The present invention refers to a dural sealing system (100) comprising an implant (10), joined to a guiding thread (20); a transfer device (30), provided with a grip portion (30a) and a hollow portion (30b), said hollow portion (30b) terminating, at a first end, in a nozzle (30c) that can be coupled to an epidural needle (200), said hollow portion (30b) also terminating in a second end fitted with an entry region (30d); and an introductory device (70) comprising a tube (70a) with a hollow interior section, provided with a first free end and a second closed end, attached to a stop (70b).

Methods and devices for detecting positioning of a probe in a tissue of a patient. A method can include providing a detection device; advancing a device coupled probe through the tissue of the patient and toward the patient's target tissue; detecting a change in pressure about the distal portion of the coupled probe during advancing, where the detected pressure change indicates probe positioning in a vein or artery of the patient; outputting the detected pressure change or indication of probe positioning to a visual display.

Apparatuses and methods can be used to guide placement of needles within the body. For example, this document describes apparatuses that measure impedance and/or force as a needle is passed through tissue to inform user of which anatomical space they are in. Low-cost portable bedside electro-physical apparatuses and methods for needle guidance and confirmation of successful placement in portions of the human body such as vessels and thecal sac are described herein.

A portable and passive safety intraosseous device to allow for direct introduction of medications, etc., within the intermedullary space of a subject patient's bone or, if needed, the removal of certain substances from such a subject patient's bone. Such a device permits direct drilling and placement of a cannula within the subject bone with access external to the subject patient's skin, permitting, as well, connection of a tube for such introduction/removal purposes. The ability to provide a passive safety unit allows for facilitated utilization in, for instance, emergency situations with the entire device provided for utilization thereof. The device includes a drilling component with a permanently attached stylet and a removable cannula, a power supply for a single drilling operation, a mechanism to draw the stylet back into the drill component after use and disengagement from the cannula, and an automatic closure that activates with the separation of the cannula.

A medical assembly to assist physicians with holding and guiding multiple needles for medical procedures may include a targeter having a frame having two elongate parallel supports attached to one another by at least one adjustable central arm; and a plurality of ports attached to each elongate support, wherein the ports are each sized to accommodate a syringe needle. The ports may be attached to their respective support at an angle of 15. Moreover, the supports may each include a fastener to removably secure the targeter to a patient.

A medical instrument that includes a needle and an expandable member located at a distal end of the needle. The expandable member includes a blocking member. The expandable member is configured to move tissue away from a distal end of the needle and/or from a distal end of a tubular member that is in fluid communication with a substance source. A substance is configured to be expelled into the anatomy through the expandable member. The blocking member is configured to restrict or prevent the substance from being expelled through the portion of the expandable member that includes the blocking member.

A device for providing an implanted injection site capable of delivering a therapeutic substance or medication into the subarachnoid space. The receiving compartment is implanted under the skin adjacent the spine. Injections may be made repeatedly into the membrane for delivering the therapeutic substance without the need for repeated spinal taps. Medications such as immunoglobulin may be administered intrathecally directly into the central nervous system bypassing the blood brain barrier providing more concentrated, effective and less costly treatment of diseases such as Alzheimer's disease. Another embodiment is a method of administering an immunoglobulin composition having a four to six percent concentration incrementally over time by alternately removing cerebrospinal fluid and injecting the immunoglobulin composition.

A device for drawing spinal fluid from a body part or injecting medication into the body part is disclosed. The device may include one or more measurement features (markings) that indicate the subcutaneous depth of the device as well as confirm placement and orientation of the spinal fluid withdrawing or medication injecting end of the device in the body part. The device may include a trocar and a cannula having a patient end, a non-patient end, an outer surface, and a central passage adapted to receive said trocar. One or more windows may be provided in or on the cannula, said windows extending from the outer surface of the cannula to the central passage. The windows may be spaced from the patient end of the cannula and from each other along a specific longitudinal axis of the cannula by a predetermined distance, such as 10 millimeters. Means for venting air from the cannula central passage and/or transparent/translucent material may be disposed in said windows.

Insertion devices and associated systems and methods for the percutaneous placement of patient leads are disclosed herein. A system in accordance with a particular embodiment includes a cannula having a lumen and a first dilator. The first dilator can be positioned within the lumen and the first dilator and the cannula can be used to create a percutaneous entry point. An additional dilator can be positioned over the first dilator and advanced into the percutaneous entry point to expand the percutaneous entry point. A final dilator can be inserted into the patient and two leads can be advanced into the patient through the final dilator.

Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.