An assembly for imaging and/or treating brain tissue, having at least one acoustic window which comprises a plate that is transparent to ultrasonic waves, and at least one positioning marker which facilitates positioning of a probe for generating ultrasonic waves so as to be aligned with said acoustic window.

Embodiments relate to transformative shape-memory polymer tissue cavity markers and corresponding systems and deployment methods. In one embodiment, a tissue cavity marker for delivery to a tissue cavity via a minimally invasive surgical incision includes a transformative body having a first three-dimensional shape in a permanent state and a second three-dimensional shape different from the first three-dimensional shape in a temporary state, the transformative body comprising a shape-memory polymer material and being automatically transformable between the temporary state for delivery to a tissue cavity and the permanent state for residence within the tissue cavity by application of a stimulus; and at least one radiopaque marker coupled to the transformative body.

Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.

Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.

In some examples, a lead identification system includes a first set of first lead indicators and a second set of second lead indicators. Each of the first lead indicators is configured to removably attach to at least one of a first therapy delivery element, a first epidural needle, or a first connector to uniquely identify at least one of the first therapy delivery element, the first epidural needle, or the first connector during implantation of the first therapy delivery element in the patient. Each of the second lead indicators is configured to removably attach to at least one of a second therapy delivery element, a second epidural needle, or a second connector to uniquely identify at least one of the second therapy delivery element, the second epidural needle, or the second connector during implantation of the second therapy delivery element in the patient.

A marker for use in the lung of patients for marking the position of a lesion in the lung, wherein the marker comprises a self-expandable structure capable of self-expanding when released from a constricting device so as to implement marking function. Because the marker for use in the lung of a patient employs the self-expandable structure, when the position of a lesion is detected during a lung examination, the marker can be delivered to the position of the lesion via a catheter or a delivering device and substantively pressed and fixed by the lung when expanded at the lesion positions; as such, the lesion position can be located quickly by a surgeon during a surgery, the surgery time is shortened, the area of resection is reduced, and the post-surgery quality of life is improved for a patient.

Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.

A medical instrument configured to be inserted into a body cavity comprises a body comprises a first probe at a first end, the first probe comprising a first cylindrical portion with a first outer circumferential surface of a first diameter; a first circumferential edge at a distal end of the first probe; a first distal lip projecting outwardly from the first outer circumferential surface beyond the first circumferential edge and extending for at least a part of a circumference of the first circumferential edge; and a first marker lip projecting outwardly from the first outer circumferential surface and extending for at least a part of a circumference of the first outer circumferential surface; wherein the first distal lip is positioned distal to the first marker lip; and wherein the body comprises a hollow cavity to enable a second medical instrument to pass therethrough.

An implant system for restoring and improving physiological intracardiac flow in a human heart is provided including an implant for positioning at least partially in the atrium, partially within the atria-ventricular valve, and partially in the ventricle of the human heart and defining a contact surface; a base plate secured to the apex of the heart; a tether assembly connecting the implant to the base plate; and a sensor positioned on at least one of the implant, the base plate, and the tether assembly.

A method of marking lesions is disclosed herein. The disclosed method may assist surgeons localize small nodules by marking the nodules with a fiducial coil soaked with a fluorescent dye. In some preferred embodiments, the fiducial coil is placed at the time of biopsy using a robotic surgery system. In alternate embodiments, non-robotic peripheral navigation platforms may also be used effectively as an adjunct to surgical resection. The dye marks the location of a nodule, making it visible and palpable at the time of surgery. A surgeon may then target cancerous tissue with greater precision. The disclosed method allows a fiducial coil to be placed several days prior to surgery.