A single-insertion, multiple sampling biopsy device for insertion into a host includes an outer cutting cannula that has an inner lumen, a cutting distal end, and a proximal sample receiving port. The device includes a stylet extending at least partially within the inner lumen of the outer cutting cannula and along a longitudinal axis of the outer cutting cannula. A sheath extends at least partially within the inner lumen of the outer cutting cannula. A stylet tip is attached to a stylet rail. Each of the sheath and the stylet rail extends along the longitudinal axis. The stylet tip extends in the distal direction beyond the distal end of the outer cutting cannula. A drive unit is configured to translate each of the cutting cannula, the sheath, and the stylet relative to the stylet tip in proximal and distal directions. The stylet rail remains stationary relative to the drive unit.

An implant can include a flexible body made of a non-bioresorbable hydrogel material. The implant can also include a radiopaque marker located within the flexible body, where the body and the radiopaque marker can be implanted in a body cavity to mark the cavity in a radiographic image of the cavity.

Systems and methods for tracking movement of an anatomical element are provided. A marker may be coupled to an anatomical element and may be tracked by a navigation system. Movement of the marker may be detected by the navigation system and a pose of the marker may be determined based on the movement. The pose of the marker may be validated when the pose substantially matches a desired predetermined pose.

A device for providing a fiducial marker(s) within or near a target tissue (e.g. nodule, tumor or other) within a patient. The present teachings provide a system that includes a handle device, a catheter having a proximal end and a distal end, wherein the proximal end of the catheter is coupled to the handle device, and a monolithic material slidably received within the catheter. The monolithic material includes a stylet comprising a proximal end and a distal end, a fiducial marker having a proximal end and a distal end, and a failure section that mechanically couples the distal end of the stylet to the proximal end of the fiducial marker. The fiducial marker is configured to transition from having a first shape state inside the catheter to having a second shape state upon expulsion from the distal end of the catheter. The failure section is configured to mechanically fail in response to experiencing a heat value greater than a predefined threshold.

A method for marking a biopsy site after a biopsy has been performed includes the steps of placing a marker in the form of a semi-permeable membrane at the biopsy site so that the marker can be found at a later time, inserting a needle into the marker at the later time which is preferably immediately before a planned surgical resection of the biopsy site, and injecting a dye directly into the marker to color the marker. The semi-permeable qualities of the marker facilitate the slow egress of dye into tissue that is immediately adjacent the marker, enlarging the footprint of the marker. The semi-permeable membrane includes a high percentage of water after reaching osmotic equilibrium, rendering the marker highly visible under ultrasound imaging. The semi-permeable membrane may take the form of a fully or partially dehydrated hydrogel.

A biopsy marker having a spring-loaded anchor. The biopsy marker includes an insertion orientation and an anchored orientation. In the insertion orientation, the biopsy marker is manipulated under force to reduce the lateral span/cross-sectional area of the marker. In the anchored orientation, the biopsy marker is released and free to actively spring into a configuration in which the lateral span/cross-sectional area is greater than the lateral span/cross-sectional area of the biopsy marker when in the insertion orientation. In an embodiment, the spring-loaded anchor is configured to spring about a predefined rotational axis. An embodiment of the biopsy marker may be comprised of a single wire construction.

A biopsy marker having a spring-loaded anchor. The biopsy marker includes an insertion orientation and an anchored orientation. The lateral span/cross-sectional area of the marker is configured to change when transitioning between the insertion orientation and the anchored orientation. In an embodiment, the spring-loaded anchor is configured to spring about a predefined rotational axis. An embodiment of the biopsy marker may be comprised of a single wire construction.

Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.

A gold marker recovery device for radiotherapy positioning and its using method comprises a positioning gold marker and a recovery clamp, the positioning gold marker comprises a gold marker body and an elastic fixed structure, the elastic fixed structure comprises a fixed segment, an extending segment and a spiral segment connected in sequence; the fixed segment is embedded in the gold marker body so that the fixed segment is closely connected with the gold marker body, A magnetic ball is arranged at one end of the gold marker body away from the extending segment; the recovery clamp comprises an operating handle, the rear end of the operating handle is connected with an outer sheath tube in a hollow structure, and the outer sheath tube is connected with a zipper for driving the clamp to open and close.

Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.