Barrett's esophagus is a serious complication of GERD. It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells (which are usually found lower in the gastrointestinal tract). A method comprising deploying multiple stents to cause pressure ischemia and subsequent necrosis of the mucosal layer of the esophagus which is affected with the Barrett's disease is disclosed. A pair of implantable stents having specific characteristics is disclosed which can be deployed in the esophagus to cause necrosis of the mucosal layer of the esophagus through induction pressure.

Systems and methods for forming a lesion on an endocardial tissue of a patients heart involve placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, and placing a guiding assembly outside of the heart. An ablation assembly includes an ablation element and a first attraction element, and a guiding assembly includes a second attraction element. First and second attraction elements can be attracted via magnetism. Techniques involve forming an ablation on the cardiac tissue of a patient's heart with an ablation element of the ablation assembly. Optionally, techniques may include moving the second attraction element of the guiding assembly relative to the patient's heart, so as to effect a corresponding movement of the ablation element of the ablation assembly.

Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

An ablation system comprises: an ablation catheter and a console. The ablation catheter comprises: a shaft including a proximal end, a distal portion and a distal end; an ablation element configured to deliver energy to tissue; and a force maintenance assembly comprising a force maintenance element and configured to control and/or assess contact force between the ablation element and cardiac tissue. The console is configured to operably attach to the ablation catheter and comprises: an energy delivery assembly configured to provide energy to the ablation element. Methods of ablating tissue are also provided.

Apparatus, including a catheter configured to be inserted into an organ of a human body. A plurality of electrodes are deployed on the catheter, the electrodes being configured to transfer radiofrequency (RF) ablation energy to tissue of the organ. The apparatus also includes a power supply configured to supply the RF ablation energy at a level of up to 100 W to each of the plurality of electrodes simultaneously, so as to ablate respective sections of the tissue of the organ in contact with the electrodes.

According to one aspect, a medical system may include an instrument including an end effector for acting as a monopolar electrode. The end effector may be configured to be positioned in a body of a subject and emit radiofrequency energy towards a target area in the body. The medical system may further include a return electrode. The return electrode may be deliverable within the body proximate the target area and separately from the instrument and the monopolar electrode. The return electrode may be configured to contact tissue in the body proximate the target area and receive radiofrequency energy emitted from the end effector.

In certain examples, aspects are directed to an ablation tool or other procedure-specific tool to treat or assess biological tissue (e.g., ablate cardiac tissue) having a first tissue side and a second, opposite tissue side at which a magnetic-draw element is to be located. In a specific example, a first magnetic element is associated with or coupled to a catheter tool having an expandable portion to transition from a first state towards a second state for providing an expanded girth, so that the expandable portion surrounds the first magnetic element and moves the procedure-specific tool, in part by the first magnetic element moving via magnetic attraction. While the first magnetic element and the magnetic-draw element align on either side of the biological tissue, the procedure-specific tool may be used for the procedure.

An ablation probe tip 100 having a shaft 102 with an insertion end 104 and an annular aperture 120 near the insertion end 104. A center of ablation 124 is located within the shaft 102 and surrounded by the annular aperture shaft 102. The ablation probe tip 100 may be part of an ablation probe system 50 that includes an ablation source 60 that provides ablation means 62 to the ablation probe tip 100. The center of ablation 124 is a focal region from which the ablation means 62 radiates through the annular aperture 120 to form an ablation zone 150, 160, 170. The system 50 has at least one intra-operative control selected from the group of: ablation zone positioning control, ablation zone shaping control, ablation center control, ablation zone temperature control, guided ablation volume/diameter control, and power loading control.

Disclosed herein are systems, devices, and methods for treating heart failure. In some variations, a catheter for forming an anastomosis in a heart may comprise a first catheter comprising an electrode. A second catheter may be slidably disposed within the first catheter. The second catheter may comprise a barb and a dilator comprising a mating surface configured to engage the electrode.

A corrugated radiofrequency ablation catheter having wall-attaching adjustment wires (6, 6A, 6B, 6A′, and 6B′), provided with a strip-shaped connecting catheter, an electrode frame provided at the front end of the connecting catheter, and a control handle (20) provided at the rear end of the connecting catheter. The electrode frame is a corrugated electrode frame consisting of one or more corrugations, where one or more electrodes (2) respectively are distributed on the corrugations. The rear sections of the wall-attaching adjustment wires (6, 6A, 6B, 6A′, and 6B′) are slidably provided within one lumen of the connecting catheter and are connected at the rear extremities (60) onto a control element (22) provided on the control handle (20) or connected onto a control element (22) provided outside of the control handle (20).