C07C271/52

POLYMER PHOTOPOLYMERIZATION SENSITIZER

To provide a photopolymerization sensitizer which will not cause problems of dusting or coloring of a cured product by bleeding of additives such as the photopolymerization sensitizer on the surface e.g. by blooming at the time of photo-curing or during storage of the cured product, and which imparts a practically sufficient photo-curing rate.

An oligomer of a 9,10-bis(substituted oxy)anthracene compound having repeating units represented by the following formula (1):

##STR00001##

wherein n represents a repetition number and is from 2 to 50, each of X and Y which may be the same or different, is a hydrogen atom, a C.sub.1-8 alkyl group or a halogen atom, and A is a bivalent substituent.

POLYMER PHOTOPOLYMERIZATION SENSITIZER

To provide a photopolymerization sensitizer which will not cause problems of dusting or coloring of a cured product by bleeding of additives such as the photopolymerization sensitizer on the surface e.g. by blooming at the time of photo-curing or during storage of the cured product, and which imparts a practically sufficient photo-curing rate.

An oligomer of a 9,10-bis(substituted oxy)anthracene compound having repeating units represented by the following formula (1):

##STR00001##

wherein n represents a repetition number and is from 2 to 50, each of X and Y which may be the same or different, is a hydrogen atom, a C.sub.1-8 alkyl group or a halogen atom, and A is a bivalent substituent.

ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER

An isocyanate composition according to the present invention contains an isocyanate compound of formula (1) and/or (2) (wherein R.sup.1 represents a hydrogen or a monovalent organic group, and R.sup.2 represents a monovalent organic group), and, relative to the total mass of the isocyanate compound in the composition, 1.0 ppm by mass to 10% by mass of a compound of formula (3): R.sup.13(COOR.sup.14)a (wherein R.sup.13 represents an organic group with a valence of a, R.sup.14 represents a monovalent organic group, and a represents an integer of 1 or 2), which is different from the isocyanate compound, and/or, 1.0 ppm by mass to 10% by mass of a compound having an UV absorption in an area of decamer or higher isocyanates in a measurement spectrum of gel permeation chromatography.

##STR00001##

BIOSYNTHESIS OF CANNABINOID PRODRUGS AND THEIR USE AS THERAPEUTIC AGENTS
20190382814 · 2019-12-19 ·

The present invention provides methods for producing cannabinoid prodrugs. Also described are pharmaceutically acceptable compositions of the prodrugs and a system for the large-scale production of the prodrugs.

MODULATORS OF THE EIF2ALPHA PATHWAY

Provided herein, inter alia, are compounds and methods useful for modulating the translational effects of eIF2 phosphorylation, the Integrated Stress Response (ISR), and the unfolded protein response (UPR); for treating diseases; for increasing protein production, and for improving long-term memory.

MODULATORS OF THE EIF2ALPHA PATHWAY

Provided herein, inter alia, are compounds and methods useful for modulating the translational effects of eIF2 phosphorylation, the Integrated Stress Response (ISR), and the unfolded protein response (UPR); for treating diseases; for increasing protein production, and for improving long-term memory.

PRODRUGS OF PHENOLIC TRPV1 AGONISTS
20190284132 · 2019-09-19 ·

Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

PRODRUGS OF PHENOLIC TRPV1 AGONISTS
20190284132 · 2019-09-19 ·

Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF

It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.

##STR00001##

Polyisocyanate composition and isocyanate polymer composition

The present invention relates to a polyisocyanate composition comprising, on the basis of the total mass of the polyisocyanate composition, 97 mass % or more of a polyisocyanate; and 2.0 mass ppm to 1.010.sup.4 mass ppm of a compound represented by the formula (1): ##STR00001## wherein R.sup.1 is an aliphatic group having 6 to 70 carbon atoms, R.sup.2 is an aromatic ring, a is an integer of 1 to 5, b is an integer of 0 to 4, and the sum of a and b is 2 to 5.