useful for amplifying and determining the presence of Trichomonas vaginalis in a test sample.
OLIGONUCLEOTIDES FOR USE IN DETERMINING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE
Methods for use in multiplex amplification and or detection of Trichomonas vaginalis. The multiphase amplification provides fast, quantitative, sensitive detection with lower variability at low analyte concentrations. Described are detection probes, capture probes, amplification oligonucleotides, nucleic acid compositions, probe mixes, methods, and kits useful for amplifying and determining the presence of Trichomonas vaginalis in a test sample.
Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors
The present application provides imidazolyl pyrimidinylamine inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.
MULTIPHASE NUCLEIC ACID AMPLIFICATION
Improved methods for use in nucleic acid amplification, including multiplex amplification, where the amplification is carried out in two or more distinct phases are disclosed. The first phase amplification reaction preferably lacks one or more components required for exponential amplification. The lacking component is subsequently provided in a second, third or further phase(s) of amplification, resulting in a rapid exponential amplification reaction. The multiphase protocol results in faster and more sensitive detection and lower variability at low analyte concentrations. Compositions for carrying out the claimed methods are also disclosed.
MULTIPHASE NUCLEIC ACID AMPLIFICATION
Improved methods for use in nucleic acid amplification, including multiplex amplification, where the amplification is carried out in two or more distinct phases are disclosed. The first phase amplification reaction preferably lacks one or more components required for exponential amplification. The lacking component is subsequently provided in a second, third or further phase(s) of amplification, resulting in a rapid exponential amplification reaction. The multiphase protocol results in faster and more sensitive detection and lower variability at low analyte concentrations. Compositions for carrying out the claimed methods are also disclosed.
MULTIPHASE NUCLEIC ACID AMPLIFICATION
Improved methods for use in nucleic acid amplification, including multiplex amplification, where the amplification is carried out in two or more distinct phases are disclosed. The first phase amplification reaction preferably lacks one or more components required for exponential amplification. The lacking component is subsequently provided in a second, third or further phase(s) of amplification, resulting in a rapid exponential amplification reaction. The multiphase protocol results in faster and more sensitive detection and lower variability at low analyte concentrations. Compositions for carrying out the claimed methods are also disclosed.
Disease resistant plant methods and compositions
The present invention provides methods and compositions for producing elite lines of corn exhibiting anthracnose stalk rot (ASR) resistance. Also provided in the present invention are corn plants exhibiting ASR resistance resulting from such methods, and methods for breeding corn such that the ASR resistance traits may be transferred to a desired genetic background.
Disease resistant plant methods and compositions
The present invention provides methods and compositions for producing elite lines of corn exhibiting anthracnose stalk rot (ASR) resistance. Also provided in the present invention are corn plants exhibiting ASR resistance resulting from such methods, and methods for breeding corn such that the ASR resistance traits may be transferred to a desired genetic background.
Automated cell processing methods, modules, instruments, and systems
In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.