An endoscopic treatment device includes a hollow tube; an electrode; and an insulative support member. In a radial direction relative to a longitudinal axis of the hollow tube, the insulative support member is radially outward of the electrode and the hollow tube is radially outward of the insulative support member.

There is provided with a method of treating cancer. A chemokine is administered in combination with performing a hyperthermia on the cancer. This improves an effect of the hyperthermia on the cancer. Performing the hyperthermia includes locally heating the cancer.

Devices, systems, and methods for treating the pancreas are disclosed herein. For example, some aspects of the technology are directed to a method for treating a medical condition affecting the pancreas of a human patient, wherein the method comprises implanting an occlusive device within the pancreatic duct to induce atrophy of pancreatic tissue.

A fluid source on a carrier is configured to rotate relative to a probe to direct a fluid stream from the source toward an opening of an evacuation lumen. This may help to remove material that may collect near the opening, such as blood clots and tissue. Also, directing the fluid stream toward the evacuation lumen can draw flowable material from the surgical site toward the evacuation lumen to improve removal of material from the surgical site.

Medical instruments and systems for applying energy to tissue, and more particularly relates to a system for ablating, sealing, coagulating, shrinking or creating lesions in tissue by means of contacting a targeted tissue in a patient with a vapor phase media wherein a subsequent vapor-to-liquid phase change of the media applies thermal energy to the tissue to cause an intended therapeutic effect. Devices and methods for generating a flow of high-quality vapor and monitoring the vapor flow for various parameters with one or more sensors. Devices and methods for modulating parameters of the system in response to the observed parameters

An endoscope snare includes a sheath, a support wire inserted into the sheath and movable advance and retraction in the sheath along an axis, a loop-shaped conductive wire connected to a distal end of the support wire, and a pressing wire inserted into the sheath, connected to the conductive wire at a position different from that of the support wire, and movable advance and retraction in the sheath independently of the support wire. The pressing wire may have a plurality of wires, and may be connected to at least the conductive wire at two points of the support wire between which the axis is interposed.

A forceps includes an end effector assembly having first and second jaw members. One (or both) of the jaw members is moveable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One (or both) of the jaw members includes an opposed jaw surface having an electrically-conductive tissue sealing plate disposed thereon. The electrically-conductive tissue sealing plate includes a first portion configured to conduct energy through tissue grasped between the jaw members to create a main tissue seal and a second portion including a plurality of spaced-apart fingers extending from the first portion. The second portion is configured to conduct energy through tissue grasped between the jaw members to create an auxiliary tissue seal extending from the main tissue seal for reducing stress concentrations adjacent the main tissue seal.

An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.

An electrosurgical instrument having a radiating tip portion capable performing tissue ablation using microwave energy and electroporation (e.g. non-thermal irreversible electroporation) in a minimally invasive manner. The electrosurgical instrument may be used to perform microwave ablation and electroporation separately (e.g. sequentially) or simultaneously. The radiating tip portion may be dimensioned to be suitable for insertion into a pancreas via a surgical scoping device, to provide a rapid and accurate alternative to known RF ablation techniques. By enabling tumours within the pancreas to be treated using a minimally invasive procedure, it may be a viable option to use ablation and/or electroporation treatment for both curative as well as palliative reasons.

A method for analyzing biological samples using mass spectrometry or ion mobility spectrometry that includes producing gas-phase ions and neutrals from the sample in a proximity of the sample; transferring the produced ions from the sample to a distance via a flexible or re-configurable ion transfer device such that the flexible or re-configurable ion transfer device includes a plurality of electrodes configured to be flexible or flexibly connected to each other, and the ion transfer device is configured to be flexible while transferring the ions to allow the ion transfer device to form one or more curvatures; and separating the produced ions with a mass spectrometer or a mobility analyzer located at the distance to provide spectrometric results.