A tissue approximation device for wound closure having a first arm having a proximal end and a distal end, a second arm having a proximal end and a distal end, the second arm connected to the first arm. A first rake member is connected to the distal end of the first arm and has a first plurality of tissue engaging members extending therefrom to engage tissue. A second rake member is attached to the distal end of the second arm, the second rake member having a second plurality of tissue engaging members extending therefrom to engage tissue. A transverse bar can extend through the first and second rake members such that the first and second rake members movable along the transverse bar. Systems and methods for wound closure are also disclosed.

A surgical device for clipping tissue can include a replaceable cartridge comprising a stack of clips contained therein and a firing drive configured to reciprocatingly eject, or deploy, the clips from the cartridge. After the clips have been deployed from the cartridge, a blocking member can be positioned to impede or block the firing drive. In at least one embodiment, the cartridge can include a biasing member configured to bias the blocking member into a firing chamber defined in the cartridge and/or surgical device. The surgical device can also include a crimping drive configured to deform a clip after it has been ejected from the cartridge. The blocking member can also be configured to impede or block the crimping drive after all of the clips from the cartridge have been used.

The present disclosure provides methods and devices for wound closure. In some exemplary embodiments, a tissue approximation device is provided. In some embodiments, the tissue approximation device includes a first scissors arm having a proximal end and a distal end and a second scissors arm having a proximal end and a distal end. In some embodiments, the second scissors arm is connected to the first scissors arm at a pivot point. In some embodiments, the tissue approximation device further includes a first rake member connected to the distal end of the first scissors arm via a first articulating joint. In some embodiments, the first rake member includes a plurality of hooks configured to grip tissue.

This invention relates to devices that join a pair of edges. Previously, suture assemblies used holes perpendicular to a vertical plane. Embodiments of the present invention use a first pad tunnel (130) between a first pad lower plane opening (126) and a first pad upper plane opening (122). A first pad tunnel major axis (132) passes through a first pad upper plane opening center (124) and a first pad lower plane opening center (128). For reference a first pad orthogonal axis (134) passes through the first pad upper plane opening center (124) orthogonal to the first pad upper plane (118) and the first pad lower plane (120). A first pad angle (θ1) is measured clockwise from the first pad orthogonal axis (134) to the first pad tunnel major axis (132). The first pad angle is at least five degrees but no more than 175 degrees.

Apparatus and related methods for sequentially positioning and retaining opposing sides of a tissue wound. The apparatus includes a device body having a head portion for positioning between first and second sides of the wound, with the head portion defining first and second retention zones on opposed side of the head portion. The device body further includes first and second approximation arms. The device body further includes a trigger assembly defining three stages of operation. A first stage of operation positions the first approximation arm proximate the first retention zone. A second stage of operation positions the second approximation arm proximate the second retention zone with the first approximation arm remaining in approximation to the first retention zone. A third stage of operation advances a fastener into the first and second retention zones. In this manner, the apparatus sequentially positions the first and second sides with respect to the head portion.

There are shown and described embodiments of a closure device for closing holes in tissue, for example in the right atrial appendage. The closure device in particular embodiments includes first and second mesh closure members and a tether or stem connecting them. Embodiments of a delivery device for the closure device are also described.

An obesity treatment apparatus comprises at least one operable stretching device (10) implantable in an obese patient and adapted to stretch a portion (12a) of the patient's stomach wall (12), and an operation device (16, 18) for operating the stretching device when implanted to stretch the stomach wall portion such that satiety is created.

An endoscopic treatment tool includes: a needle tube in which a needle tube insertion passage extending from a distal end to a proximal end of the needle tube is formed; a stylet which is disposed to move freely in the needle tube insertion passage; a main manipulation part which is connected to a proximal end side of the needle tube, the main manipulation part supporting the stylet such that the stylet advances while rotating, and the main manipulation part operating the stylet; a manipulation transmission member which has flexibility and the manipulation transmission member is connected to the stylet; and an auxiliary manipulation part which includes a handle fixed to a proximal end portion of the manipulation transmission member and the auxiliary manipulation part is configured such that the manipulation transmission member advances while rotating in accordance with a manipulation of the handle.

Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

A medical device for at least partially covering and applying force on tissue includes a body having a spanning structure and struts respectively connected to lateral portions of the spanning structure. Inner ends of the struts extend into an area over which the medial portion of the spanning structure extends. The medical device is reconfigurable between extended and retracted configurations. The inner ends of the struts are closer to one another in the retracted configuration than in the extended configuration. The inner ends of the struts are closer to the medial portion of the spanning structure in the retracted configuration than in the extended configuration. Each strut includes an engagement zone configured to engage and apply force on the tissue, at least while the medical device is in the retracted configuration. A web can be connected to the struts and span between the inner ends of the struts.