Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

A compact handheld optical coherence tomography (OCT) spectrometer according to an embodiment of the present disclosure includes: a spectrometer optical module; a sensor board coupled to one side of the spectrometer optical module and including a sensor that converts light received from the spectrometer optical module into an electrical signal; and a connector configured to supply, to the sensor board, a control signal and a power signal received from another circuit outside the spectrometer and to transmit a signal received from the sensor board to another external circuit, and the sensor board is packaged with the spectrometer optical module, and the sensor is not indented but is formed to protrude from the surface of the sensor board, and a light receiving portion of the sensor is configured to face the inside of the packaged component and collect light from the spectrometer optical module.

A nervous tissue imaging system and a method therefor. The system includes: a housing containing an excitation light source, optically coupled with a source optical train, the excitation light source emits excitation light in a first wavelength range, which can be in a near ultraviolet light range, to illuminate a tissue region of interest including healthy nervous tissue and healthy non-nervous tissue. The excitation light in the first wavelength range causes the healthy nervous tissue, in response to being illuminated with the excitation light, to endogenously autoflouresce and emit first autofluorescence light at a first luminance in a second wavelength range. The healthy non-nervous tissue, in response to being illuminated with the excitation light, either avoids emitting any autofluorescence light in the second wavelength range; or endogenously autoflouresces and emits second autofluorescence light in the second wavelength range at a second luminance that is lower than the first luminance.

A portable device for the analysis of skin traumas is disclosed, the device allowing the medical professional to evaluate and analyze the healing process of the skin traumas, providing the medical professional with the temperature parameters, distance parameters and diagnosis parameters related to the skin trauma. By using the proposed portable device, it is possible, for example, to evaluate if the dimensions of the skin trauma have changed throughout the time, and also to generate a temperature map of the skin trauma as well as a history of conducted analyses. The present invention further discloses a method for analyzing skin traumas by using a portable device.

An intelligent portable medical instrument has an information processing unit and a data storage unit which are connected to a measurement and human body data collection unit. The measurement and human body data collection unit measures electrical, chemical, and acoustic data and sends the data to the information processing unit. The information processing unit compares the measured human physiological index data with the standard ranges of values and makes a preliminary health diagnosis opinion. The preliminary health diagnosis opinion and the measured data are transmitted to an in vitro unit which preferably uploads the information to a cloud server. The in vivo portion of the intelligent portable medical instrument is provided by a single integrated circuit.

The invention features methods for detecting the hydration state or vascular volume of a subject using a device capable of nuclear magnetic resonance (NMR) measurement. The methods involve exposing a portion of a tissue of the subject in vivo to a magnetic field and RF pulse from the device to excite hydrogen nuclei of water within the tissue portion, and measuring a relaxation parameter of the hydrogen nuclei in the tissue portion, the relaxation parameter being a quantitative measure of the hydration state or vascular volume of the subject as a whole. The invention also features devices and computer-readable storage media for performing the methods of the invention.

Methods and systems provide a non-ionizing alternative to conventional mammography X-ray techniques, which expose patients to ionizing radiation, for breast cancer tumor detection, using a miniaturized (wafer scale) array of ultra wide band (UWB) radio frequency (RF) sensors operating at 60 GHz (non-ionizing—no X-ray type accumulative radiations) that have capability to use both linear and polarized sensors, tomography, and suppression of scattering for improved imaging. Coding techniques provide significant processing gain that is essential for the large attenuation of transmitted signals in breast tissue operating at these high frequencies. The increased bandwidth of UWB RF detection provides better depth resolution of breast and body tissue. Using polarization improves detection of abnormal tissues. An extremely miniaturized (wafer scale) cluster of transmitter and receiver antenna elements improves detection at deeper parts of the breast and can detect cancerous cells in dense breasts often not picked up by mammography.

A surgical robot includes a robotic arm, a cart supporting the robotic arm and including a steering assembly. The steering assembly comprises wheels and a handle. The handle is moveable to a first position, a second position, and a third position. The steering assembly is configured such that the wheels allow the cart to roll in a longitudinal direction when the handle is in the first position, the wheels allow the cart to be roll a rotational direction when the handle is in the second position, and the wheels allow the cart to roll in a lateral direction when the handle is in the third position.

Disclosed herein is an uroflowmeter which includes: a sensor having a signal transmitter transmitting an input signal to a detection area and a signal receiver receiving an echo signal reflected from urine passing through the detection area; a signal processing unit calculating uroflowmetry data based on a difference between the input signal and the echo signal, the uroflowmetry data being data about a flow of the urine passing through the detection area; and a diagnosis unit diagnosing urinary disorders of a test subject by comparing the uroflowmetry data calculated by the signal processing unit with preset reference uroflowmetry data.

Methods and systems for performing computer-assisted image-guided surgery, including robotically-assisted surgery. A method of displaying image data includes displaying image data of a patient on a handheld display device, tracking the handheld display device using a motion tracking system, and modifying the image data displayed in response to changes in the position and orientation of the handheld display device. Further embodiments include a sterile case for a handheld display device, display devices on a robotic arm, and methods and systems for performing image-guided surgery using multiple reference marker devices fixed to a patient.