The present application is directed to excimer forming compounds of Formula I: WV[Y].sub.n wherein W is an excimer forming fluorophore, V is a linker moiety, Y is a metal ion coordinating moiety and n is 1, 2 or 3. In particular, the application is directed to excimer forming compounds for the detection of proximally phosphorylated sites including those found on polypeptides, proteins, pyrophosphate and RNA, for example in aqueous solution, polyacrylamide gels blotting membranes, solid-support assays and in cell culture samples.

The present invention discloses a two-dimensional nanomaterial dispersant, a preparation method of a two-dimensional nanomaterial by liquid phase exfoliation, and use thereof. The present invention utilizes a readily synthesizable and inexpensive oligoaniline, oligoaniline derivative, polyaniline conducting polymer or the like as a dispersant of a two-dimensional nanomaterial, such as a boron nitride nanosheet or a molybdenum disulfide nanosheet, simply mixes the dispersant with boron nitride or molybdenum disulfide in a dispersion medium, such as water, an organic solvent, or a polymer resin, and can significantly improve dispersity and dispersion stability of the two-dimensional nanomaterial in the dispersion medium by a physical interaction therebetween; and can also obtain the two-dimensional nanomaterial in the dispersant by a simple liquid phase exfoliation method, which is an environment friendly and efficient process with simple operations without impairing the physical structure and chemical properties of the two-dimensional nanomaterial, and facilitates large-scale implementation.

The present invention discloses a two-dimensional nanomaterial dispersant, a preparation method of a two-dimensional nanomaterial by liquid phase exfoliation, and use thereof. The present invention utilizes a readily synthesizable and inexpensive oligoaniline, oligoaniline derivative, polyaniline conducting polymer or the like as a dispersant of a two-dimensional nanomaterial, such as a boron nitride nanosheet or a molybdenum disulfide nanosheet, simply mixes the dispersant with boron nitride or molybdenum disulfide in a dispersion medium, such as water, an organic solvent, or a polymer resin, and can significantly improve dispersity and dispersion stability of the two-dimensional nanomaterial in the dispersion medium by a physical interaction therebetween; and can also obtain the two-dimensional nanomaterial in the dispersant by a simple liquid phase exfoliation method, which is an environment friendly and efficient process with simple operations without impairing the physical structure and chemical properties of the two-dimensional nanomaterial, and facilitates large-scale implementation.

This application relates to a method of detecting negatively charged phosphate-containing membranes and membrane components, such as in cell membranes or artificial lipid vesicles, and its use, for example, in detecting apoptosis and bacterial infection.

This application relates to a method of detecting negatively charged phosphate-containing membranes and membrane components, such as in cell membranes or artificial lipid vesicles, and its use, for example, in detecting apoptosis and bacterial infection.

A compound having an excellent rate of change in HTP caused by exposure is achieved and is represented by General Formula (1). In addition, a composition is formed of the compound, and a cured product, an optically anisotropic body, or a reflective film is obtained by curing the composition. ##STR00001##

The present invention provides a resin composition having a high sensitivity and serving to produce a cured film with a low water absorption rate. The resin composition includes: (a) an alkali-soluble resin and (b1) an amido-phenol compound containing a phenolic hydroxyl group in which a monovalent group as represented by the undermentioned general formula (1) is located at the ortho position and/or (b2) an aromatic amido acid compound containing a carboxy group in which a monovalent group as represented by the undermentioned general formula (2) is located at the ortho position:

##STR00001##

wherein in general formula (1), X is a monovalent organic group having an alkyl group that contains 2 to 20 carbon atoms and bonds directly to the carbonyl carbon in general formula (1) or a monovalent organic group that has (YO).sub.n; and in general formula (2), U is a monovalent organic group that has an alkyl group containing 2 to 20 carbon atoms and bonding directly to the amide nitrogen in general formula (2) or a monovalent organic group that has (YO).sub.n; wherein Y is an alkylene group containing 1 to 10 carbon atoms and n is an integer of 1 to 20.

The present disclosure provides novel compounds capable of functioning as Myoctye Enhancer Factor 2 (MEF2) modulators, as well as compositions, pharmaceutical formulations, methods of synthesis and kits. Also provided are methods of treating a condition regulatable by MEF2 and/or MEF2 cofactors using the compounds, compositions, pharmaceutical formulations, and kits provided herein.

The present invention discloses a two-dimensional nanomaterial dispersant, a preparation method of a two-dimensional nanomaterial by liquid phase exfoliation, and use thereof. The present invention utilizes a readily synthesizable and inexpensive oligoaniline, oligoaniline derivative, polyaniline conducting polymer or the like as a dispersant of a two-dimensional nanomaterial, such as a boron nitride nanosheet or a molybdenum disulfide nanosheet, simply mixes the dispersant with boron nitride or molybdenum disulfide in a dispersion medium, such as water, an organic solvent, or a polymer resin, and can significantly improve dispersity and dispersion stability of the two-dimensional nanomaterial in the dispersion medium by a physical interaction therebetween; and can also obtain the two-dimensional nanomaterial in the dispersant by a simple liquid phase exfoliation method, which is an environment friendly and efficient process with simple operations without impairing the physical structure and chemical properties of the two-dimensional nanomaterial, and facilitates large-scale implementation.

Novel 2,2-diaminobiaryls having two secondary amines and an electrochemical process for preparation thereof.