The invention relates surgical abdominal methods of treating obesity in a patient by implanting a volume filling device that, when implanted in a patient, reduces the food cavity in size by a volume substantially exceeding the volume of the volume filling device. Also disclosed is a laparoscopic instrument for providing a volume filling device to be invaginated in the stomach wall of a human patient to treat obesity.

An apparatus for treating obesity comprises a volume filling device formed by at least two segments and is provided and following implantation, the device is placed resting against the stomach wall of the patient to reduce the inner volume of the stomach, thereby affecting the patients appetite.

Techniques for blockage removal are provided, which may provide immediate and effective aid to a choking victim. A blockage removal device may comprise a mouthpiece disposed on an inlet. The inlet may be coupled to a chamber configured to hold a vacuum generated by a vacuum pump. A vacuum gauge may display information to a user, who may open or close a valve to provide or remove a vacuum to attempt to remove a blockage.

A tissue displacing and fastening device is provided for manipulating and fastening tissue together. The device includes a tissue displacing elements, which displaces tissue. A fold is formed from the displaced tissue and the tissue is fastened together to secure the fold.

A surgical instrument assembly is provided. In some embodiments, an example surgical instrument assembly includes a surgical instrument configured to pass through a guide tube having a proximal end and a distal end. The surgical instrument can include one or more arms configured to extend from the intermediate position, each arm having one or more joints positioned along the arm and an end effector attached at the distal end of each arm. The surgical instrument assembly can include a control assembly positioned at the proximal end and configured to control the movement of the joints and the end effectors.

Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.

A clipping system includes a pusher element, a holder mounted over an insertion device and clips stacked along a length of the holder. The holder includes a longitudinally channel.

Each clip extends along a curvature defining a tissue-receiving space therewithin and extends about the holder with an exterior surface of the holder holding the clip open with the first and second ends of the clip separated from one another to receive a tissue therein. Each clip is independently deployable from the holder so that, upon release of the clip from the holder, the clip reverts to a closed configuration. In the closed configuration, the first and second ends are moved toward one another to reduce a size of the tissue-receiving space so that tissue is gripped therewithin. The element is mounted over the holder and moved distally along the holder to independently deploy each clips.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Systems, instruments, and methods are described in which an apparatus comprises a housing including a scalpet device. The scalpet device includes a scalpet array that includes scalpets arranged in a pattern. The scalpets are deployable from the housing to generate incised skin pixels at a target site. The housing is positioned and the scalpet array is deployed into tissue at the target site. Incised skin pixels are generated when the target site is a donor site, and skin defects are generated when the target site is a recipient site. The incised skin pixels are harvested.

The disclosure provides a system that may acquire, via an image sensor, an image of an eye of a person; may determine a location of an iris of the eye from the image; may determine a position of a suction ring from the image; may display, via a display, the image; may display, via the display, a first graphic overlay on the image that indicates the location of the iris of the eye; may display, via the display, a second graphic overlay on the image that indicates the position of the suction ring; may determine multiple iris structures from the image; may determine an orientation of the eye based at least on the multiple iris structures from the image; and may display, via the display, information that indicates the orientation of the eye.