A hemostatic vessel band is provided. The hemostatic vessel band has a membrane. A plurality of cells extend transversely from a membrane second surface. Each of the cells has a cell chamber that is defined by the membrane second surface and a plurality of cell walls. When the hemostatic vessel band is selectively fastened circumferentially about a vessel to at least partially cover the target site. The hemostatic vessel band applies radially inward pressure to at least a portion of the vessel and at least a portion of the target site. Each cell chamber that is positioned transversely adjacent to at least a portion of the target site forms one isolation zone of a plurality of isolation zones. Each isolation zone is at least partially isolated from each of the other isolation zones and from any vessel surface adjacent to the isolation zone.

Disclosed are apparatus and method for forming passage extending along a plane crossing an organ's volumetric region from an entry point to an opposing exit point at a surface of the organ, and for passing a tension member around the volumetric region by pulling the tension member from the exit point to the entry point through the passage. The apparatus can include a rigid outer tube with a tip for penetrating the organ and reach a penetration depth; an inner needle with elastic body configured to pass straightened through outer tube lumen and to partially protrude and voluntarily flex to a curved form greater than the diameter of the volumetric region; and a tension member passer with a pulling portion for engaging with portion of tension member and for pulling the tension member when withdrawn.

A fixation mechanism that more effectively limits or prevents relative movement between two adjacent objects includes an elongated tie having a free end and a joined end and a clasp coupled to the joined end of the tie. The clasp includes a housing having an insertion channel in which the free end of the tie is inserted and an exit channel through which the tie exits such that the tie and clasp form a loop that connects the two adjacent objects. The clasp further includes a locking mechanism positioned in the housing between the insertion channel and the exit channel. The locking mechanism includes a locking tine that permits the free end of the tine to pass forwardly through the insertion channel and out the exit channel but grips the tie to prevent it from moving rearwardly out of the housing.

An apparatus for controlling the movement of bile and/or gallstones in the biliary duct of a patient, that comprises an implantable constriction device for gently constricting (i.e. without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the movement of bile and/or gallstones in the biliary duct, and a stimulation device for stimulating the wall portion of the tissue wall. A control device controls the stimulation device to stimulate the wall portion, as the constriction device constricts the wall portion, to cause contraction of the wall portion constricted by the constriction device to further influence the movement of bile and/or gallstones in the biliary duct. The apparatus can be used for actively moving the gallstones in the lumen, with a low risk of injuring the biliary duct.

A method may include accessing a terminal branch of an ophthalmic artery through a face of a subject. Additionally, the method may include positioning a device within the ophthalmic artery of the subject and treating at least one of a blockage, a stenosis, a lesion, plaque or other physiology in at least one of the ophthalmic artery or a junction between an internal carotid artery and the ophthalmic artery.

Systems and methods for building a landing zone for an endovascular procedure are described. This procedure is “hybrid” in that it involves both direct access (e.g., sternotomy or partial sternotomy) to the site for installation of the landing zone, as well as endovascular installation of a TAVR or TEVAR device (e.g., stent graft) once the landing zone is installed. The landing zone is installed by wrapping a landing band around a portion of a vessel. The landing band may be selected to be fixed at a diameter so that it inhibits any expansion of the vessel, and also supports a later-installed TAVR or TEVAR device. The TAVR or TEVAR device is then endovascularly delivered to the vessel and deployed therein. The device expands until it contacts the vessel, which is supported from the outside by the landing band, which thus constrains and supports the device from outside.

An implantable restriction device includes a plurality of beads, a plurality of links joining the beads together, and a parking feature. Each bead in the plurality of beads includes a housing, a passageway extending through the housing, and at least one magnet disposed around the passageway. The plurality of links are slidably disposed in corresponding passageways of the beads such that the plurality of beads can transition between a constricted configuration and an expanded configuration. The parking feature can consistently position the at least one link relative to the housing in the contracted configuration.

Methods and devices are disclosed for treating neurovascular venous outflow obstructions, with or without implantation of a prosthetic valve. The valve may be carried by a support, such as a stent, which may be self-expandable or balloon expandable. Both transvascular and direct surgical access is contemplated.

An inflatable belt 100 for use in a BFR system with an outer belt material 102 hermetically sealed to an inner belt material 101 along a perimeter, thereby forming at least one inflatable chamber 103, the inflatable chamber having an input port 104 for accepting a gas into the chamber, the inflatable belt further comprising a first fastening means 110 in communication with the outer belt material, for attaching to a second fastening means 111 in communication with the outer belt material, thereby locking a circumference of the inflatable belt when wrapped around a user's limb, the inflatable belt providing sufficient volume and compliance so as to reduce spikes in pressure and thereby improve comfort and safety of the inflatable belt for use in restriction of blood flow for muscle development.

A device for accessing and removing a vermiform appendix without the need for surgical incisions may include a double-layered endotube fitted with electroceramic baffling; an endoscope extending through the endotube; instruments fitted within the endoscope and configured to interchangeably extend through at least one tool orifice in the distal end of the endoscope; an extension disk attached to a proximal end of the endotube; a controller operatively attached to the instruments through the extension disk, the controller configured to control and drive movement of the endotube, the endoscope, and the instruments; a casing attached to a distal end of the endotube; a pneumatic extensible cone housed within the casing, the pneumatic extensible cone configured to go from an undeployed position to a deployed position; and a cecoclosure device attached to the pneumatic extensible cone.