Provided is a flex-PCB catheter device that is configured to be inserted into a body lumen. The flex-PCB catheter comprises an elongate shaft, an expandable assembly, a flexible printed circuit board (flex-PCB) substrate, a plurality of electronic components and a plurality of communication paths. The elongate shaft comprises a proximal end and a distal end. The expandable assembly is configured to transition from a radially compact state to a radially expanded state. The plurality of electronic elements are coupled to the flex-PCB substrate and are configured to receive and/or transmit an electric signal. The plurality of communication paths are positioned on and/or within the flex-PCB substrate. The communication paths selectively couple the plurality of electronic elements to a plurality of electrical contacts configured to electrically connect to an electronic module configured to process the electrical signal. The flex-PCB substrate can have multiple layers, including one or more metallic layers. Acoustic matching elements and conductive traces can be includes in the flex-PCB substrate.

The instant invention is a medical electrode comprising: an electrolyte; an absorbent material being in contact with the electrolyte, said absorbent material comprising a plurality of strands such that each strand is infused with the electrolyte; a pressing means being in contact with the absorbent material, said pressing means comprising a plurality of protrusions to push the strands of the absorbent material through the stratum corneum of a target skin area on a patient; and an electrically conductive means located adjacent to the pressing means, said electrically conductive means being in contact with the absorbent material. The instant medical electrode system achieves reduction of skin impedance at the site where the electrode is placed and generates low baseline noise, enabling accurate measurement of small or weak signals (FIG. 1).

A catheter includes a shaft for insertion into an organ of a patient, an expandable distal-end assembly, and at least an electrical interconnection. The expandable distal-end assembly is coupled to the shaft and includes multiple splines, at least one of the splines includes a flexible substrate, which is configured to conform to tissue of the organ. The electrical interconnection has: (i) a first section, which is formed within the flexible substrate and is configured to conduct ablation signals, and (ii) a second section thicker than the first section, which is formed over an outer surface of the flexible substrate and is configured to apply the ablation signals to the tissue.

Disclosed here are devices, systems, and methods for continuous monitoring of biomarkers using a wearable, non-intrusive microneedle sensor patch platform. In some aspects, a wearable, non-intrusive microneedle sensor device includes a microneedle sensor unit couplable to an electronics unit, where the microneedle sensor unit comprises a substrate, an array of spiked microneedle structures configured as electrochemical sensor electrodes, an array of base structures that encase a lower portion of spiked microneedle structures, and electrical interconnections that electrically couple the electrodes to the electronics unit for processing of detectable signals associated with one or multiple biomarkers in a biofluid.

A system for achieving optimal sensor placement and enhanced signal quality for monitoring maternal and fetal activities is disclosed. The system includes a monitoring device and a computing unit. The monitoring device is configured for monitoring maternal and fetal activities and providing guidance to the user via the computing unit upon detecting a feature of interest. The monitoring device includes a plurality of sensors, a data acquisition and transmission unit, one or more reference electrodes, and a ground electrode. Based on personal data acquired using the computing unit, the system utilizes a statistical or machine learning model which incorporates one or more subsets of the personal data to determine the optimal sensor placement close to the fetal heart position. Following sensor placement, the monitoring device performs a signal quality assessment and selects the optimal sensors to ensure reliable information on maternal and fetal activities is obtained.

Endoscopes and methods of their use, where the endoscopes provide a low profile or cross-section which facilitates introduction through small body passages, such as patient's cervix, and into body cavities, such a patient's uterus.

A surgical instrument includes a housing having a shaft extending therefrom for supporting an end effector assembly. A handle is disposed on the housing and is selectively moveable relative thereto to actuate the end effector assembly. A PCB is disposed within the housing and includes one or more accelerometers and a timing circuit having a first timer. The accelerometer is configured to activate the first timer of the timing circuit upon detecting movement of the surgical instrument after the surgical instrument is coupled to an electrosurgical energy source. A deactivating assembly is disposed within the housing and is operably associated with the timing circuit such that after expiration of the first timer, the deactivation assembly mechanically decommissions the surgical instrument for continued or subsequent use.

A smart ring includes a curved housing having a U-shape interior storing components including: a curved battery approximately conforming to the curved housing, a semi-flexible PCB approximately conforming to the curved housing and having mounted thereon: a motion sensor for generating motion data from physical perturbations of the smart ring, a memory for storing executable instructions, a transceiver for sending data to a client computer, a temperature sensor, and a processor for receiving motion data and performing executable instructions in response thereto, and a potting material disposed in the interior, forming an interior wall of the smart ring, wherein the potting material encapsulates the components and is substantially transparent to visible light, infrared light, and / or ultraviolet light.

The wearable article 200 comprises a sensing component. The electronics module 100 is removably coupled to the wearable article 200. The electronics module comprises a housing and a processor disposed within the housing 101. An interface element 121, 123 interfaces with the sensing component so as to receive signals from the sensing component and provide the same to the processor. A sensor 105 is disposed within the housing 101. The sensor 105 monitors a property of the environment external to the electronics module 100 through the housing 101. The housing 101 is constructed such that the sensor 105 has line of sight through the housing 101.

The electronics module (100) comprises a housing (101) comprising an opening (17). A processor (109). A flexible electronics structure (500) comprising a flexible substrate on which an electronics component 105 is provided. The electronics component (105) is communicatively connected to the processor 109. The flexible substrate extends through the opening (17) in the housing (101) such that the electronics component (105) is located at least partially outside of the housing (101). The processor is located within the housing.