The present disclosure relates to a polycarbonate and a preparation method thereof, which has a novel structure with an improvement in weather resistance and refractive index, while having excellent mechanical properties.

Provided is a polycarbonate-based resin having a ratio of an amine terminal to all terminal groups of 1.0 mol % or more.

Provided is a polycarbonate-based resin composition, including: 50 mass % or more to 99 mass % or less of a polycarbonate-based resin (S) containing 0.1 mass % or more to 100 mass % or less of a polycarbonate-polyorganosiloxane copolymer (A), which contains a polycarbonate block (A-1) formed of a specific repeating unit and a polyorganosiloxane block (A-2) containing a specific repeating unit, and 0 mass % or more to 99.9 mass % or less of an aromatic polycarbonate-based resin (B) except the polycarbonate-polyorganosiloxane copolymer (A); 1 mass % or more to 50 mass % or less of a polyester-based resin (C); and 0.001 part by mass or more to 1 part by mass or less of an amide compound (D) with respect to 100 parts by mass of a total amount of the polycarbonate-based resin (S) and the polyester-based resin (C).

A multilayer body includes at least one layer (A) made of a polycarbonate resin (A) whose main repeating units include a unit (a-1) composed of an ether diol residue represented by the following formula (1) and a unit (a-2) composed of a diol residue represented by the following formula (2), and at least one layer (B) containing an aromatic polycarbonate resin (B), wherein the molar ratio of the unit (a-1) is 50 to 96 mol % and the molar ratio of the unit (a-2) is 4 to 50 mol %, with respect to 100 mol % of the total repeating units of the polycarbonate resin (A) and the proportion of the aromatic polycarbonate resin (B) in the layer (B) containing an aromatic polycarbonate resin (B) is 30% by weight or more, and the multilayer body is excellent in heat resistance, impact resistance, surface hardness, adhesion, and chemical resistance.

##STR00001##

In the formula (2), R.sup.1 and R.sup.2 each independently represent at least one group selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl group having 1 to 10 carbon atoms, an alkoxy group having 1 to 10 carbon atoms, a cycloalkyl having 6 to 20 carbon atoms, a cycloalkoxy group having 6 to 20 carbon atoms, an alkenyl group having 2 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, an aralkyl group having 7 to 20 carbon atoms, an aralkyloxy group having 7 to 20 carbon atoms, a nitro group, an aldehyde group, a cyano group, and a carboxyl group, and when a plurality of R.sup.1 and R.sup.2 are present, they may be the same or different; a and b each represent an integer of 1 to 4; and W represents at least one bonding group selected from the group consisting of a single bond and a bonding group represented by the following formula (3).

##STR00002##

In the formula (3), R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.1, R.sup.9, and R.sup.10 each independently represent at least one group selected from the group consisting of a hydrogen atom, an alkyl group having 1 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, and an aralkyl group having 7 to 20 carbon atoms, and when a plurality of R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, and R.sup.10 are present, they may be the same or different; R.sup.11, R.sup.12, R.sup.13, and R.sup.14 each independently represent at least one group selected from the group consisting of an alkyl group having 1 to 10 carbon atoms, a cycloalkenyl group having 6 to 20 carbon atoms, an alkenyl group having 2 to 10 carbon atoms, an aryl group having 6 to 10 atoms, and an aralkyl group having 7 to 20 carbon atoms, and when a plurality of R.sup.11,

Disclosed in the present disclosure is a biodegradable amphiphilic polymer containing disulfide in the side chain, a self-crosslinked polymeric vesicle thereof and an application in the targeted therapy of lung cancer. The polymer is obtained by an activity-controllable ring-opening polymerization based on a cyclic carbonate monomer containing a functional group of dithiolane ring, which has a controllable molecular weight and a narrow molecular weight distribution, and does not require processes of protection and deprotection; the polymer obtained by the ring-opening polymerization of the cyclic carbonate monomer of the present disclosure has biodegradability and can be used to control the drug release system, the prepared lung cancer-targeted reduction-sensitive reversibly-crosslinked polymeric vesicle as a nanomedicine carrier supports stable long circulation in vivo. However, it is highly enriched in lung cancer tissues, enter cells efficiently, and rapidly decrosslinks in the cells to release drugs, so as to kill cancer cells with high potency and specificity and inhibit the growth of tumor effectively without causing toxic and side effects.

The present disclosure relates to a composition that includes

##STR00001##

where A includes at least one of a carbon-carbon bond or a bridging group, R includes between 0 and 4 of a first hydrocarbon, and n is between 2 and 3,000. In some embodiments of the present disclosure, the bridging group may include a linear hydrocarbon chain and/or a branched hydrocarbon chain. In some embodiments of the present disclosure, the bridging group may include between 1 and 10 carbon atoms.

Techniques regarding the synthesis of one or more polymers through one or more ring-opening polymerizations conducted within a flow reactor and facilitated by one or more anionic catalysts are provided. For example, one or more embodiments can comprise a method, which can comprise functionalizing, via a post-polymerization reaction within a flow reactor, a chemical compound by covalently bonding a trimethylsilyl protected thiol to a pendent functional group of the chemical compound in a presence of a catalyst. The pendent functional group can comprise a perfluoroaryl group and a methylene group.

A copolycarbonate includes 0.005-0.1 mole percent of sulfur-containing carbonate units derived from a sulfur-containing bisphenol monomer, 2-95 mole percent of high heat carbonate units derived from a high heat aromatic dihydroxy monomer, and 5-98 mole percent of a low heat carbonate units derived from a low heat aromatic monomer, each based on the sum of the moles of the carbonate units; and optionally, thioether carbonyl endcaps of the formula C(O)-L-SR, wherein L is a C.sub.1-12 aliphatic or aromatic linking group and R is a C.sub.1-20 alkyl, C.sub.6-18 aryl, or C.sub.7-24 arylalkylene; wherein the sulfur content of the high heat copolycarbonate in the absence of the thioether endcaps is from 5-20 parts per million by weight.

An endcapped polycarbonate, comprising thioether carbonyl endcaps of the formula

##STR00001##

wherein L is a C.sub.1-12 aliphatic or aromatic linking group, and R is a C.sub.1-20 alkyl, C.sub.6-18 aryl, or C.sub.7-24 arylalkylene.

A process for producing a three-dimensional object by selectively layer-by-layer solidification of a powdery material layer at the locations corresponding to the cross-section of the object in a respective layer by exposure to electromagnetic radiation. The powdery material comprises at least one polymer which is obtainable from its melt only in substantially amorphous or completely amorphous form, or a polyblend which is obtainable from its melt only in substantially amorphous or completely amorphous form. The powdery material has a specific melting enthalpy of at least 1 J/g.