A method of stapling tissue is disclosed. The method can include obtaining a staple cartridge including a plurality of staples, wherein each staple has a base and a leg extending from the base. The stapling method can also include firing the staples from the staple cartridge, wherein the staples are fired into tissue in a staple line. The staple line can include a first portion having a first flexibility and a second portion having a second flexibility, wherein the second flexibility is different than the first flexibility. A method of stapling tissue can also include adapting an anvil with an anvil plate having an arrangement of staple-forming pockets that differs from the staple-forming pockets in the anvil.

A system for implant delivery includes an implant and an inserter. The implant includes a body that extends between first and second ends. The implant includes retainers extending outwardly from the first and second ends. The retainers are received in corresponding jaws of the inserter. When the implant is connected to the inserter and the inserter is actuated, the implant elastically deforms.

A tissue displacing and fastening device is provided for manipulating and fastening tissue together. The device includes a tissue displacing elements, which displaces tissue. A fold is formed from the displaced tissue and the tissue is fastened together to secure the fold.

A surgical stapler includes a tubular body portion and a cartridge assembly disposed at a distal end of the body portion for expelling an annular array of staples. Each of the staples of the annular array of staples has a generally bent backspan. An anvil member disposed at the distal end of the tubular body portion is positioned opposite the cartridge assembly to clinch the staples in tissue upon expulsion of the staples from the cartridge assembly. The anvil member has a corresponding annular array of staple forming buckets. Each of the buckets is configured to accommodate the generally bent configuration of the staples to facilitate formation thereof.

The present disclosure includes a plurality of securing devices. For example, the present disclosure includes securing devices comprising sutures, everting anchors, and inverting anchors. The sutures and anchors disclosed herein may be capable of deployment to a depth within a body lumen, such that body tissue external to the body lumen is not damaged by the devices. Moreover, in various embodiments, the securing devices described herein may couple one or more medical devices (e.g., stents, grafts, and/or stent-grafts) to body tissue such as a body lumen.

A surgical instrument comprising a housing, an elongate shaft defining a longitudinal axis, an end effector, a firing member, and a laminate firing actuator connected to the firing member is disclosed. The elongate shaft comprises an articulation joint defining an articulation axis that is transverse to the longitudinal axis, a first lateral buckling support positioned on a first side of the articulation joint, and a second lateral buckling support positioned on a second side of the articulation joint. The laminate firing actuator extends through the articulation joint. The laminate firing actuator extends intermediate the first lateral buckling support and the second lateral buckling support. The first lateral buckling support and the second lateral buckling support engage the laminate firing actuator when the end effector is articulated about the articulation joint.

Disclosed is an endoscopic stapler that can be operated through the small working channel of a laryngoscope, other rigid endoscope, or a natural orifice to safely and effectively connect tissues permanently or semi-permanently. The endoscopic stapler apparatus includes a handle including a trigger, an outer shaft coupled to the handle, and an inner shaft with prongs positioned at a distal end of the inner shaft. The endoscopic stapler further includes a hook, wherein the hook and prongs are positioned to capture a staple at a tip of the prongs, wherein a proximal end of the inner shaft is coupled to the trigger, and wherein activation of the trigger causes the prongs to translate away from the handle causing the prongs to bend and close the staple.

In various embodiments, a tissue thickness compensator can comprise one or more capsules and/or pockets comprising at least one medicament therein. In at least one embodiment, staples can be fired through the tissue thickness compensator to rupture the capsules. In certain embodiments, a firing member, or knife, can be advanced through the tissue thickness compensator to rupture the capsules.

An introducer sheath is described. The introducer sheath may include a tubular body. The tubular body may extend from a distal end toward a proximal end. The tubular body may include a lumen. The lumen may at least partially be defined by a wall. A channel may be disposed within the wall. The channel may be configured to receive a guidewire. The tubular body may include an expandable portion expandable to increase a cross-sectional area of the lumen.

Devices and methods of endolumenal formation of gastric sleeves are described. Some embodiments allow templating of a gastric sleeve by a gastric bougie, exposing a selected amount of tissue for suturing access, while maintaining sufficient internal working space for suturing within the template lumen.