A method for reshaping a nasal airway in a patient involves advancing an inflatable balloon of a reshaping device in an uninflated configuration into a nostril of the patient and between a nasal septum and a lateral wall of the nasal airway. The method then involves inflating the inflatable balloon to an inflated configuration to cause the inflatable balloon to contact nasal mucosa covering the nasal septum and the lateral wall, delivering energy from an energy delivery member attached to or inside of the inflatable balloon, and removing the reshaping device from the nasal airway.

An endometrial ablation tool is configured for modified endometrial ablation, rather than global endometrial ablation. The tool can work according to various different methodologies including ablation by thermal energy (hot or cold), ablation by RF energy, ablation by microwave energy, ablation by plasma gas heating or ablation by other endometrial contact methodologies for ablation thereof. The ablation tool is shaped so that it avoids ablation in cornual areas. In one embodiment, the tool is configured with a unique posterior and anterior portion, with only one such portion configured to perform ablation, so that ablation occurs only with the anterior endometrium or only the posterior endometrium.

A method for reshaping a nasal airway in a patient involves advancing an inflatable balloon of a reshaping device in an uninflated configuration into a nostril of the patient and between a nasal septum and a lateral wall of the nasal airway. The method then involves inflating the inflatable balloon to an inflated configuration to cause the inflatable balloon to contact nasal mucosa covering the nasal septum and the lateral wall, delivering energy from an energy delivery member attached to or inside of the inflatable balloon, and removing the reshaping device from the nasal airway.

A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to heat tissue to create lesions without ablating the tissue. The system includes a first treatment device having at least one electrode for applying radiofrequency energy to tissue, a controller including a connector to which a first treatment device is coupled for use, and a generator for applying radiofrequency energy to the electrodes. The controller controls application of energy so that the tissue is thermally treated to create lesions but preventing thermal treatment beyond a threshold which would ablate the tissue.

Systems and methods for treatment of tissue including an expandable member designed to be positioned at a site of interest against tissue to be treated and to accommodate fluid set at a temperature range to affect the tissue at the site of interest; an assembly for directing the fluid set at the temperature range into the expandable member, the assembly having an input to introduce the fluid into the expandable member to circulate substantially along an entire length of the expandable member and an output spatially situated from the input to permit fluid flow to be removed from within the expandable member; and a mechanism designed to direct fluid along the assembly and through the input into the expandable member while simultaneously removing fluid from the expandable member through the output, so as to maintain substantially constant fluid pressure within the expandable member.

In an illustrative embodiment, systems and methods for treating kidney disease in a human patient are disclosed. A method includes advancing a collapsible array of RF electrodes through a urinary tract of the patient in collapsed form and into a position in or near a renal pelvis. The effector is deployed to an expanded form to engage at least a portion of an interior wall of the renal pelvis. RF energy delivered through the array of electrodes target afferent nerves proximate the interior wall of the renal pelvis to inhibit or destroy their function. eGFR of the patient can be raised after treatment according to the method.

A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

Apparatus, systems, and methods provide access to the renal pelvis of a kidney to treat renal nerves embedded in tissue surrounding the renal pelvis. Access to the renal pelvis may be via the urinary tract or via minimally invasive incisions through the abdomen and kidney tissue. Treatment is effected by exchanging energy, typically delivering heat or extracting heat through a wall of the renal pelvis, or by delivering active substances.

A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.

A tissue ablation device is provided including an inflatable balloon with a cavity. The tissue ablation device further includes a catheter with a lumen in fluid communication with the cavity of the inflatable balloon. The lumen of the catheter is configured to deliver a fluid to the cavity thereby causing the inflatable balloon to inflate and expand. The device also includes a heating element connected to the balloon, wherein the heating element is further connected to an electrical source. The heating element is configured to receive an electrical current from the electrical source. Further, the heating element is configured to raise the temperature of the inflatable balloon and the fluid when an electrical current is passed through the heating element.