The present disclosure relates to detergents and cleaning agents comprising at least one protease and at least one organic compound of the formula (I) which acts as a protease inhibitor and therefore is a suitable enzyme stabilizer, and to the use of said compounds as enzyme stabilizers in protease-containing detergents and cleaning agents. The present disclosure also relates to the corresponding washing and cleaning methods and to the use of the detergents and cleaning agents.

The disclosure relates to the use of inorganic oxides, hydroxides or oxyhydroxides in enzyme-containing detergents or cleaning agents in order to increase enzyme stability as well as to an enzyme-containing detergent or cleaning agent, in particular a liquid detergent or cleaning agent having greater enzyme stability.

The present invention relates to methods for obtaining protease variants with improved properties. The present invention also relates to protease variants, compositions comprising the protease variants and methods of using the protease variants.

An encapsulated cleaning composition includes a core cleaning composition and a water-soluble film disposed about the core cleaning composition. The core cleaning composition itself includes an ionic liquid, water present in an amount of from 10 to 50 parts by weight per 100 parts by weight of the core cleaning composition, and at least one of a chelant, an enzyme, and a surfactant. The water-soluble film has a disintegration time of less than 90 seconds as determined at 40° C. using distilled water according to MSTM 205, when disposed about the core cleaning composition. The water-soluble film also remains stable for 6 months at 25° C., when disposed about the core cleaning composition.

Liquid stable enzyme compositions and methods of employing the same for cleaning, including warewashing and dishwashing, are disclosed. The stable enzyme compositions preferably employ an amphoteric surfactant stabilizing agent, such as disodium camphodiacetate (CADA), to stabilize a mixture of traditionally unstable enzymes, such as proteases and lipases.

The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.

Disclosed herein are compositions comprising a nonionic surfactant and one or more inherently stable subtilisin, and methods related to the use of such compositions for the cleaning of medical and dental instruments.

The present invention relates to a compound for stabilizing enzymes, the use of said compound for stabilizing an enzyme, a composition comprising said compound, a method of preparing the composition comprising said compound, a detergent composition comprising said compound and a method of preparing said compound.

A liquid cleaning agent containing: a) 20 to 70 wt % water, b) at least one amylase preparation, c) at least one Ca.sup.2+-ion source, d) lactic acid or a lactic acid salt, is notable for elevated amylase stability and improved cleaning performance.

The aim of the invention is to improve the primary detergent power of detergents and cleaning products, in particular with respect to soiling containing oil and/or grease. For this purpose, polymers comprising N-vinyl imidazole-derived betaine units are incorporated into the products.