C07F7/081

Modulators of Sestrin-GATOR2 interaction and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

FUNCTIONALIZED FLUOROALKYL SILANE, AND SYNTHETIC METHOD THEREFOR AND APPLICATION THEREOF
20230257402 · 2023-08-17 · ·

Disclosed in the present invention are a functionalized fluoroalkyl silane compound and a synthetic method therefor. The method comprises: dissolving a halosilane and a fluoroalkyl source in an organic solvent; and synthesizing functionalized fluoroalkyl silane under the effect of an alkali or a tertiary phosphine compound. The functionalized fluoroalkyl silane can not only be used for constructing a series of high added-value compounds such as fluoroalkyl substituted alcohols, ketones and amines that can be constructed by conventional TMSR.sub.f, but also can transfer, by means of appropriate conversion, a functional group on a silicon protecting group to the obtained addition product in an addition reaction, for synthesizing some fluorine-containing compounds that cannot be synthesized by using a conventional TMSR.sub.f reagent, thereby greatly improving the synthesis efficiency and the atom economy of reactions. Also disclosed in the present invention are more excellent reaction efficiency and enantioselectivity, compared with conventional TMSCF.sub.3, exhibited by trifluoromethyl chloromethylsilane in synthesis of a 2-trifluoromethylquinoline compound and in an asymmetric trifluoromethylation reaction with α,β-unsaturated ketones.

Organic electroluminescent compound and organic electroluminescent device comprising the same

The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound of the present disclosure, an organic electroluminescent device having low driving voltage, high luminous efficiency, and/or improved lifespan characteristics can be provided.

Site-selective metal plating onto a package dielectric
11319334 · 2022-05-03 · ·

An integrated circuit (IC) package comprising a substrate having a dielectric, a first structure over at least a portion of the dielectric, the first structure comprising a molecular compound having a ligand coordinating moiety and a second structure over at least a portion of the first structure, the second structure comprising a metal, wherein the first structure is chemically bonded to the dielectric.

AQUEOUS CORROSION RESISTANT COATINGS WITH SURFACE-HYDROPHOBIC INORGANIC PARTICLES
20220127472 · 2022-04-28 ·

Aqueous coating compositions providing enhanced anticorrosive and water-resistant properties. The anticorrosive coating comprises water borne resin, surface-hydrophobic inorganic pigments, and/or surface-hydrophobic inorganic extenders.

Nitrogen-containing compound, electronic component using same and electronic device

The present disclosure belongs to the field of organic electroluminescent materials, and specifically relates to a nitrogen-containing compound, an electronic component using the nitrogen-containing compound and an electronic device using the nitrogen-containing compound. The nitrogen-containing compound has a structure as shown in Formula 1. When the nitrogen-containing compound of the present disclosure is used in an organic electroluminescent device, properties of the device can be effectively improved. ##STR00001##

Superomniphobic coatings and methods of preparation
11311907 · 2022-04-26 · ·

A composition useful for producing a superomniphobic coating on a substrate, the composition comprising a colloidal suspension of a fluorinated siloxane in a non-silicon-containing fluorinated solvent. In some embodiments, the composition further comprises particles of a hydrophobized metal oxide, e.g., silicon oxide, wherein the hydrophobized metal oxide may be fluorinated. In some embodiments, the composition further comprises a non-silicon-containing fluorinated polymer. The invention is also directed to methods for making the above composition. The invention is also directed to methods for using the above-described composition for rendering a substrate superomniphobic. The aforesaid method comprises depositing a liquid coating solution onto a substrate to form a coated substrate, followed by subjecting the coated substrate to a drying step to remove a liquid phase of the liquid coating solution, wherein the liquid coating solution comprises a colloidal suspension of a fluorinated siloxane in a non-silicon-containing fluorinated solvent.

Organic Light Emitting Display Device

An organic light emitting display device is provided. The organic light emitting display device may include at least one light emitting part between an anode and a cathode, and the at least one light emitting part having at least one organic layer and a light emitting layer, wherein the at least one organic layer comprises a compound represented by Chemical Formula 1 or 2.

THYROMIMETICS

Compounds provided herein function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their preparation.

COMPOUNDS HAVING ANTICANCER ACTIVITY

In one aspect, compounds and associated pharmaceutical compositions are described herein for the treatment of cancer. In some embodiments, for example, a pharmaceutical composition comprises a compound of Formula (I) in an amount sufficient to exhibit anti cancer activity.